General
Preferred name
RAPASTINEL
Synonyms
Thr-Pro-Pro-Thr-NH2 ()
GLYX-13 Trifluoroacetate ()
Thr-Pro-Pro-Thr-NH2 Trifluoroacetate ()
Rapastinel Trifluoroacetate ()
GLYX-13 ()
GLYX-13 (Trifluoroacetate) ()
GLYX 13 ()
Rapastinel (Trifluoroacetate) ()
Rapastinel (GLYX-13) ()
BV-102, TPPT-amide ()
TPPT-amide ()
Rapastinelum ()
GLYX 13 ()
P&D ID
PD070040
CAS
1435786-04-1
117928-94-6
Tags
available
drug candidate
Drug indication
Major depressive disorder
Drug Status
investigational
Max Phase
3.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
10
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugMAP
MedChem Express Bioactive Compound Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
24
Properties
(calculated by RDKit )
Molecular Weight
413.23
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
5
Rotatable Bonds
7
Ring Count
2
Aromatic Ring Count
0
cLogP
-2.97
TPSA
179.29
Fraction CSP3
0.78
Chiral centers
6.0
Largest ring
5.0
QED
0.3
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
iGluR
NMDA Receptor
NMDAR
Pathway
Membrane Transporter/Ion Channel
Neuroscience
Neuronal Signaling
MOA
glutamate receptor agonist
Source data