MAPITR: MArginal ePIstasis Test for Regions
A genetic analysis tool and variance component
model for identifying marginal epistasis between pathways
and the rest of the genome. 'MAPITR' uses as input a matrix
of genotypes, a vector of phenotypes, and a list of
pathways. 'MAPITR' then iteratively tests each pathway for
epistasis between any variants within the pathway versus
any variants remaining in the rest of the genome. 'MAPITR'
returns results in the form of p-values for every pathway
indicating whether the null model of there being no
epistatic interactions between a pathway and the rest of
the genome can be rejected.
| Version: |
1.1.2 |
| Depends: |
R (≥ 3.3.0) |
| Imports: |
stats, doParallel, Rcpp (≥ 1.0.5), CompQuadForm |
| LinkingTo: |
Rcpp, RcppArmadillo |
| Suggests: |
testthat, knitr, rmarkdown |
| Published: |
2020-09-28 |
| DOI: |
10.32614/CRAN.package.MAPITR |
| Author: |
Michael Turchin 
[aut, cre],
Gregory Darnell
[aut, ctb],
Lorin Crawford
[aut, ctb],
Sohini Ramachandran
[aut],
Peter Carbonetto
[ctb] |
| Maintainer: |
Michael Turchin <michael_turchin at brown.edu> |
| BugReports: |
https://github.com/mturchin20/MAPITR/issues |
| License: |
MIT + file LICENSE |
| URL: |
https://github.com/mturchin20/MAPITR |
| NeedsCompilation: |
yes |
| Materials: |
README |
| CRAN checks: |
MAPITR results |
Documentation:
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