Super-resolved fluorescence microscopy: Nobel Prize in Chemistry 2014 for Eric Betzig, Stefan Hell, and William E. Moerner

Angew Chem Int Ed Engl. 2014 Dec 15;53(51):13972-7. doi: 10.1002/anie.201410265. Epub 2014 Nov 4.

Authors

Leonhard Möckl¹, Don C Lamb, Christoph Bräuchle

Affiliation

¹ Department for Chemistry and Center for NanoScience (CeNS), University of Munich (LMU), Butenandtstrasse 5-13 (E), 81377 Munich (Germany).

PMID: 25371081
DOI: 10.1002/anie.201410265

Abstract

A big honor for small objects: The Nobel Prize in Chemistry 2014 was jointly awarded to Eric Betzig, Stefan Hell, and William E. Moerner "for the development of super-resolved fluorescence microscopy". This Highlight describes how the field of super-resolution microscopy developed from the first detection of a single molecule in 1989 to the sophisticated techniques of today.

Keywords: Nobel Prize; PALM; STED; single molecule detection; super-resolution.