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- research-articleJuly 2024
Interactive Evolutionary Multiobjective Optimization of Primer Design with Uncertain Objectives
GECCO '24: Proceedings of the Genetic and Evolutionary Computation ConferencePages 1291–1299https://doi.org/10.1145/3638529.3654167The choice of primer designs for polymerase chain reaction experiments affects the results. Designing optimal combinations of forward and reverse primers requires solving multiple conflicting objectives simultaneously. Most of the tools for primer design ...
- articleDecember 2015
Fluorescence detection test by black printed circuit board based microfluidic channel for polymerase chain reaction
Technology and Health Care (TAHC), Volume 24, Issue s1Pages S139–S146https://doi.org/10.3233/THC-151061This paper proposes the optimal structure of a PCB-based micro PCR chip constructed on a PCB substrate using commercial adhesive tapes and plastic covers. The solder mask of the PCB substrate was coated black, and the area where the reaction chamber is ...
- ArticleJanuary 2014
Correctness Checking of Bio-chemical Protocol Realizations on a Digital Microfluidic Biochip
VLSID '14: Proceedings of the 2014 27th International Conference on VLSI Design and 2014 13th International Conference on Embedded SystemsPages 504–509https://doi.org/10.1109/VLSID.2014.94Recent advances in digital micro fluidic (DMF) technologies offer a promising platform for a wide variety of bio-chemical applications, such as DNA analysis, automated drug discovery, and toxicity monitoring. For on-chip implementation of complex ...
- ArticleNovember 2012
Estimation of the Influence for Different Population Sizes in MA-Based Natural SNP-RFLP Primer Design
TAAI '12: Proceedings of the 2012 Conference on Technologies and Applications of Artificial IntelligencePages 68–73https://doi.org/10.1109/TAAI.2012.59Single nucleotide polymorphisms (SNPs) are the most common genetic variations that can be genotyped effectively by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Although PCR-RFLP has become the popular technique, search ...
- ArticleMay 2012
Using Loop-mediated Isothermal DNA Amplification (LAMP) and Spectral Surface Plasmon Resonance (SPR) to Detect Methicillin-resistance S. aureus (MRSA)
ICBEB '12: Proceedings of the 2012 International Conference on Biomedical Engineering and BiotechnologyPages 647–650https://doi.org/10.1109/iCBEB.2012.462Loop-mediated isothermal amplification (LAMP) is a rapid (within an hour) and sensitive method to amplify DNA at one temperature. It has a high potential to be used as a biosensor to detect pathogens as LAMP does not require thermal cycles to amplify ...
- research-articleNovember 2006
Behavioral modeling and performance evaluation of microelectrofluidics-based PCR systems using SystemC
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems (TCADICS), Volume 23, Issue 6Pages 843–858https://doi.org/10.1109/TCAD.2004.828115Composite microsystems that incorporate microelectromechanical and microelectrofluidic devices are emerging as the next generation of system-on-a-chip (SOC). We present a performance comparison between two types of microelectrofluidic systems (MEFS): ...
- articleJanuary 2001