EP 3265103 A4 20181114 - COMPOSITIONS AND METHODS FOR TREATING OCULAR DISEASES
Title (en)
COMPOSITIONS AND METHODS FOR TREATING OCULAR DISEASES
Title (de)
ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BEHANDLUNG VON AUGENERKRANKUNGEN
Title (fr)
COMPOSITIONS ET MÉTHODES DE TRAITEMENT DE MALADIES OCULAIRES
Publication
Application
Priority
- US 201562127362 P 20150303
- US 2016020683 W 20160303
Abstract (en)
[origin: WO2016141182A1] The compositions and methods disclosed herein provide for treatments of ocular disorders of the eye, such as ocular surface diseases as well as those associated with inflammation of internal cells and cell layers of the eye. The methods disclosed herein describe methods for treating ocular disorders, particularly dry eye disorders, comprising topically administering to an ocular region of a subject a composition comprising a pharmaceutically effective amount of at least one aldosterone antagonist or salt thereof and a pharmaceutically acceptable carrier. Included is a method for treating dry eye comprising topically administering to an ocular region of a subject a composition comprising spironolactone and hydroxypropyl methylcellulose; and reducing or preventing one or more symptoms or causes of dry eye.
IPC 8 full level
A61K 31/585 (2006.01); A61K 31/136 (2006.01); A61K 45/06 (2006.01); A61P 27/02 (2006.01)
CPC (source: EP US)
A61K 9/0048 (2013.01 - EP US); A61K 31/136 (2013.01 - EP US); A61K 31/145 (2013.01 - EP US); A61K 31/585 (2013.01 - EP US); A61K 45/06 (2013.01 - EP US); A61K 47/10 (2013.01 - US); A61K 47/38 (2013.01 - US); A61P 27/02 (2018.01 - EP)
C-Set (source: EP US)
Citation (search report)
- [XDY] US 3551554 A 19701229 - HERSCHLER ROBERT JOHN
- [XY] WO 03049745 A1 20030619 - PHARMACIA CORP [US], et al
- [X] WO 2014202744 A1 20141224 - INSERM INST NAT DE LA SANTÉ ET DE LA RECH MÉDICALE [FR], et al
- [Y] KAWAI S: "Cornea protective agent for use in ophthalmic composition for suppressing advance of corneal trauma e.g. dry eyes or corneal ulcer, contains hydroxypropyl methylcellulose", WPI / 2017 CLARIVATE ANALYTICS,, vol. 2006, no. 76, 19 October 2006 (2006-10-19), XP002764851
- [Y] TAUBER J: "Efficacy, tolerability and comfort of a 0.3% hypromellose gel ophthalmic lubricant in the treatment of patients with moderate to severe dry eye syndrome", CURRENT MEDICAL RESEARCH AND OPINION, INFORMA HEALTHCARE, GB, vol. 23, no. 11, 31 October 2007 (2007-10-31), pages 2629 - 2636, XP009508344, ISSN: 0300-7995, [retrieved on 20070913], DOI: 10.1185/030079907X233197
- [Y] TODA I ET AL: "Hydroxypropyl methylcellulose for the treatment of severe dry eye associated with Sjogren's syndrome", vol. 15, no. 2, 1 March 1996 (1996-03-01), pages 120 - 128, XP009508345, ISSN: 0277-3740, Retrieved from the Internet <URL:https://journals.lww.com/corneajrnl/Abstract/1996/03000/Hydroxypropyl_Methylcellulose_for_the_Treatment_of.3.aspx> [retrieved on 20180927]
- See also references of WO 2016141182A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2016141182 A1 20160909; EP 3265103 A1 20180110; EP 3265103 A4 20181114; EP 3265103 B1 20240724; EP 3265103 C0 20240724; ES 2984281 T3 20241029; JP 2018510855 A 20180419; JP 6861634 B2 20210421; US 10350223 B2 20190716; US 2018050049 A1 20180222
DOCDB simple family (application)
US 2016020683 W 20160303; EP 16759492 A 20160303; ES 16759492 T 20160303; JP 2017545950 A 20160303; US 201615555527 A 20160303