General
Preferred name
RADEZOLID
Synonyms
RX-1741 ()
RX-01_667 ()
RX-013 ()
RX-O1_667 ()
RX-103 ()
RX-1741_667 ()
RX-1741667 ()
Radezolid hcl ()
AND RX-01_667 ()
RX-01 ()
RADEZOLID HYDROCHLORIDE ()
P&D ID
PD012727
CAS
869884-78-6
869884-77-5
Tags
available
drug candidate
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Radezolid (RX-1741) is an oxazolidinone class antibacterial. It has activity against Gram-positive and Gram-negative bacteria.
(GtoPdb)
DESCRIPTION
Radezolid is a novel oxazolidinone antibiotic being developed by Rib-X Pharmaceuticals, Inc. for the treatment of serious multi-drug-resistant infections. It has completed two phase-II clinical trials.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
8
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
Guide to Pharmacology
MedChem Express Bioactive Compound Library
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
31
Molecular Weight
438.18
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
3
Rotatable Bonds
8
Ring Count
4
Aromatic Ring Count
3
cLogP
2.36
TPSA
112.24
Fraction CSP3
0.27
Chiral centers
1.0
Largest ring
6.0
QED
0.5
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
MOA
bacterial 30S ribosomal subunit inhibitor, bacterial 50S ribosomal subunit inhibitor
Pathway
Anti-infection
Target
antibiotic
Bacterial
Source data