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ENZYME

ENZYME entry: EC 2.1.1.173

Accepted Name
23S rRNA (guanine(2445)-N(2))-methyltransferase
Reaction catalysed
guanosine(2445) in 23S rRNA + S-adenosyl-L-methionine = N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine + H(+)
Comment(s)
  • The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate.
  • The enzyme specifically methylates guanine(2445) at N(2) in 23S rRNA.
  • Formerly EC 2.1.1.52.
Cross-references
BRENDA2.1.1.173
EC2PDB2.1.1.173
ExplorEnz2.1.1.173
PRIAM enzyme-specific profiles2.1.1.173
KEGG Ligand Database for Enzyme Nomenclature2.1.1.173
IUBMB Enzyme Nomenclature2.1.1.173
IntEnz2.1.1.173
MEDLINEFind literature relating to 2.1.1.173
MetaCyc2.1.1.173
Rhea expert-curated reactions2.1.1.173
UniProtKB/Swiss-Prot
Q6FCR7, RLMKL_ACIADB2HWX8, RLMKL_ACIBCB0VLH0, RLMKL_ACIBS
B0VAL5, RLMKL_ACIBYA3MYD2, RLMKL_ACTP2B3GZQ0, RLMKL_ACTP7
B0BRL8, RLMKL_ACTPJA6VMR3, RLMKL_ACTSZA0KKK7, RLMKL_AERHH
A4SME4, RLMKL_AERS4Q0VQU5, RLMKL_ALCBSQ5E5B4, RLMKL_ALIF1
B5FE19, RLMKL_ALIFMB6ELD3, RLMKL_ALISLQ0A793, RLMKL_ALKEH
Q1W3E0, RLMKL_ALLVDB4RZ48, RLMKL_ALTMDP57444, RLMKL_BUCAI
Q8K9I4, RLMKL_BUCAPB3PIL6, RLMKL_CELJUQ1QXV9, RLMKL_CHRSD
A8AID1, RLMKL_CITK8Q47Z09, RLMKL_COLP3A7MEX5, RLMKL_CROS8
Q6AQA5, RLMKL_DESPSA5EX48, RLMKL_DICNVA7ZK52, RLMKL_ECO24
Q8XDB2, RLMKL_ECO57B5YT79, RLMKL_ECO5EB1X8Q2, RLMKL_ECODH
A7ZYQ0, RLMKL_ECOHSA1A9L8, RLMKL_ECOK1Q0TJB3, RLMKL_ECOL5
Q8FJ88, RLMKL_ECOL6B1IVY4, RLMKL_ECOLCP75864, RLMKL_ECOLI
B1LJR4, RLMKL_ECOSMQ1RDR6, RLMKL_ECOUTA4W8W0, RLMKL_ENT38
B2VDF6, RLMKL_ERWT9B0U0U4, RLMKL_FRAP2Q14HS5, RLMKL_FRAT1
A7NCY2, RLMKL_FRATFQ2A2U4, RLMKL_FRATHB2SGG3, RLMKL_FRATM
A0Q621, RLMKL_FRATNQ0BLC3, RLMKL_FRATOQ5NGC3, RLMKL_FRATT
A4IXN4, RLMKL_FRATWQ7VP04, RLMKL_HAEDUQ4QP66, RLMKL_HAEI8
A5UB28, RLMKL_HAEIEA5UFS2, RLMKL_HAEIGP44524, RLMKL_HAEIN
Q2SCH1, RLMKL_HAHCHQ0I4C6, RLMKL_HISS1B0UUM5, RLMKL_HISS2
Q31IC8, RLMKL_HYDCUQ5QX63, RLMKL_IDILOB5XY56, RLMKL_KLEP3
A6T742, RLMKL_KLEP7Q5X969, RLMKL_LEGPAA5I9H3, RLMKL_LEGPC
Q5ZZI8, RLMKL_LEGPHQ5X0J6, RLMKL_LEGPLA0L8B5, RLMKL_MAGMM
Q65UK6, RLMKL_MANSMA6VW36, RLMKL_MARMSA1TZG2, RLMKL_MARN8
Q60AX5, RLMKL_METCAQ9CNW9, RLMKL_PASMUQ6D459, RLMKL_PECAS
Q7N612, RLMKL_PHOLLQ6LRA0, RLMKL_PHOPRB4EVC6, RLMKL_PROMH
Q48JX8, RLMKL_PSE14Q15UB5, RLMKL_PSEA6A6V328, RLMKL_PSEA7
Q9HZG0, RLMKL_PSEAEQ1ICL2, RLMKL_PSEE4Q4KFI6, RLMKL_PSEF5
A4XWP8, RLMKL_PSEMYA5W6K7, RLMKL_PSEP1Q3KFC5, RLMKL_PSEPF
B0KG92, RLMKL_PSEPGQ88L39, RLMKL_PSEPKB1J5B7, RLMKL_PSEPW
Q883N9, RLMKL_PSESMQ3IGZ3, RLMKL_PSET1Q4ZUM1, RLMKL_PSEU2
Q4FTN9, RLMKL_PSYA2Q1QCP8, RLMKL_PSYCKA1SX09, RLMKL_PSYIN
A5WGC0, RLMKL_PSYWFQ21JW7, RLMKL_SACD2B5F1U5, RLMKL_SALA4
A9MHU0, RLMKL_SALARQ57QU1, RLMKL_SALCHB5FQZ1, RLMKL_SALDC
B5QZF1, RLMKL_SALEPB5R6B4, RLMKL_SALG2B4TDY8, RLMKL_SALHS
B4T1Z1, RLMKL_SALNSQ5PGE3, RLMKL_SALPAA9N6Y0, RLMKL_SALPB
B5BBL9, RLMKL_SALPKB4TRX1, RLMKL_SALSVQ8Z7S6, RLMKL_SALTI
Q8ZQ73, RLMKL_SALTYA8GCK7, RLMKL_SERP5A1S601, RLMKL_SHEAM
A3D5Q0, RLMKL_SHEB5A6WPK6, RLMKL_SHEB8A9L591, RLMKL_SHEB9
Q12LC6, RLMKL_SHEDOQ07ZR3, RLMKL_SHEFNB0TIX7, RLMKL_SHEHH
A3QDY0, RLMKL_SHELPQ8EFW4, RLMKL_SHEONA8H3Y1, RLMKL_SHEPA
A4Y5X4, RLMKL_SHEPCA0KVL6, RLMKL_SHESAA8FW59, RLMKL_SHESH
Q0HJZ9, RLMKL_SHESMQ0HWA0, RLMKL_SHESRA1RKM2, RLMKL_SHESW
B1KDN0, RLMKL_SHEWMB2TUD1, RLMKL_SHIB3Q31YL1, RLMKL_SHIBS
Q32HV8, RLMKL_SHIDSQ0T686, RLMKL_SHIF8Q83RX5, RLMKL_SHIFL
Q3Z3H3, RLMKL_SHISSQ2NU80, RLMKL_SODGMB4SQ79, RLMKL_STRM5
B2FJ58, RLMKL_STRMKA4VM39, RLMKL_STUS1Q3A2U5, RLMKL_SYNC1
A7N0M8, RLMKL_VIBC1A5F836, RLMKL_VIBC3Q9KRZ5, RLMKL_VIBCH
Q87PC0, RLMKL_VIBPAQ7MKX1, RLMKL_VIBVYQ8PM40, RLMKL_XANAC
Q4UT85, RLMKL_XANC8B0RV07, RLMKL_XANCBQ8PAE0, RLMKL_XANCP
Q3BV47, RLMKL_XANE5Q2P309, RLMKL_XANOMB2SIS8, RLMKL_XANOP
Q5H029, RLMKL_XANORB2IA87, RLMKL_XYLF2Q9PA69, RLMKL_XYLFA
B0U5Z5, RLMKL_XYLFMQ87A16, RLMKL_XYLFTA1JMQ6, RLMKL_YERE8
A7FJT9, RLMKL_YERP3Q1CA41, RLMKL_YERPAB2JYS1, RLMKL_YERPB
Q7CHK7, RLMKL_YERPEA9R7L5, RLMKL_YERPGQ1CGJ3, RLMKL_YERPN
A4TMZ0, RLMKL_YERPPQ66CG1, RLMKL_YERPSB1JQR7, RLMKL_YERPY
Q9K0V4, RLML_NEIMB

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-