Reaction: 3 malonyl-CoA + 3-hydroxybenzoyl-CoA = 4 CoA + 2,3',4,6-tetrahydroxybenzophenone + 3 CO2
For diagram of reaction click here.
Other name(s): benzophenone synthase (ambiguous); BPS (ambiguous)
Systematic name: malonyl-CoA:3-hydroxybenzoyl-CoA malonyltransferase (decarboxylating, 2,3',4,6-tetrahydroxybenzophenone-forming)
Comments: Involved in the biosynthesis of plant xanthones. Benzoyl-CoA can replace 3-hydroxybenzoyl-CoA (cf. EC 2.3.1.220, 2,4,6-trihydroxybenzophenone synthase).
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 175780-21-9
References:
1. Beerhues, L. Benzophenone synthase from cultured cells of Centaurium erythraea. FEBS Lett. 383 (1996) 264-266. [PMID: 8925910]