Background: In July 2015, Iran Food and Drug Administration convened a multi-stakeholder workgroup (workgroup) to help develop recommendations for electronic prescribing implementation in Iran.

Objectives: In general, the consensus of the workgroup was to focus on solutions that incrementally reduce the burden on patients, providers, and payers, and require minimal rework by using national standards that have already been used for Health Information Interchange. We used a road mapping method which includes a number of systematic steps and is adapted from the standard scientific method. Medical Informatics Experts Developed protocols for Scoping Reviews, Systematic reviews and Health Technology Assessment study and then collected evidence from peer-reviewed scholarly journal publications and gray literature. Health Insurance companies representatives and Electronic Prescribing pilot studies executives were asked to report their experiences in the case of e-prescribing.

Results: After five meetings, by comparing and contrasting the national and international evidence, the recommendations were finalized in expert panels. In this paper, we report recommendations from this roadmap.