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ENZYME

ENZYME entry: EC 2.1.1.116

Accepted Name
3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase
Reaction catalysed
(S)-3'-hydroxy-N-methylcoclaurine + S-adenosyl-L-methionine = (S)-reticuline + S-adenosyl-L-homocysteine + H(+)
Comment(s)
  • Involved in isoquinoline alkaloid metabolism in plants.
  • Has also been shown to catalyze the methylation of (RS)- laudanosoline, (S)-3'-hydroxycoclaurine and (RS)-7- O-methylnoraudanosoline.
Cross-references
BRENDA2.1.1.116
EC2PDB2.1.1.116
ExplorEnz2.1.1.116
PRIAM enzyme-specific profiles2.1.1.116
KEGG Ligand Database for Enzyme Nomenclature2.1.1.116
IUBMB Enzyme Nomenclature2.1.1.116
IntEnz2.1.1.116
MEDLINEFind literature relating to 2.1.1.116
MetaCyc2.1.1.116
Rhea expert-curated reactions2.1.1.116
UniProtKB/Swiss-Prot
Q7XB11, 4OMT1_PAPSOQ7XB10, 4OMT2_PAPSOQ9LEL5, 4OMT_COPJA

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