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Accurate identification of patients who achieve pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) is critical before surgery for guiding customized treatment regimens and assessing prognosis in breast cancer. However, ...

• Dual-center clinical data of the myocardial ischemia and other haemodynamic indicators of 186 patients was collected in this study. The amount of data is sufficient.
• A simplified coronary stenosis-microcirculation resistance single-...

Instantaneous wave-free ratio (iFR) is a new invasive indicator of myocardial ischaemia, and its diagnostic performance is as good as the “gold standard” of myocardial ischaemia diagnosis: fractional flow reserve (FFR). ...

Dynamic Searchable Symmetric Encryption (DSSE), which enables users to search and update encrypted data on an untrusted server without decryption, is a proven method when dealing with availability issues for outsourced data. However, the existing ...

This paper revisits the anonymity of post-quantum public key encryption in the presence of CCA attacks (ANO-CCA). Specifically, we demonstrate the anonymity of key encapsulation mechanisms (KEMs) obtained from Fujisaki-Okamoto (FO) transformations ...

The reduced-order lumped parameter model (LPM) has great computational efficiency in real-time numerical simulations of haemodynamics but is limited by the accuracy of patient-specific computation. This study proposed a method to achieve the ...

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• Clinical data of 323 individuals was collected from two medical centres.
• DPNN was developed to individualize the lumped parameter model in real-time.
• The effectiveness of DPNN were verified by clinical data.
• Inefficient ...

The underuse of invasive fractional flow reserve (FFR) in clinical practice has motivated research towards non-invasive prediction of FFR. Although the non-invasive derivation of FFR (FFR_CT) using computational fluid dynamics (CFD) principles has ...

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• Developed a cascade data-drive and physical-based neural networks estimation of FFR.
• The cascade networks include coronary geometric features and physical information.
• The diagnostic accuracy of DL-FFRCT was not inferior to FFRCT.

Recently, computational fluid dynamics enables the non-invasive calculation of fractional flow reserve (FFR) based on 3D coronary model, but it is time-consuming. Currently, machine learning technique has emerged as an ...

• Reduced-order (0D) coronary model is used to replace the conventional 3D CFD model for simulating coronary flow.
• Reduced-order (0D) coronary model improves the computational efficiency.
• Machine learning model is embedded into the ...

• This study proposes a brain tissue microcirculation lumped-parameter model based on computed tomography angiography to accurately calculate the change to microcirculatory perfusion within brain tissue in real time, which can quickly and ...

Clinical diagnosis of ischemic stroke commonly relies on examining cerebral perfusion changes by using computed tomography perfusion (CTP) techniques. However, the radiation dose in CTP is quite higher in comparison to ...

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• This study proposes a 3D/0D geometric multiscale model that is based on CTA of cerebral arteries and can accurately calculate cerebral arterial flow and hemodynamic indexes.
• Based on the multiscale model, we investigated the ...

In clinical practice a large number of patients with ischemic stroke have internal carotid artery (ICA) stenosis accompanied by Circle of Willis (CoW) stenosis. In the presence of carotid artery stenosis, CoW ...

We propose a novel, efficient and secure Key Encapsulation Mechanism (KEM) transformation in the random oracle model. Furthermore, we demonstrate its security in the Quantum Random Oracle Model (QROM) as introduced by Boneh et al. (CRYPTO 12), ...

• The presented approach provides an accurate and time-efficient tool for computational fractional flow reserve.
• Hyperemia aortic pressure as the inlet boundary condition improves the accuracy of the model.
• The stenosis resistance ...

The functional assessment of the severity of coronary stenosis from coronary computed tomography angiography (CCTA)-derived fractional flow reserve (FFR) has recently attracted interest. However, existing algorithms run ...

With the rapid advancement of information and communication technology, the distinctive technical advantages of eSIM in IoT communications have become increasingly evident, capturing significant attention within the industry. However, power grid ...

Topology optimization problems with natural frequency or structural stability criteria often utilize objective or constraint functions computed from the eigenvalues of a generalized eigenvalue problem. However, design formulations involving the ...

• We determined the optimal EECP frequency for the treatment of coronary heart disease and cerebral ischemic stroke.

Currently, enhanced external counterpulsation (EECP) devices mainly produce one counterpulsation per cardiac cycle. However, the effect of other frequencies of EECP on the hemodynamics of coronary ...

• The HFMM model was established to calculate adenosine-independent indicator CT-iFR.
• CT-iFR shows great advantages in the identification of a serial lesion.
• CT-iFR represents an advancement of existing CT-FFR technology.

Coronary computed tomography angiography (CCTA) derived fractional flow reserve (CT-FFR) requires a maximal hyperemic state to be modeled by assuming the total coronary resistance decreased to a constant 0.24 of that ...

The generic $\mathsf{IND}$-$\mathsf{CCA}$ secure key encapsulation mechanism (KEM) constructions in the quantum random oracle model (QROM) attract much attention due to the NIST post-quantum competition. Most of the NIST KEM submissions follow the generic Fujisaki-...$\mathsf{}$$\mathsf{}$$\mathsf{}$$\mathsf{}$

In this paper, we answer the open question pointed out by Grubbs et al. (EUROCRYPT 2022) and Xagawa (EUROCRYPT 2022), i.e., the - security proof of . In order to add robustness, uses a slightly tweaked Fujisaki-Okamoto (FO) transformation. ...

Microservices architecture has an essential characteristic of loose coupling compared to traditional monolithic applications, allowing applications to be created, updated, and extended independently. With lightweight virtualization technologies, ...

• Aneurysmal haemodynamics of 19 patients were quantified by CFD simulations incorporating physiologically real boundary conditions measured in vivo.
• Statistically significant difference was found between simulations using generic and ...

Initiation, growth, and rupture of intracranial aneurysms are believed to be closely related to their local haemodynamic environment. While haemodynamics can be characterised by use of computational fluid dynamics (CFD), ...

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Building object detectors can identify unknown objects, which is critical yet underexplored. An additional discriminative inference pass is generally needed to generate final classification results for “unknown” class on the existing methods of ...