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- research-articleDecember 2024
Multi-modal clear cell renal cell carcinoma grading with the segment anything model
AbstractClear cell renal cell carcinoma (ccRCC) is a prevalent kidney disease, accounting for more than 75% of renal cell carcinoma (RCC) and approximately 3.8% of human malignancies. Early grading of ccRCC is crucial in guiding personalized treatment ...
- research-articleJanuary 2025
Lung nodule classification using radiomics model trained on degraded SDCT images
Computer Methods and Programs in Biomedicine (CBIO), Volume 257, Issue Chttps://doi.org/10.1016/j.cmpb.2024.108474Highlights- Leveraging degraded SDCTs for screened lung nodule classification.
- Application of radiomics on lung nodules for developing a more explainable model.
- Potential of shape and size features to enhance lung nodule classification ...
Low-dose computed tomography (LDCT) screening has shown promise in reducing lung cancer mortality; however, it suffers from high false positive rates and a scarcity of available annotated datasets. To overcome these ...
- research-articleJanuary 2025
A time-dependent explainable radiomic analysis from the multi-omic cohort of CPTAC-Pancreatic Ductal Adenocarcinoma
- Gian Maria Zaccaria,
- Francesco Berloco,
- Domenico Buongiorno,
- Antonio Brunetti,
- Nicola Altini,
- Vitoantonio Bevilacqua
Computer Methods and Programs in Biomedicine (CBIO), Volume 257, Issue Chttps://doi.org/10.1016/j.cmpb.2024.108408Highlights- PDA prognosis with AI is a challenging task.
- Combining radiomic, clinical and mutational data can improve risk stratification.
- Time-dependent XAI is underutilized in multi-omics approaches.
- Investigation on how radiomics can ...
In Pancreatic Ductal Adenocarcinoma (PDA), multi-omic models are emerging to answer unmet clinical needs to derive novel quantitative prognostic factors. We realized a pipeline that relies on survival machine-learning (...
- research-articleJanuary 2025
Automated grading of diabetic retinopathy and Radiomics analysis on ultra-wide optical coherence tomography angiography scans
AbstractDiabetic retinopathy (DR), a progressive condition due to diabetes that can lead to blindness, is typically characterized by a number of stages, including non-proliferative (mild, moderate and severe) and proliferative DR. These stages are marked ...
Highlights- Proposed an automated method for accurate grading of DR severity on UW-OCTA images.
- Performs quality assessment, vascular abnormality segmentation and DR grading.
- Our method achieved recall values of 0.88 for vascular abnormality ...
- research-articleJanuary 2025
radMLBench: A dataset collection for benchmarking in radiomics
Computers in Biology and Medicine (CBIM), Volume 182, Issue Chttps://doi.org/10.1016/j.compbiomed.2024.109140Abstract BackgroundNew machine learning methods and techniques are frequently introduced in radiomics, but they are often tested on a single dataset, which makes it challenging to assess their true benefit. Currently, there is a lack of a larger, ...
Highlights- New methods are introduced in radiomics, but often not properly benchmarked.
- We collected 50 radiomics dataset in tabular form and with binary outcome.
- We illustrate its use by showing that decorrelating features has no large ...
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- research-articleJanuary 2025
Antibiotic profile classification of Proteus mirabilis using machine learning: An investigation into multidimensional radiomics features
Computers in Biology and Medicine (CBIM), Volume 182, Issue Chttps://doi.org/10.1016/j.compbiomed.2024.109131AbstractAntimicrobial resistance (AMR) presents a significant threat to global healthcare. Proteus mirabilis causes catheter-associated urinary tract infections (CAUTIs) and exhibits increased antibiotic resistance. Traditional diagnostics still rely on ...
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Highlights- There is a need for a new approach to tackle the rising issue of antimicrobial resistance.
- Wavelet-based Radiomics analysis of light microscopy images can identify antibiotic-resistant of P. mirabilis strains.
- The Random Forest ...
- ArticleOctober 2024
Bilinear Fine-grained Classification of Ultrasound Images Integrated with Interpretable Radiomics
AbstractUltrasound is a widely used diagnostic modality that generates substantial amounts of ultrasonic medical data. With the rapid development of deep learning and effective utilization of medical data, computer-aided intelligent diagnosis methods have ...
- ArticleOctober 2024
Assessment of Radiomics Feature Repeatability and Reproducibility and Their Generalizability Across Image Modalities by Perturbation in Nasopharyngeal Carcinoma Patients
- Zongrui Ma,
- Jiang Zhang,
- Xinzhi Teng,
- Saikit Lam,
- Yuanpeng Zhang,
- Yu-Hua Huang,
- Tian Li,
- Francis Lee,
- Jing Cai
Computational Mathematics Modeling in Cancer AnalysisPages 110–119https://doi.org/10.1007/978-3-031-73360-4_12AbstractThis study aims to evaluate the repeatability and reproducibility of radiomics features (RFs) under image perturbations and examine their generalizability across computed tomography (CT) and magnetic resonance (MR) images among nasopharyngeal ...
- ArticleSeptember 2024
MSD-HAM-Net: A Multi-modality Fusion Network of PET/CT Images for the Prognosis of DLBCL Patients
Artificial Neural Networks and Machine Learning – ICANN 2024Pages 314–327https://doi.org/10.1007/978-3-031-72353-7_23Abstract18F-FDG PET/CT images have been proven promising for the prognosis of Diffuse Large B-cell Lymphoma (DLBCL) patients. However, the implicit drawbacks of images constrain their wide applications. In this paper, we propose a fusion solution which ...
- ArticleSeptember 2024
Impact of Acquisition Parameters on the Performance of Radiomic Systems
AbstractRadiomics has emerged as a promising tool for early diagnosis of cancer using Computerised Tomography (CT) scans. However, a main concern is the reproducibility of results, particularly in cases unseen by the network. Although overfitting can ...
- research-articleNovember 2024
Altruistic seagull optimization algorithm enables selection of radiomic features for predicting benign and malignant pulmonary nodules
Computers in Biology and Medicine (CBIM), Volume 180, Issue Chttps://doi.org/10.1016/j.compbiomed.2024.108996AbstractAccurately differentiating indeterminate pulmonary nodules remains a significant challenge in clinical practice. This challenge becomes increasingly formidable when dealing with the vast radiomic features obtained from low-dose computed ...
Highlights- Altruistic mechanism is integrated into the Seagull Optimization Algorithm.
- The proposed multi-objective function accommodates to class-imbalanced datasets.
- A radiomic feature panel is selected to predict the malignant risk of lung ...
- review-articleOctober 2024
Advancements in AI based healthcare techniques with FOCUS ON diagnostic techniques
Computers in Biology and Medicine (CBIM), Volume 179, Issue Chttps://doi.org/10.1016/j.compbiomed.2024.108917AbstractSince the past decade, the interest towards more precise and efficient healthcare techniques with special emphasis on diagnostic techniques has increased. Artificial Intelligence has proved to be instrumental in development of various such ...
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Highlights- AI based techniques cane used in for various diagnostic procedures like prediction of disease, decision for medication and prognosis of a disease.
- One of the major requirements of development of AI in healthcare is large quantity of ...
- review-articleOctober 2024
Challenges and limitations in applying radiomics to PET imaging: Possible opportunities and avenues for research
Computers in Biology and Medicine (CBIM), Volume 179, Issue Chttps://doi.org/10.1016/j.compbiomed.2024.108827AbstractRadiomics, the high-throughput extraction of quantitative imaging features from medical images, holds immense potential for advancing precision medicine in oncology and beyond. While radiomics applied to positron emission tomography (PET) imaging ...
Highlights- PET Radiomics offers unique insights into tumor biology and treatment responses.
- Despite its potential, PET radiomics faces several challenges and limitations that need to be addressed to facilitate its clinical translation.
- This ...
- research-articleSeptember 2024
Multi-omics deep learning for radiation pneumonitis prediction in lung cancer patients underwent volumetric modulated arc therapy
- Wanyu Su,
- Dezhi Cheng,
- Weihua Ni,
- Yao Ai,
- Xianwen Yu,
- Ninghang Tan,
- Jianping Wu,
- Wen Fu,
- Chenyu Li,
- Congying Xie,
- Meixiao Shen,
- Xiance Jin
Computer Methods and Programs in Biomedicine (CBIO), Volume 254, Issue Chttps://doi.org/10.1016/j.cmpb.2024.108295Highlights- Predicting radiation pneumonitis in lung cancer patients undergoing radiotherapy helps improve the management of lung cancer patients.
- Combining dosiomics, radiomics, and deep learning enhances the prediction of radiation pneumonitis ...
To evaluate the feasibility and accuracy of radiomics, dosiomics, and deep learning (DL) in predicting Radiation Pneumonitis (RP) in lung cancer patients underwent volumetric modulated arc therapy (VMAT) to improve ...
- research-articleDecember 2024
Prediction model for epidermal growth factor receptor mutation status in lung cancer brain metastases with deep learning methods based on dual-modality MRI
ICBIT '24: Proceedings of the 2024 International Conference on Biomedicine and Intelligent TechnologyPages 213–218https://doi.org/10.1145/3700486.3700520Objectives: The preoperative diagnose of epidermal growth factor receptor (EGFR) is crucial for targeted therapy in non-small cell lung cancer (NSCLC) patients with brain metastases. This study aimed to assess the feasibility of using deep learning ...
- review-articleAugust 2024
Adding Dimensionality Reduction analysis of Texture descriptors for Tourette’s Syndrome classification
- Murilo Costa de Barros,
- Kauê Tartarotti Nepomuceno Duarte,
- Wang-Tso Lee,
- Chia-Jui Hsu,
- Marco Antonio Garcia de Carvalho
AbstractTourette Syndrome(TS) is a hereditary condition characterized by involuntary motor and vocal actions. Although there is no cure for TS, various prescription medications are typically provided to patients to help alleviate symptoms. Incorporating ...
- research-articleSeptember 2024
Comprehensive benchmarking of CNN-based tumor segmentation methods using multimodal MRI data
Computers in Biology and Medicine (CBIM), Volume 178, Issue Chttps://doi.org/10.1016/j.compbiomed.2024.108799AbstractMagnetic resonance imaging (MRI) has become an essential and a frontline technique in the detection of brain tumor. However, segmenting tumors manually from scans is laborious and time-consuming. This has led to an increasing trend towards fully ...
Highlights- Precision in brain tumor segmentation is pivotal for accurate diagnosis and treatment planning.
- Benchmarking the performance of four widely used CNN methods i.e., CaPTk, 2DVNet, EnsembleUNets, and ResNet50 on BraTS2021 dataset and ...
- research-articleJuly 2024
Breast cancer classification through multivariate radiomic time series analysis in DCE-MRI sequences
Expert Systems with Applications: An International Journal (EXWA), Volume 249, Issue PAhttps://doi.org/10.1016/j.eswa.2024.123557AbstractBreast cancer is the most prevalent disease that poses a significant threat to women’s health. Despite the Dynamic Contrast-Enhanced MRI (DCE-MRI) has been widely used for breast cancer classification, its diagnostic performance is still ...
Highlights- Modeling of breast cancer classification in DCE-MRI through time series algorithms.
- Radiomics enables the extraction of intelligible features also in small-dataset.
- The intelligibility of radiomic features enables accurate and ...
- research-articleJuly 2024
AATCT-IDS: A benchmark Abdominal Adipose Tissue CT Image Dataset for image denoising, semantic segmentation, and radiomics evaluation
- Zhiyu Ma,
- Chen Li,
- Tianming Du,
- Le Zhang,
- Dechao Tang,
- Deguo Ma,
- Shanchuan Huang,
- Yan Liu,
- Yihao Sun,
- Zhihao Chen,
- Jin Yuan,
- Qianqing Nie,
- Marcin Grzegorzek,
- Hongzan Sun
Computers in Biology and Medicine (CBIM), Volume 177, Issue Chttps://doi.org/10.1016/j.compbiomed.2024.108628Abstract Background and objective:The metabolic syndrome induced by obesity is closely associated with cardiovascular disease, and the prevalence is increasing globally, year by year. Obesity is a risk marker for detecting this disease. However, current ...
Highlights
- Build abdominal adipose tissue dataset containing 13,732 CT images of 300 subjects.
- Validate the dataset applied value in denoising, segmentation and radiomics research.
- This dataset is published as open source for noncommercial ...
- research-articleJuly 2024
Machine learning-based radiomics for predicting outcomes in cervical cancer patients undergoing concurrent chemoradiotherapy
Computers in Biology and Medicine (CBIM), Volume 177, Issue Chttps://doi.org/10.1016/j.compbiomed.2024.108593Abstract PurposesTo investigate the value of machine learning-based radiomics for predicting disease-free survival (DFS) and overall survival (OS) undergoing concurrent chemoradiotherapy (CCRT) for patients with locally advanced cervical cancer (LACC).
...Highlights- A multicentre large sample study has built a stable and reliable predictive tool that can efficiently predict the progression and prognosis of cervical cancer patients after concurrent chemoradiotherapy.
- Complementary of radiomics ...