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George M. Spyrou
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Books and Theses
- 2001
- [b1]George M. Spyrou:
Development of a simulation algorithm for mammographic imaging based on Monte Carlo methods. University of Patras, Greece, 2001
Journal Articles
- 2024
- [j36]Nestoras Karathanasis, Panayiota L. Papasavva, Anastasis Oulas, George M. Spyrou:
Combining clinical and molecular data for personalized treatment in acute myeloid leukemia: A machine learning approach. Comput. Methods Programs Biomed. 257: 108432 (2024) - [j35]Anastasis Oulas, Kyriaki Savva, Nestoras Karathanasis, George M. Spyrou:
Ranking of cell clusters in a single-cell RNA-sequencing analysis framework using prior knowledge. PLoS Comput. Biol. 20(4): 1011550 (2024) - 2023
- [j34]George Minadakis, Marios Tomazou, Nikolas Dietis, George M. Spyrou:
Vir2Drug: a drug repurposing framework based on protein similarities between pathogens. Briefings Bioinform. 24(1) (2023) - 2021
- [j33]Anna Onisiforou, George M. Spyrou:
Identification of viral-mediated pathogenic mechanisms in neurodegenerative diseases using network-based approaches. Briefings Bioinform. 22(6) (2021) - [j32]Marios Tomazou, Marilena M. Bourdakou, George Minadakis, Margarita Zachariou, Anastasis Oulas, Evangelos Karatzas, Eleni M. Loizidou, Andrea C. Kakouri, Christiana C. Christodoulou, Kyriaki Savva, Maria Zanti, Anna Onisiforou, Sotiroula Afxenti, Jan Richter, Christina G. Christodoulou, Theodoros C. Kyprianou, George Kolios, Nikolas Dietis, George M. Spyrou:
Multi-omics data integration and network-based analysis drives a multiplex drug repurposing approach to a shortlist of candidate drugs against COVID-19. Briefings Bioinform. 22(6) (2021) - [j31]Maria Zanti, Kyriaki Michailidou, Maria Loizidou, Christina Machattou, Panagiota Pirpa, Kyproula Christodoulou, George M. Spyrou, Kyriacos Kyriacou, Andreas Hadjisavvas:
Performance evaluation of pipelines for mapping, variant calling and interval padding, for the analysis of NGS germline panels. BMC Bioinform. 22(1): 218 (2021) - 2020
- [j30]Evangelos Karatzas, Juan Eiros Zamora, Emmanouil Athanasiadis, Dimitris Dellis, Zoe Cournia, George M. Spyrou:
ChemBioServer 2.0: an advanced web server for filtering, clustering and networking of chemical compounds facilitating both drug discovery and repurposing. Bioinform. 36(8): 2602-2604 (2020) - [j29]Evangelos Karatzas, Margarita Zachariou, Marilena M. Bourdakou, George Minadakis, Anastasis Oulas, George Kolios, Alex Delis, George M. Spyrou:
PathWalks: identifying pathway communities using a disease-related map of integrated information. Bioinform. 36(13): 4070-4079 (2020) - 2019
- [j28]Anastasis Oulas, George Minadakis, Margarita Zachariou, Kleitos Sokratous, Marilena M. Bourdakou, George M. Spyrou:
Systems Bioinformatics: increasing precision of computational diagnostics and therapeutics through network-based approaches. Briefings Bioinform. 20(3): 806-824 (2019) - [j27]Nikolas Dovrolis, George Kolios, George M. Spyrou, Ioanna Maroulakou:
Computational profiling of the gut-brain axis: microflora dysbiosis insights to neurological disorders. Briefings Bioinform. 20(3): 825-841 (2019) - [j26]George Minadakis, Margarita Zachariou, Anastasis Oulas, George M. Spyrou:
PathwayConnector: finding complementary pathways to enhance functional analysis. Bioinform. 35(5): 889-891 (2019) - [j25]Emmanouil K. Ikonomakis, George M. Spyrou, Michael N. Vrahatis:
Content driven clustering algorithm combining density and distance functions. Pattern Recognit. 87: 190-202 (2019) - [j24]Andrea C. Kakouri, Christiana C. Christodoulou, Margarita Zachariou, Anastasis Oulas, George Minadakis, Christiana A. Demetriou, Christina Votsi, Eleni Zamba-Papanicolaou, Kyproula Christodoulou, George M. Spyrou:
Revealing Clusters of Connected Pathways Through Multisource Data Integration in Huntington's Disease and Spastic Ataxia. IEEE J. Biomed. Health Informatics 23(1): 26-37 (2019) - 2017
- [j23]Marilena M. Bourdakou, George M. Spyrou:
Informed walks: whispering hints to gene hunters inside networks' jungle. BMC Syst. Biol. 11(1): 97:1-97:11 (2017) - [j22]Nicholas E. Protonotarios, George M. Spyrou, George A. Kastis:
Automatic cumulative sums contour detection of FBP-reconstructed multi-object nuclear medicine images. Comput. Biol. Medicine 85: 43-52 (2017) - [j21]Emmanouil Athanasiadis, Marilena M. Bourdakou, George M. Spyrou:
D-Map: Random Walking on Gene Network Inference Maps Towards differential Avenue Discovery. IEEE ACM Trans. Comput. Biol. Bioinform. 14(2): 484-490 (2017) - 2016
- [j20]John C. Siavelis, Marilena M. Bourdakou, Emmanouil I. Athanasiadis, George M. Spyrou, Konstantina S. Nikita:
Bioinformatics methods in drug repurposing for Alzheimer's disease. Briefings Bioinform. 17(2): 322-335 (2016) - [j19]George M. Tzanoukos, Erast Athanasiadis, Anastasios Gaitanis, Alexandros Georgakopoulos, Achilleas Chatziioannou, Sofia Chatziioannou, George M. Spyrou:
SPNsim: A database of simulated solitary pulmonary nodule PET/CT images facilitating computer aided diagnosis. J. Biomed. Informatics 63: 357-365 (2016) - 2015
- [j18]Stergiani V. Eleftheriou, Marilena M. Bourdakou, Emmanouil I. Athanasiadis, George M. Spyrou:
GeneStoryTeller: a mobile app for quick and comprehensive information retrieval of human genes. Database J. Biol. Databases Curation 2015 (2015) - [j17]Argiris Sakellariou, George M. Spyrou:
mAPKL: R/ Bioconductor package for detecting gene exemplars and revealing their characteristics. BMC Bioinform. 16: 291:1-291:9 (2015) - [j16]Emmanouil I. Athanasiadis, Marilena M. Bourdakou, George M. Spyrou:
ZoomOut: Analyzing Multiple Networks as Single Nodes. IEEE ACM Trans. Comput. Biol. Bioinform. 12(5): 1213-1216 (2015) - [j15]Ioannis Andreadis, George M. Spyrou, Konstantina S. Nikita:
A CAD$_{\bf x}$ Scheme for Mammography Empowered With Topological Information From Clustered Microcalcifications' Atlases. IEEE J. Biomed. Health Informatics 19(1): 166-173 (2015) - 2014
- [j14]Emmanouil Athanasiadis, Kyriaki Antonopoulou, Foteini Chatzinasiou, Christina M. Lill, Marilena M. Bourdakou, Argiris Sakellariou, Katerina Kypreou, Irene Stefanaki, Evangelos Evangelou, John P. A. Ioannidis, Lars Bertram, Alexander J. Stratigos, George M. Spyrou:
A Web-based database of genetic association studies in cutaneous melanoma enhanced with network-driven data exploration tools. Database J. Biol. Databases Curation 2014 (2014) - 2013
- [j13]Maria D. Paraskevopoulou, Ioannis S. Vlachos, Emmanouil Athanasiadis, George M. Spyrou:
BiDaS: a web-based Monte Carlo BioData Simulator based on sequence/feature characteristics. Nucleic Acids Res. 41(Webserver-Issue): 582-586 (2013) - 2012
- [j12]Emmanouil Athanasiadis, Zoe Cournia, George M. Spyrou:
ChemBioServer: a web-based pipeline for filtering, clustering and visualization of chemical compounds used in drug discovery. Bioinform. 28(22): 3002-3003 (2012) - [j11]Argiris Sakellariou, Despina Sanoudou, George M. Spyrou:
Combining multiple hypothesis testing and affinity propagation clustering leads to accurate, robust and sample size independent classification on gene expression data. BMC Bioinform. 13: 270 (2012) - 2011
- [j10]Anastasia Alexandridou, Nikolas Dovrolis, George T. Tsangaris, Konstantina S. Nikita, George M. Spyrou:
PepServe: a web server for peptide analysis, clustering and visualization. Nucleic Acids Res. 39(Web-Server-Issue): 381-384 (2011) - [j9]Argiris Sakellariou, Despina Sanoudou, George M. Spyrou:
Investigating the Minimum Required Number of Genes for the Classification of Neuromuscular Disease Microarray Data. IEEE Trans. Inf. Technol. Biomed. 15(3): 349-355 (2011) - 2010
- [j8]Georgia Giannakopoulou, George M. Spyrou, Argyro Antaraki, Ioannis Andreadis, Dimitra Koulocheri, Flora Zagouri, Afroditi Nonni, George M. Filippakis, Konstantina S. Nikita, Panos A. Ligomenides, George C. Zografos:
Downgrading BIRADS 3 to BIRADS 2 category using a computer-aided microcalcification analysis and risk assessment system for early breast cancer. Comput. Biol. Medicine 40(11-12): 853-859 (2010) - [j7]Anastasios Gaitanis, George Kontaxakis, George M. Spyrou, George Panayiotakis, George Tzanakos:
PET image reconstruction: A stopping rule for the MLEM algorithm based on properties of the updating coefficients. Comput. Medical Imaging Graph. 34(2): 131-141 (2010) - [j6]Anastasios Gaitanis, George Kontaxakis, George M. Spyrou, George Panayiotakis, George Tzanakos:
Studying the properties of the updating coefficients in the OSEM algorithm for iterative image reconstruction in PET. Comput. Methods Programs Biomed. 99(3): 219-229 (2010) - [j5]Ioannis K. Valavanis, George M. Spyrou, Konstantina S. Nikita:
A similarity network approach for the analysis and comparison of protein sequence/structure sets. J. Biomed. Informatics 43(2): 257-267 (2010) - 2009
- [j4]Anastasia Alexandridou, George T. Tsangaris, Konstantinos N. Vougas, Konstantina S. Nikita, George M. Spyrou:
UniMaP: finding unique mass and peptide signatures in the human proteome. Bioinform. 25(22): 3035-3037 (2009) - 2008
- [j3]Anastasia Alexandridou, George T. Tsangaris, Konstantinos N. Vougas, Konstantina S. Nikita, George M. Spyrou:
Peptide Finder: mapping measured molecular masses to peptides and proteins. Bioinform. 24(19): 2267-2269 (2008) - 2007
- [j2]Trias Thireou, George M. Spyrou, Vassilis Atlamazoglou:
A Survey of the Availability of Primary Bioinformatics Web Resources. Genom. Proteom. Bioinform. 5(1): 70-76 (2007) - 2006
- [j1]George M. Spyrou, Smaragda Kapsimalakou, Antonis Frigas, Konstantinos Koufopoulos, Stamatios Vassilaros, Panos A. Ligomenides:
"Hippocrates-mst": a prototype for computer-aided microcalcification analysis and risk assessment for breast cancer. Medical Biol. Eng. Comput. 44(11): 1007-1015 (2006)
Conference and Workshop Papers
- 2021
- [c19]Emmanouil K. Ikonomakis, Marilena M. Bourdakou, George Kolios, Michael N. Vrahatis, George M. Spyrou:
Computational insights on the molecular mechanisms across breast cancer progression combining gene differential expression and co-expression. BHI 2021: 1-5 - 2019
- [c18]Andrea C. Kakouri, Christina Votsi, Marios Tomazou, Kyproula Christodoulou, George M. Spyrou:
The Effect of a Spastic Ataxia Associated GBA2 Mutation on Protein-Protein Interactions and Pathways. BIBE 2019: 18-22 - [c17]Evangelos Karatzas, Alex Delis, George Kolios, George M. Spyrou:
Exploring Fibrotic Disease Networks to Identify Common Molecular Mechanisms with IPF. BIBE 2019: 72-77 - [c16]Maria Zanti, Maria Loizidou, Margarita Zachariou, Kyriaki Michailidou, Kyriacos C. Kyriacou, Andreas Hadjisavvas, George M. Spyrou:
In Silico Assessment of the Structural, Functional and Stability Impact of a Nonsense PRF1 Mutation with Uncertain Clinical Significance; Identified in 2 Unrelated Cypriot Triple-Negative Breast Cancer Patients. BIBE 2019: 182-187 - [c15]Christiana C. Christodoulou, George Minadakis, Christiana Demetriou, Eleni Zamba-Papanicolaou, George M. Spyrou:
Computational Identification of Metabolites for Pathways Related to Huntington's Disease. BIBE 2019: 832-837 - [c14]George M. Tzanoukos, Pavlos Kafouris, Alexandros Georgakopoulos, Anastasios Gaitanis, Dimitris Maroulis, Sofia Chatziioannou, George M. Spyrou:
Design and Initial Implementation of a Computer Aided Diagnosis System for PET/CT Solitary Pulmonary Nodule Risk Estimation. BIBE 2019: 1024-1028 - 2013
- [c13]Ioannis Andreadis, George M. Spyrou, Panos A. Ligomenides, Konstantina S. Nikita:
Generation of clustered microcalcifications' atlases for benign and malignant cases. BIBE 2013: 1-4 - [c12]Ioannis Andreadis, George M. Spyrou, Panos A. Ligomenides, Konstantina S. Nikita:
Variations on breast density and subtlety of the findings require different computational intelligence pipelines for the diagnosis of clustered microcalcifications. BIBE 2013: 1-4 - [c11]Emmanouil K. Ikonomakis, George M. Spyrou, Panos A. Ligomenides, Michael N. Vrahatis:
Performance evaluation of clustering algorithms on microcalcifications as mammography findings. BIBE 2013: 1-4 - [c10]Efthymios Maneas, Stratis Tzoumas, Vasilis Ntziachristos, George M. Spyrou:
Developing a simulator for multispectral optoacoustic tomography. BIBE 2013: 1-4 - [c9]George M. Tzanoukos, Anastasios Gaitanis, Alexandros Georgakopoulos, Achilleas Chatziioannou, Sofia Chatziioannou, George M. Spyrou:
Modeling of solitary pulmonary nodules in PET/CT images using Monte Carlo methods. BIBE 2013: 1-4 - 2012
- [c8]Paraskevi Gkeka, Emmanouil Athanasiadis, George M. Spyrou, Zoe Cournia:
Enhancing the effectiveness of virtual screening by using the ChemBioServer: Application to the discovery of PI3Kα inhibitors. BIBE 2012: 266-269 - [c7]Katerina N. Karayianni, George M. Spyrou, Konstantina S. Nikita:
Clustering microarray data using fuzzy clustering with viewpoints. BIBE 2012: 362-367 - [c6]Alexandros C. Dimopoulos, John Lakoumentas, Argyro Antaraki, Antonis Frigas, Emmanouil K. Ikonomakis, Marinos Sampson, Anastasios Tagaris, Aikaterini Liakou, Emmanouil Athanasiadis, George M. Spyrou, Panos A. Ligomenides:
e-Prolipsis: A web based risk estimation platform to support and register breast cancer diagnosis in Greece. BIBE 2012: 434-438 - 2009
- [c5]Antonis Frigas, George M. Spyrou, Argyro Antaraki, Elisabeth Patiraki, Konstantinos Koufopoulos, John Mantas, Panos A. Ligomenides:
Design of a 'Smart' Patient Record System for Mammography Patients. MIE 2009: 130-134 - 2008
- [c4]Vassilis Atlamazoglou, Trias Thireou, Anastasia Alexandridou, George M. Spyrou:
A high throughput approach to keep alive a web-based database system for multiple search among published bioinformatics tools and databases. BIBE 2008: 1-4 - [c3]Ioannis K. Valavanis, George M. Spyrou, Konstantina S. Nikita:
Protein similarity networks and Genetic Algorithm driven feature selection for fold recognition. BIBE 2008: 1-6 - 2006
- [c2]Xenofon E. Floros, George M. Spyrou, Konstantinos N. Vougas, George T. Tsangaris, Konstantina S. Nikita:
Study on Preprocessing and Classifying Mass Spectral Raw Data Concerning Human Normal and Disease Cases. ISBMDA 2006: 390-401 - [c1]Antonis Frigas, Smaragda Kapsimalakou, George M. Spyrou, Konstantinos Koufopoulos, Stamatios Vassilaros, Aikaterini Chatzimichael, John Mantas, Panos A. Ligomenides:
Evaluation of a Breast Cancer Computer Aided Diagnosis System. MIE 2006: 631-636
Coauthor Index
aka: Emmanouil I. Athanasiadis
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