Export Citations
Save this search
Please login to be able to save your searches and receive alerts for new content matching your search criteria.
- research-articleJanuary 2020
Ortholog detection: pathway to comparative genomics
International Journal of Computational Intelligence in Bioinformatics and Systems Biology (IJCIBSB), Volume 2, Issue 1Pages 31–47https://doi.org/10.1504/ijcibsb.2020.106860Accurate detection of orthologs is a key aspect of comparative genomics. Orthologs can be used to predict the function of newly sequenced genes from the model organisms as they retain the same biological function through the path of evolution. In this ...
- tutorialSeptember 2013
Bacterial pan-genomes: data representation and analysis
BCB'13: Proceedings of the International Conference on Bioinformatics, Computational Biology and Biomedical InformaticsPage 683https://doi.org/10.1145/2506583.2506684Bacterial genomes at NCBI represent a large collection of strains with different levels of sequence and assembly quality as well as sampling density. Among these, there are densely-sampled sets of related genomes, usually human pathogens, whose ...
- research-articleFebruary 2010
Comparative sequence and structural analyses of neuroserpin: the serine protease inhibitor family
ISB '10: Proceedings of the International Symposium on BiocomputingArticle No.: 5, Pages 1–7https://doi.org/10.1145/1722024.1722031Neuroserpin, a clade of serine proteinase inhibitors (serpins) is a selective inhibitor of tissue-type plasminogen activator (tPA) and usually has more than 220 residues. The crystal structure of native human neuroserpin has been reported by Sayaka et ...
- research-articleJuly 2003
Applying Automatically Derived Gene-Groups to Automatically Predict and Refine Metabolic Pathways
IEEE Transactions on Knowledge and Data Engineering (IEEECS_TKDE), Volume 15, Issue 4Pages 883–894https://doi.org/10.1109/TKDE.2003.1209006This paper describes an automated technique to predict integrated pathways and refine existing metabolic pathways using the information of automatically derived, functionally similar gene-groups and orthologs (functionally equivalent genes) derived by ...
- ArticleMarch 2001
Integrating Co-regulated Gene-groups and Pair-wise Genome Comparisons to Automate Reconstruction of Microbial Pathways
BIBE '01: Proceedings of the 2nd IEEE International Symposium on Bioinformatics and BioengineeringPage 209This paper extends previously described automated techniques by automatically integrating the information about automatically derived co-transcribed gene-groups, functionally similar gene-groups derived using automated pair-wise genome comparisons and ...