EP 0915969 A4 20020417 - METHOD FOR PREVENTING HIV-1 INFECTION OF CD4+ CELLS
Title (en)
METHOD FOR PREVENTING HIV-1 INFECTION OF CD4+ CELLS
Title (de)
UNTERDRÜCKUNG DER INFEKTION VON CD4+ ZELLEN DURCH HIV
Title (fr)
METHODE DE PREVENTION DE L'INFECTION DES CELLULES CD4+ PAR LE VIH-1
Publication
Application
Priority
- US 9705597 W 19970402
- US 62768496 A 19960402
- US 66361696 A 19960614
- US 67368296 A 19960625
Abstract (en)
[origin: WO9737005A1] This invention provides methods for inhibiting fusion of HIV-1 to CD4<+> cells which comprise contacting CD4<+> cells with a non-chemokine agent capable of binding to a chemokine receptor in an amount and under conditions such that fusion of HIV-1 to the CD4<+> cells is inhibited. This invention also provides methods for inhibiting HIV-1 infection of CD4<+> cells which comprise contacting CD4<+> cells with a non-chemokine agent capable of binding to a chemokine receptor in an amount and under conditions such that fusion of HIV-1 to the CD4<+> cells is inhibited, thereby inhibiting the HIV-1 infection. This invention provides non-chemokine agents capable of binding to the chemokine receptor and inhibiting fusion of HIV-1 to CD4<+> cells. This invention also provides pharmaceutical compositions comprising an amount of the non-chemokine agent capable of binding to the chemokine receptor and inhibiting fusion of HIV-1 to CD4<+> cells effective to prevent fusion of HIV-1 to CD4<+> cells and a pharmaceutically acceptable carrier.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 31/00 (2006.01); A61K 38/00 (2006.01); A61K 38/19 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 47/48 (2006.01); A61P 31/00 (2006.01); A61P 31/18 (2006.01); C07K 7/00 (2006.01); C07K 14/47 (2006.01); C07K 14/715 (2006.01); C07K 16/00 (2006.01); C07K 16/28 (2006.01); C12N 5/07 (2010.01); C12N 5/0783 (2010.01)
CPC (source: EP)
A61K 38/195 (2013.01); A61P 31/00 (2017.12); A61P 31/18 (2017.12); C07K 14/7158 (2013.01); C07K 16/2866 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
- [E] WO 9728258 A1 19970807 - NAT INST HEALTH [US]
- [E] WO 9744462 A1 19971127 - PASTEUR INSTITUT [FR], et al
- [DA] F. COCCHI ET AL.: "IDENTIFICATION OF RANTES, MIP-1ALPHA, AND MIP-1BETA AS THE MAJOR HIV-SUPPRESSIVE FACTORS PRODUCED BY CD8+ T CELLS", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 270, 15 December 1995 (1995-12-15), pages 1811 - 1815, XP000616644, ISSN: 0036-8075
- [PX] ARENZANA-SEISDEDOS F ET AL: "HIV BLOCKED BY CHEMOKINE ANTAGONIST", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 383, 3 October 1996 (1996-10-03), pages 400, XP002025860, ISSN: 0028-0836
- See references of WO 9737005A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9737005 A1 19971009; AU 2607497 A 19971022; AU 728512 B2 20010111; CA 2250829 A1 19971009; EP 0915969 A1 19990519; EP 0915969 A4 20020417; JP 2000507596 A 20000620; JP 2008069148 A 20080327
DOCDB simple family (application)
US 9705597 W 19970402; AU 2607497 A 19970402; CA 2250829 A 19970402; EP 97917856 A 19970402; JP 2007220275 A 20070827; JP 53561097 A 19970402