EP 1073460 A4 20010523 - NUCLEIC ACID ENCODING HYALURONAN SYNTHASE AND METHODS OF USE
Title (en)
NUCLEIC ACID ENCODING HYALURONAN SYNTHASE AND METHODS OF USE
Title (de)
NUKLEINSÄURE KODIEREND FÜR HYALURONAN SYNTHASE UND METHODEN ZUR VERWENDUNG
Title (fr)
ACIDE NUCLEIQUE CODANT UNE HYALURONAN SYNTHASE ET SES METHODES D'UTILISATION
Publication
Application
Priority
- US 9907289 W 19990401
- US 8041498 P 19980402
- US 17885198 A 19981026
Abstract (en)
[origin: WO9951265A1] The present invention relates to a nucleic acid segment having a coding region segment encoding enzymatically active bacterial multocida hyaluronate synthase (PmHAS), and to the use of this nucleic acid segment in the preparation of recombinant cells which produce hyaluronate synthase and its hyaluronic acid product. Hyaluronate is also known as hyaluronic acid or hyaluronan. The present invention also relates to the use of the PmHAS in constructing "knock-out" mutant strains of P. multocida for use in vaccinations. The present invention further relates to the use of the PmHAS in diagnostic tests in the field determinations of livestock P. multocida infection.
IPC 1-7
A61K 39/02; C12Q 1/68; C12N 1/00; C12N 1/15; C12N 5/10; C12N 9/10; C12N 15/54; C12N 15/63; C12P 19/04
IPC 8 full level
G01N 33/48 (2006.01); A61K 39/00 (2006.01); A61K 39/102 (2006.01); A61K 47/36 (2006.01); A61P 31/04 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 9/00 (2006.01); C12N 9/10 (2006.01); C12N 15/09 (2006.01); C12P 19/04 (2006.01); C12Q 1/02 (2006.01); C12Q 1/68 (2006.01); G01N 33/53 (2006.01); G01N 33/566 (2006.01)
CPC (source: EP)
A61K 39/102 (2013.01); A61P 31/04 (2017.12); C12N 9/1051 (2013.01); C12P 19/04 (2013.01); C12Q 1/689 (2013.01)
Citation (search report)
- [A] WO 9400463 A2 19940106 - MURST ITALIAN [IT], et al
- [A] WO 9103559 A1 19910321 - UNIV TEXAS [US]
- [A] WO 9720061 A1 19970605 - SCRIPPS RESEARCH INST [US], et al
- [E] WO 9923227 A2 19990514 - UNIV OKLAHOMA [US]
- [E] WO 0027437 A2 20000518 - UNIV OKLAHOMA [US]
- [A] P H WEIGEL ET AL: "Hyaluronan synthases", JOURNAL OF BIOLOGICAL CHEMISTRY,US,AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, vol. 272, no. 22, 30 May 1997 (1997-05-30), pages 13997 - 14000, XP002105370, ISSN: 0021-9258
- [T] DEANGELIS PAUL L ET AL: "Identification and molecular cloning of a chondroitin synthase from Pasteurella multocida type F.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 275, no. 31, 4 August 2000 (2000-08-04), pages 24124 - 24129, XP002163608, ISSN: 0021-9258
- See references of WO 9951265A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9951265 A1 19991014; WO 9951265 A9 20000413; AT E501275 T1 20110315; AU 3548599 A 19991025; AU 770903 B2 20040304; BR 9909346 A 20010911; CA 2326821 A1 19991014; CA 2326821 C 20100928; CN 101275143 A 20081001; CN 1304317 A 20010718; CN 1327894 C 20070725; CZ 20003576 A3 20010912; DE 69943276 D1 20110421; EP 1073460 A1 20010207; EP 1073460 A4 20010523; EP 1832662 A2 20070912; EP 1832662 A3 20071107; EP 1832662 B1 20110309; IL 138803 A0 20011031; JP 2002510648 A 20020409; JP 2008283974 A 20081127; JP 4490581 B2 20100630; JP 4887333 B2 20120229
DOCDB simple family (application)
US 9907289 W 19990401; AT 07007453 T 19990401; AU 3548599 A 19990401; BR 9909346 A 19990401; CA 2326821 A 19990401; CN 200710109863 A 19990401; CN 99806942 A 19990401; CZ 20003576 A 19990401; DE 69943276 T 19990401; EP 07007453 A 19990401; EP 99917339 A 19990401; IL 13880399 A 19990401; JP 2000542035 A 19990401; JP 2008146037 A 20080603