Major of three pyruvate decarboxylase isozymes; key enzyme in alcoholic fermentation; decarboxylates pyruvate to acetaldehyde; involved in amino acid catabolism; subject to glucose-, ethanol-, and autoregulation; activated by phosphorylation in response to glucose levels; N-terminally propionylated in vivo [Source:SGD;Acc:S000004034]
Chromosome XII: 232,390-234,081 reverse strand.
R64-1-1:BK006945.2
This gene has 1 transcript (splice variant), 198 orthologues and 4 paralogues.