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Global Patent Index - EP 1144448 A3

EP 1144448 A3 20020306 - TIAM2 (T-CELL LYMPHOMA INVASION AND METASTASIS 2) NUCLEOTIDE EXCHANGE FACTOR

Title (en)

TIAM2 (T-CELL LYMPHOMA INVASION AND METASTASIS 2) NUCLEOTIDE EXCHANGE FACTOR

Title (de)

TIAM2 (T-ZELL-LYMPHOM INVASION UND METASTASE 2 ) NUKLEOTIDEAUSTAUSCHFAKTOR

Title (fr)

ADN CODANT LES PROTEINES TIAM-2 ET PROCEDE D'UTILISATION DUDIT ADN

Publication

EP 1144448 A3 20020306 (EN)

Application

EP 00902369 A 20000106

Priority

  • US 0000459 W 20000106
  • US 22727899 A 19990106

Abstract (en)

[origin: WO0040607A2] The present invention provides nucleic acid sequences encoding TIAM2 proteins. The invention also includes diagnostic assays, expression vectors, antisense molecules, ribozymes, and host cells to express the polypeptide encoded by the nucleic acid sequence. The present invention also includes claims to the polypeptide sequence encoded by the nucleic acid sequences.

IPC 1-7

C07K 14/415; C12N 15/63; C07K 16/18; C12N 15/11; G01N 33/53

IPC 8 full level

G01N 33/53 (2006.01); A61K 39/395 (2006.01); C07K 14/47 (2006.01); C07K 14/82 (2006.01); C07K 16/32 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12P 21/02 (2006.01); C12Q 1/68 (2006.01); G01N 33/566 (2006.01)

CPC (source: EP)

A61P 35/00 (2017.12); C07K 14/4702 (2013.01)

Citation (search report)

  • [X] WO 9746680 A1 19971211 - CHIRON CORP [US], et al
  • [PX] CHIU C.Y. ET AL.: "Cloning and characterization of T-cell lymphoma invasion and metastasis 2 (TIAM2), a novel guanine nucleotide exchange factor related to TIAM1.", GENOMICS, vol. 61, no. 1, 1 October 1999 (1999-10-01), pages 66-73, XP000864676 & CHIU C.Y. ET AL.: "Erratum: Cloning and characterization of T-cell lymphoma invasion and metastasis 2 (TIAM2), a novel guanine nucleotide exchange factor related to TIAM1.", GENOMICS, vol. 63, no. 3, 2000, pages 439, XP000864677
  • [PX] HOSHINO M. ET AL.: "Identification of the stef Gene That Encodes a Novel Guanine Nucleotide Exchange Factor Specific for Rac1", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 274, no. 25, 18 June 1999 (1999-06-18), pages 17837 - 17844, XP002141545 & HOSHINO M.: "Mus musculus Stef mRNA for sif and Tiam1-like exchange factor, complete cds", EMBL DATABASE ENTRY AB022915; ACCESSION NO. AB022915, 30 June 1999 (1999-06-30), XP002141546
  • [DA] LEEUWEN F.N. ET AL.: "The Guanine Nucleotide Exchange Factor Tiam1 Affects Neuronal Morphology; Opposing Roles for the Small GTPases Rac and Rho", JOURNAL OF CELL BIOLOGY, vol. 139, no. 3, 3 November 1997 (1997-11-03), pages 797 - 807, XP002141547
  • See references of WO 0040607A2

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0040607 A2 20000713; WO 0040607 A3 20011101; AU 2409700 A 20000724; EP 1144448 A2 20011017; EP 1144448 A3 20020306; JP 2002538774 A 20021119; JP 2010233574 A 20101021; JP 2011083295 A 20110428; JP 4707235 B2 20110622

DOCDB simple family (application)

US 0000459 W 20000106; AU 2409700 A 20000106; EP 00902369 A 20000106; JP 2000592315 A 20000106; JP 2010117840 A 20100521; JP 2011020242 A 20110201