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Gouty arthropathy

MedGen UID:
406
•Concept ID:
C0003868
•
Disease or Syndrome
Synonyms: Arthritides, Gouty; Arthritis, Gouty; Gouty Arthritides; Gouty Arthritis
SNOMED CT: Joints gout affected (170733007); Gouty arthropathy (190828008); Arthritis due to gout (48440001); Articular gout (48440001); Gouty arthritis (48440001)

Definition

Arthritis, especially of the great toe, as a result of gout. Acute gouty arthritis often is precipitated by trauma, infection, surgery, etc. The initial attacks are usually monoarticular but later attacks are often polyarticular. Acute and chronic gouty arthritis are associated with accumulation of MONOSODIUM URATE in and around affected joints. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGouty arthropathy

Professional guidelines

PubMed

Gout: A Rapid Review of Presentation, Diagnosis and Management.
Badshah M, Nadeem I, Ahmed I, Naim T, Fanciullo J
S D Med 2024 Feb;77(2):81-86. PMID: 38986162
Management of gout by Moroccan rheumatologists: a Moroccan Society for Rheumatology National Survey.
Moulay Berkchi J, Rkain H, Benbrahim L, Aktaou S, Lazrak N, Faiz S, Ahid S, Abouqal R, Labzizi S, Ouzeddoun N, Oukerraj L, Hmamouchi I, Hajjaj-Hassouni N, Allali F
Rheumatol Int 2020 Sep;40(9):1399-1408. Epub 2020 May 23 doi: 10.1007/s00296-020-04599-0. PMID: 32447422
Treatment of hyperuricemia, gout and other crystalline arthritidies.
Lioté F
Reumatismo 2012 Jan 19;63(4):276-83. doi: 10.4081/reumatismo.2011.276. PMID: 22303534

Recent clinical studies

Etiology

Gout: A Rapid Review of Presentation, Diagnosis and Management.
Badshah M, Nadeem I, Ahmed I, Naim T, Fanciullo J
S D Med 2024 Feb;77(2):81-86. PMID: 38986162
Genetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization study.
Li X, Meng X, He Y, Spiliopoulou A, Timofeeva M, Wei WQ, Gifford A, Yang T, Varley T, Tzoulaki I, Joshi P, Denny JC, Mckeigue P, Campbell H, Theodoratou E
PLoS Med 2019 Oct;16(10):e1002937. Epub 2019 Oct 18 doi: 10.1371/journal.pmed.1002937. PMID: 31626644Free PMC Article
Hyperuricaemia: more than just a cause of gout?
Katsiki N, Karagiannis A, Athyros VG, Mikhailidis DP
J Cardiovasc Med (Hagerstown) 2013 Jun;14(6):397-402. doi: 10.2459/JCM.0b013e3283595adc. PMID: 23032963
Gout and hyperuricemia.
Chilappa CS, Aronow WS, Shapiro D, Sperber K, Patel U, Ash JY
Compr Ther 2010;36:3-13. PMID: 21229813
Axial gouty arthropathy.
Saketkoo LA, Robertson HJ, Dyer HR, Virk ZU, Ferreyro HR, Espinoza LR
Am J Med Sci 2009 Aug;338(2):140-6. doi: 10.1097/MAJ.0b013e3181a3dc14. PMID: 19680018

Diagnosis

Severe and Uncommon Features of Gouty Arthropathy.
Almeida DE, Costa E, Neves JS, Cerqueira M, Ribeiro AR
J Clin Rheumatol 2021 Oct 1;27(7):e253. doi: 10.1097/RHU.0000000000001385. PMID: 32332266
Genetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization study.
Li X, Meng X, He Y, Spiliopoulou A, Timofeeva M, Wei WQ, Gifford A, Yang T, Varley T, Tzoulaki I, Joshi P, Denny JC, Mckeigue P, Campbell H, Theodoratou E
PLoS Med 2019 Oct;16(10):e1002937. Epub 2019 Oct 18 doi: 10.1371/journal.pmed.1002937. PMID: 31626644Free PMC Article
Gouty arthropathy: Review of clinico-pathologic and imaging features.
Parathithasan N, Lee WK, Pianta M, Oon S, Perera W
J Med Imaging Radiat Oncol 2016 Feb;60(1):9-20. Epub 2015 Oct 5 doi: 10.1111/1754-9485.12356. PMID: 26439321
Gouty arthropathy of the axial skeleton causing cord compression and myelopathy.
Ibrahim GM, Ebinu JO, Rubin LA, de Tilly LN, Spears J
Can J Neurol Sci 2011 Nov;38(6):918-20. doi: 10.1017/s031716710001252x. PMID: 22030432
Axial gouty arthropathy.
Saketkoo LA, Robertson HJ, Dyer HR, Virk ZU, Ferreyro HR, Espinoza LR
Am J Med Sci 2009 Aug;338(2):140-6. doi: 10.1097/MAJ.0b013e3181a3dc14. PMID: 19680018

Therapy

Gout: A Rapid Review of Presentation, Diagnosis and Management.
Badshah M, Nadeem I, Ahmed I, Naim T, Fanciullo J
S D Med 2024 Feb;77(2):81-86. PMID: 38986162
Erosive Gouty Arthropathy Resulting in a Telescoping Digit.
Liew JW, Thomason JL
J Clin Rheumatol 2019 Dec;25(8):e133. doi: 10.1097/RHU.0000000000000793. PMID: 31764501
Genetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization study.
Li X, Meng X, He Y, Spiliopoulou A, Timofeeva M, Wei WQ, Gifford A, Yang T, Varley T, Tzoulaki I, Joshi P, Denny JC, Mckeigue P, Campbell H, Theodoratou E
PLoS Med 2019 Oct;16(10):e1002937. Epub 2019 Oct 18 doi: 10.1371/journal.pmed.1002937. PMID: 31626644Free PMC Article
Gout and hyperuricemia.
Chilappa CS, Aronow WS, Shapiro D, Sperber K, Patel U, Ash JY
Compr Ther 2010;36:3-13. PMID: 21229813
Acute gouty arthropathy after total knee arthroplasty.
Salin JW, Lombardi AV Jr, Berend KR, Chonko DJ
Am J Orthop (Belle Mead NJ) 2008 Aug;37(8):420-2. PMID: 18836601

Prognosis

Plasma adsorption in refractory chronic gouty arthritis flare: A case report.
Lei Y, Cui TJ, Wang XH, Zhang XM, Tang C, Zheng ZH
Front Immunol 2022;13:1045982. Epub 2022 Nov 24 doi: 10.3389/fimmu.2022.1045982. PMID: 36505444Free PMC Article
Pretreatment and Coadministration With Methotrexate Improved Durability of Pegloticase Response: An Observational, Proof-of-Concept Case Series.
Botson JK, Peterson J
J Clin Rheumatol 2022 Jan 1;28(1):e129-e134. doi: 10.1097/RHU.0000000000001639. PMID: 33044389Free PMC Article
Tophaceous gouty arthropathy of the lumbar spine.
Saripalli K, Baskar S
Clin Med (Lond) 2014 Dec;14(6):683-4. doi: 10.7861/clinmedicine.14-6-683. PMID: 25468860Free PMC Article
Hyperuricaemia: more than just a cause of gout?
Katsiki N, Karagiannis A, Athyros VG, Mikhailidis DP
J Cardiovasc Med (Hagerstown) 2013 Jun;14(6):397-402. doi: 10.2459/JCM.0b013e3283595adc. PMID: 23032963
Clinical outcome of tibiotalar arthrodesis utilizing the chevron technique.
Kopp FJ, Banks MA, Marcus RE
Foot Ankle Int 2004 Apr;25(4):225-30. doi: 10.1177/107110070402500406. PMID: 15132930

Clinical prediction guides

Pretreatment and Coadministration With Methotrexate Improved Durability of Pegloticase Response: An Observational, Proof-of-Concept Case Series.
Botson JK, Peterson J
J Clin Rheumatol 2022 Jan 1;28(1):e129-e134. doi: 10.1097/RHU.0000000000001639. PMID: 33044389Free PMC Article
Genetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization study.
Li X, Meng X, He Y, Spiliopoulou A, Timofeeva M, Wei WQ, Gifford A, Yang T, Varley T, Tzoulaki I, Joshi P, Denny JC, Mckeigue P, Campbell H, Theodoratou E
PLoS Med 2019 Oct;16(10):e1002937. Epub 2019 Oct 18 doi: 10.1371/journal.pmed.1002937. PMID: 31626644Free PMC Article
Bone erosions in patients with chronic gouty arthropathy are associated with tophi but not bone oedema or synovitis: new insights from a 3 T MRI study.
McQueen FM, Doyle A, Reeves Q, Gao A, Tsai A, Gamble GD, Curteis B, Williams M, Dalbeth N
Rheumatology (Oxford) 2014 Jan;53(1):95-103. Epub 2013 Sep 29 doi: 10.1093/rheumatology/ket329. PMID: 24080252
Consecutive stages of arthropathy progression in patients with gout.
Kawenoki-Minc E, Maldyk E, Polowiec Z
Z Rheumatol 1977 Mar-Apr;36(3-4):106-11. PMID: 860604
Effect of balneotherapy in Ciechocinek Spa on the occurrence of gouty attacks and the symptoms of chronic gouty arthropathy (observations of 112 cures).
Kawenoki-Minc E, Zieliński Z
Pol Med J 1972;11(6):1494-500. PMID: 4659072

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