54 results found
    1. Neuroscience

    Connectomic analysis of the Drosophila lateral neuron clock cells reveals the synaptic basis of functional pacemaker classes

    Orie T Shafer, Gabrielle J Gutierrez ... Maria de la Paz Fernandez
    The most influential clocks within the Drosophila circadian clock neuron network form the fewest synapses within the network, and neurons that do not themselves contain molecular clocks mediate connections between those that do, suggesting a key role in timekeeping.
    1. Neuroscience

    Accelerating with FlyBrainLab the discovery of the functional logic of the Drosophila brain in the connectomic and synaptomic era

    Aurel A Lazar, Tingkai Liu ... Yiyin Zhou
    FlyBrainLab is an open-source computing platform that integrates 3D exploration and visualization of diverse Drosophila connectomic/synaptomic datasets with interactive exploration of the functional logic of modeled executable brain circuits.
    1. Neuroscience

    Information flow, cell types and stereotypy in a full olfactory connectome

    Philipp Schlegel, Alexander Shakeel Bates ... Gregory S X E Jefferis
    Synaptic resolution analysis of a full olfactory connectome reveals lateralised circuits, convergence of innate and learned pathways, and shows that homologous neurons are highly stereotyped within and across brains.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Hippocampal neural stem cells facilitate access from circulation via apical cytoplasmic processes

    Tamar Licht, Esther Sasson ... Eli Keshet
    Neural stem cells in the dentate gyrus have unique cytoplasmic processes that promote privileged access to circulating factors by a unique contact point with an endothelial cell.
    1. Computational and Systems Biology
    2. Neuroscience

    A connectome and analysis of the adult Drosophila central brain

    Louis K Scheffer, C Shan Xu ... Stephen M Plaza
    New reconstruction methods are used to create a publicly available dense reconstruction of the neurons and chemical synapses of central brain of Drosophila, with analysis of its graph properties.
    1. Neuroscience

    A visual pathway for skylight polarization processing in Drosophila

    Ben J Hardcastle, Jaison J Omoto ... Mark A Frye
    Circuit tracing and in vivo calcium imaging reveals neurons conveying polarized light information from photoreceptors to the central brain, transforming patterns in the sky into a directional cue for navigation.
    1. Computational and Systems Biology
    2. Neuroscience

    Olfactory responses of Drosophila are encoded in the organization of projection neurons

    Kiri Choi, Won Kyu Kim, Changbong Hyeon
    The organization of olfactory projection neurons and their synaptic connectivity with third-order neurons studied along with olfactory responses suggest that the labeled-line design is partially at work in the Drosophila olfactory system.
    1. Neuroscience

    The neural basis for a persistent internal state in Drosophila females

    David Deutsch, Diego Pacheco ... Mala Murthy
    A set of sexually dimorphic neurons in female flies is part of a recurrent neural network and drives minutes-long persistent neural activity and persistent social behaviors.
    1. Neuroscience

    A searchable image resource of Drosophila GAL4 driver expression patterns with single neuron resolution

    Geoffrey W Meissner, Aljoscha Nern ... FlyLight Project Team
    Single neuron images of Drosophila driver lines reveal neuron shape and are searchable, enabling comparisons to electron microscopy and prediction of intersectional neuron targeting strategies.
    1. Neuroscience

    A connectome of the Drosophila central complex reveals network motifs suitable for flexible navigation and context-dependent action selection

    Brad K Hulse, Hannah Haberkern ... Vivek Jayaraman
    An analysis of the first complete synaptic resolution connectome of Drosophila's navigation circuit uncovers neural network motifs supporting broadly relevant sensorimotor computations.

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