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Mycophenolic acid for psoriasis

Arch Dermatol. 1977 Sep;113(9):1203-8.

Abstract

Mycophenolic acid is an antimetabolite used experimentally for the treatment of psoriasis. Thirty-eight patients were treated with mycophenolic acid. A double-blind, placebo-controlled study demonstrated the efficacy of mycophenolic acid (P less than .01). A long-term safety study showed the occurrence of hematologic abnormalities, viral infections, and carcinoma. The position of mycophenolic acid in the therapeutic treatment of psoriasis must await the results of a multicenter cooperative study.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Breast Neoplasms / chemically induced
  • Carcinoma, Squamous Cell / chemically induced
  • Clinical Trials as Topic
  • Double-Blind Method
  • Epiglottis
  • Female
  • Humans
  • Laryngeal Neoplasms / chemically induced
  • Male
  • Middle Aged
  • Mycophenolic Acid / adverse effects
  • Mycophenolic Acid / pharmacology
  • Mycophenolic Acid / therapeutic use*
  • Psoriasis / drug therapy*
  • Virus Diseases / etiology

Substances

  • Mycophenolic Acid