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Chronic urticaria

MedGen UID:
537829
Concept ID:
C0263338
Disease or Syndrome
Synonyms: Chronic Urticaria; Chronic Urticarias; Urticaria, Chronic
SNOMED CT: Chronic urticaria (51611005); Recurrent periodic urticaria (51611005)
 
Monarch Initiative: MONDO:0850230

Definition

An urticaria that is characterized by the presence of urticaria for a period exceeding 6 weeks, assuming symptoms for most days of the week. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChronic urticaria

Professional guidelines

PubMed

Hon KL, Leung AKC, Ng WGG, Loo SK
Recent Pat Inflamm Allergy Drug Discov 2019;13(1):27-37. doi: 10.2174/1872213X13666190328164931. PMID: 30924425Free PMC Article
Schaefer P
Am Fam Physician 2017 Jun 1;95(11):717-724. PMID: 28671445
Bernstein JA, Lang DM, Khan DA, Craig T, Dreyfus D, Hsieh F, Sheikh J, Weldon D, Zuraw B, Bernstein DI, Blessing-Moore J, Cox L, Nicklas RA, Oppenheimer J, Portnoy JM, Randolph CR, Schuller DE, Spector SL, Tilles SA, Wallace D
J Allergy Clin Immunol 2014 May;133(5):1270-7. doi: 10.1016/j.jaci.2014.02.036. PMID: 24766875

Recent clinical studies

Etiology

Muñoz M, Kiefer LA, Pereira MP, Bizjak M, Maurer M
Curr Allergy Asthma Rep 2024 Aug;24(8):457-469. Epub 2024 Jul 19 doi: 10.1007/s11882-024-01160-y. PMID: 39028396Free PMC Article
Bernstein JA, Maurer M, Saini SS
J Allergy Clin Immunol 2024 May;153(5):1229-1240. Epub 2023 Dec 21 doi: 10.1016/j.jaci.2023.12.008. PMID: 38141832
Zheng H, Xiao XJ, Shi YZ, Zhang LX, Cao W, Zheng QH, Zhong F, Hao PS, Huang Y, Chen ML, Zhang W, Zhou SY, Wang YJ, Wang C, Zhou L, Chen XQ, Yang ZQ, Zou ZH, Zhao L, Liang FR, Li Y
Ann Intern Med 2023 Dec;176(12):1617-1624. Epub 2023 Nov 14 doi: 10.7326/M23-1043. PMID: 37956431
Saini S, Shams M, Bernstein JA, Maurer M
J Allergy Clin Immunol Pract 2020 Jun;8(6):1866-1874. Epub 2020 Apr 13 doi: 10.1016/j.jaip.2020.03.030. PMID: 32298850
Bernstein JA, Lang DM, Khan DA, Craig T, Dreyfus D, Hsieh F, Sheikh J, Weldon D, Zuraw B, Bernstein DI, Blessing-Moore J, Cox L, Nicklas RA, Oppenheimer J, Portnoy JM, Randolph CR, Schuller DE, Spector SL, Tilles SA, Wallace D
J Allergy Clin Immunol 2014 May;133(5):1270-7. doi: 10.1016/j.jaci.2014.02.036. PMID: 24766875

Diagnosis

Kolkhir P, Muñoz M, Asero R, Ferrer M, Kocatürk E, Metz M, Xiang YK, Maurer M
J Allergy Clin Immunol 2022 Jun;149(6):1819-1831. doi: 10.1016/j.jaci.2022.04.010. PMID: 35667749
Pozderac I, Lugović-Mihić L, Artuković M, Stipić-Marković A, Kuna M, Ferček I
Acta Dermatovenerol Alp Pannonica Adriat 2020 Sep;29(3):141-148. PMID: 32975301
Saini S, Shams M, Bernstein JA, Maurer M
J Allergy Clin Immunol Pract 2020 Jun;8(6):1866-1874. Epub 2020 Apr 13 doi: 10.1016/j.jaip.2020.03.030. PMID: 32298850
Saini SS, Kaplan AP
J Allergy Clin Immunol Pract 2018 Jul-Aug;6(4):1097-1106. doi: 10.1016/j.jaip.2018.04.013. PMID: 30033911Free PMC Article
Bernstein JA, Lang DM, Khan DA, Craig T, Dreyfus D, Hsieh F, Sheikh J, Weldon D, Zuraw B, Bernstein DI, Blessing-Moore J, Cox L, Nicklas RA, Oppenheimer J, Portnoy JM, Randolph CR, Schuller DE, Spector SL, Tilles SA, Wallace D
J Allergy Clin Immunol 2014 May;133(5):1270-7. doi: 10.1016/j.jaci.2014.02.036. PMID: 24766875

Therapy

Maurer M, Casale TB, Saini SS, Ben-Shoshan M, Giménez-Arnau AM, Bernstein JA, Yagami A, Stjepanovic A, Radin A, Staudinger HW, Patel N, Amin N, Akinlade B, Fan C, Bauer D, Yancopoulos GD, Patel K, Mannent LP, Laws E
J Allergy Clin Immunol 2024 Jul;154(1):184-194. Epub 2024 Feb 29 doi: 10.1016/j.jaci.2024.01.028. PMID: 38431226
Maurer M, Berger W, Giménez-Arnau A, Hayama K, Jain V, Reich A, Haemmerle S, Lheritier K, Walsh P, Xia S, Storim J
J Allergy Clin Immunol 2022 Dec;150(6):1498-1506.e2. Epub 2022 Sep 9 doi: 10.1016/j.jaci.2022.08.027. PMID: 36096203
Shakuntulla F, Chiarella SE
J Allergy Clin Immunol Pract 2022 Dec;10(12):3149-3155. Epub 2022 Aug 18 doi: 10.1016/j.jaip.2022.08.013. PMID: 35987486Free PMC Article
Muñoz-Bellido FJ, Moreno E, Dávila I
J Investig Allergol Clin Immunol 2022 Apr 19;32(2):97-115. Epub 2021 Mar 3 doi: 10.18176/jiaci.0682. PMID: 33661102
Schaefer P
Am Fam Physician 2017 Jun 1;95(11):717-724. PMID: 28671445

Prognosis

Maurer M, Kolkhir P, Pereira MP, Siebenhaar F, Witte-Händel E, Bergmann KC, Bonnekoh H, Buttgereit T, Fluhr JW, Frischbutter S, Grekowitz EM, Herzog L, Kiefer LA, Krause K, Magerl M, Muñoz M, Neisinger S, Nojarov N, Prins S, Pyatilova P, Ramanauskaité A, Scheffel J, Terhorst-Molawi D, Treudler R, Weller K, Zuberbier T, Metz M
Allergy 2024 Sep;79(9):2396-2413. Epub 2024 Jul 24 doi: 10.1111/all.16243. PMID: 39044706
Larenas-Linnemann D
Curr Allergy Asthma Rep 2023 Dec;23(12):655-664. Epub 2023 Dec 8 doi: 10.1007/s11882-023-01117-7. PMID: 38064133
Greiner B, Nicks S, Adame M, McCracken J
Clin Rev Allergy Immunol 2022 Dec;63(3):381-389. Epub 2022 Sep 1 doi: 10.1007/s12016-022-08952-y. PMID: 36048326
Fok JS, Kolkhir P, Church MK, Maurer M
Allergy 2021 Oct;76(10):2965-2981. Epub 2021 Feb 27 doi: 10.1111/all.14757. PMID: 33539587
Hon KL, Leung AKC, Ng WGG, Loo SK
Recent Pat Inflamm Allergy Drug Discov 2019;13(1):27-37. doi: 10.2174/1872213X13666190328164931. PMID: 30924425Free PMC Article

Clinical prediction guides

Kolkhir P, Bonnekoh H, Metz M, Maurer M
JAMA 2024 Nov 5;332(17):1464-1477. doi: 10.1001/jama.2024.15568. PMID: 39325444
Jain V, Giménez-Arnau A, Hayama K, Reich A, Carr W, Tillinghast J, Dahale S, Lheritier K, Walsh P, Zharkov A, Hugot S, Haemmerle S
J Allergy Clin Immunol 2024 Feb;153(2):479-486.e4. Epub 2023 Oct 20 doi: 10.1016/j.jaci.2023.10.007. PMID: 37866460
Zheng H, Xiao XJ, Shi YZ, Zhang LX, Cao W, Zheng QH, Zhong F, Hao PS, Huang Y, Chen ML, Zhang W, Zhou SY, Wang YJ, Wang C, Zhou L, Chen XQ, Yang ZQ, Zou ZH, Zhao L, Liang FR, Li Y
Ann Intern Med 2023 Dec;176(12):1617-1624. Epub 2023 Nov 14 doi: 10.7326/M23-1043. PMID: 37956431
Maurer M, Berger W, Giménez-Arnau A, Hayama K, Jain V, Reich A, Haemmerle S, Lheritier K, Walsh P, Xia S, Storim J
J Allergy Clin Immunol 2022 Dec;150(6):1498-1506.e2. Epub 2022 Sep 9 doi: 10.1016/j.jaci.2022.08.027. PMID: 36096203
Metz M, Vadasz Z, Kocatürk E, Giménez-Arnau AM
Clin Rev Allergy Immunol 2020 Aug;59(1):38-45. doi: 10.1007/s12016-020-08794-6. PMID: 32418171Free PMC Article

Recent systematic reviews

Badloe FMS, Grosber M, Ring J, Kortekaas Krohn I, Gutermuth J
J Eur Acad Dermatol Venereol 2024 Nov;38(11):2082-2092. Epub 2024 Feb 29 doi: 10.1111/jdv.19904. PMID: 38420865
Donnelly J, Ridge K, O'Donovan R, Conlon N, Dunne PJ
BMC Psychol 2023 Aug 19;11(1):239. doi: 10.1186/s40359-023-01284-2. PMID: 37598202Free PMC Article
Iriarte Sotés P, Armisén M, Usero-Bárcena T, Rodriguez Fernández A, Otero Rivas MM, Gonzalez MT, Meijide Calderón A, Veleiro B; Urtigal, the Galician Group of Interest in Urticaria
J Investig Allergol Clin Immunol 2021 Jul 26;31(4):282-291. Epub 2020 Oct 8 doi: 10.18176/jiaci.0649. PMID: 33030434
Fricke J, Ávila G, Keller T, Weller K, Lau S, Maurer M, Zuberbier T, Keil T
Allergy 2020 Feb;75(2):423-432. Epub 2019 Oct 11 doi: 10.1111/all.14037. PMID: 31494963
Guillén-Aguinaga S, Jáuregui Presa I, Aguinaga-Ontoso E, Guillén-Grima F, Ferrer M
Br J Dermatol 2016 Dec;175(6):1153-1165. Epub 2016 Oct 19 doi: 10.1111/bjd.14768. PMID: 27237730

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