ID 4.2.3.141 DE sclareol synthase. CA 8-hydroxycopalyl diphosphate + H2O = sclareol + diphosphate. CC -!- Isolated from the plant Salvia sclarea (clary sage). CC -!- Originally thought to be synthesized in one step from geranylgeranyl CC diphosphate it is now known to require two enzymes, EC 4.2.1.133 and CC EC 4.2.3.141. CC -!- Sclareol is used in perfumery. CC -!- Formerly EC 3.1.7.4. DR G8GJ94, SCLS_SALSC ; //