Facile synthesis of water-dispersible Cu2O nanocrystal–reduced graphene oxide hybrid as a promising cancer therapeutic agent

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Facile synthesis of water-dispersible Cu₂O nanocrystal–reduced graphene oxide hybrid as a promising cancer therapeutic agent†

Chengyi Hou,^ab Haocheng Quan,^ab Yourong Duan,^c Qinghong Zhang,^a Hongzhi Wang*^a and Yaogang Li*^b

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* Corresponding authors

^a State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, People's Republic of China
E-mail: wanghz@dhu.edu.cn
Fax: +86 21-67792855
Tel: +86 21-67792881

^b Engineering Research Center of Advanced Glasses Manufacturing Technology, College of Materials Science and Engineering, Donghua University, Shanghai 201620, People's Republic of China
E-mail: yaogang_li@dhu.edu.cn
Fax: +86 21-67792855
Tel: +86 21-67792676

^c Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China

Abstract

We report a Cu₂O nanocrystal–reduced graphene oxide hybrid that is dispersible in water and has anticancer activity under both visible and near-infrared light irradiation. In contrast to the highly efficient killing of both normal and cancer cells initiated by the photothermal effect, the photocatalytic effect of this material results in the selective killing of cancer cells under visible light irradiation. These results have implications for safe and widely applicable cancer therapy agents.

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Article information

DOI: https://doi.org/10.1039/C2NR32938G
Article type: Paper
Submitted: 27 Sep 2012
Accepted: 04 Dec 2012
First published: 07 Dec 2012

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Nanoscale, 2013,5, 1227-1232

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Facile synthesis of water-dispersible Cu₂O nanocrystal–reduced graphene oxide hybrid as a promising cancer therapeutic agent

C. Hou, H. Quan, Y. Duan, Q. Zhang, H. Wang and Y. Li, Nanoscale, 2013, 5, 1227 DOI: 10.1039/C2NR32938G

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