Search Results (798)

Physical activity interventions and programming for Black American girls often overlook racism and sexism as a fundamental cause of the differences in engagement between their white and male peers. Deficit framing is a standard where Black girls are often compared to the health, physical activity, and beauty standards driven by white feminine or masculine norms, suggesting there is only one way to be fit and healthy. Approaches that lack cultural and historical relevance, including the effects of systemic racism and sexism, are seldom considered before aiming to increase physical activity engagement and favorable health outcomes for Black teenage girls. Aim: This paper presents a brief overview of physical activity programming for Black adolescent girls and young women (aged 14–18) and proposes theoretical frameworks and approaches to consider before implementing physical activity interventions and programs. Concluding Remarks: Voice, intersectionality, misogynoir, representation, and gendered racism as a root cause should inform physical activity programming designed for Black adolescent girls. Culturally equitable approaches for real and sustainable change are required to increase physical activity engagement. Full article

Mycotoxins, as prevalent contaminants in the food chain, exhibit diverse toxicological effects on both animals and humans. Chronic dietary exposure to mycotoxin-contaminated foods may result in the bioaccumulation of these toxins, posing substantial public health risks. This review systematically examines the contamination patterns of mycotoxins across major food categories, including cereals and related products, animal-derived foods, fruits, and medical food materials. Furthermore, we critically evaluated two methodological frameworks for assessing mycotoxin exposure risks: (1) dietary exposure models integrating contamination levels and consumption data and (2) human biomonitoring approaches quantifying mycotoxin biomarkers in biological samples. A key contribution lies in the stratified analysis of exposure disparities among population subgroups (adults, teenagers, children, and infants). Additionally, we summarize current research on the relationship between human mycotoxin biomonitoring and associated health impacts, with a particular emphasis on vulnerable groups such as pregnant women and infants. By elucidating the challenges inherent in existing studies, this synthesis provides a roadmap for advancing risk characterization and evidence-based food safety interventions. Full article

Background/Objectives: The psychological health of deaf children and adolescents with cochlear implants (CIs) appears to be related to the degree of auditory and linguistic recovery achieved, as well as contextual factors. Few studies have investigated the influence that maternal psychological characteristics and resources may have in supporting the mental health of these children and adolescents. The aim of this pilot study was to investigate the psychological well-being of pre-teens/teenagers with CIs and the mental health of their mothers. The secondary aim was to analyze which maternal characteristics (anxiety, depression, resilience, and time spent sharing emotions) were most related to the psychological health of the pre-teen/teenager. Methods: A group of 15 pre-teens/teenagers with CIs and 27 hearing peers and their mothers participated in the study. The Strengths and Difficulties Questionnaire, the Generalized Anxiety Disorder Scale, the Beck Depression Inventory II, the Connor–Davidson Resilience Scale, and an additional ad hoc question quantifying the time that the mothers dedicate to conversing with their sons/daughters about the emotions were administered to the included subjects. Results: No significant differences between the two groups of pre-teens/teenagers emerged; however, a great percentage of pre-teens/teenagers with CIs appeared at higher risk for developing psychopathology. The resilience scores for both groups of mothers were lower than anticipated and related to the psychological health of pre-teens/teenagers. Conclusions: These results underscore the need for targeted psychological support alongside auditory rehabilitation and suggest avenues for enhancing family-centered care in this clinical population. Full article

The motivation shown by teachers in the early stages of their professional development affects their future professional competence and adaptability to an occupational setting. This study explores the motivational variables that affect satisfaction with choosing a degree in pedagogy in Chile by comparing teachers in training with in-service teachers. A quantitative non-experimental and correlational–explanatory design was used, surveying 758 participants (328 teachers in training and 430 in-service teachers) using the FIT-Choice questionnaire. Results reveal that intrinsic motivations, such as the desire to work with children, teenagers, and previous teaching experiences, have a strong positive correlation with satisfaction in both groups. This reveals the importance of encouraging and strengthening practical experience in initial teacher training. Furthermore, the differences in the value of job security and social contribution reflect the evolution of motivation from initial teacher training up to professional practice. Full article

Background/Objectives: Early pediatric cochlear implantation positively impacts early language outcomes. The Teenager and Young Adults Cochlear Implant (TAYACI) study investigates the long-term outcomes of early implantation and factors influencing variability among cochlear implant (CI) users. This article outlines participants’ background, early language outcomes, and multidisciplinary study protocol. Methods and Materials: Individuals aged 12–22 received CIs before 30 months of age, followed-up at the same hearing implant center, and adhered to a standard school curriculum were invited to participate. Out of 109 eligible CI users, 50 participated; 46 agreed to undergo clinical assessments, while four completed questionnaires only. Results: The mean age at the first CI was 15.63 months (SD = 6.0). All but one communicated with spoken language(s). Participants attended mainstream schools and had highly educated parents. Over half (56%) had received Auditory Verbal Therapy in early childhood. Earlier implantation correlated with better language understanding one year post-CI. Conclusions: Earlier implantation was associated with better early language outcomes, with parental education level and early family-centered intervention likely contributing. Future sub-studies will investigate multidisciplinary long-term effects of pediatric cochlear implantation in adolescents. Full article

Background/Objectives: Bone age assessments are essential for evaluating the growth and skeletal development of children and adolescents, influenced by factors such as genetics, ethnicity, culture, and nutrition. Clinical standards for these assessments must be adapted to the specific populations under study. This study validates the use of the Tanner–Whitehouse 3 method for determining bone age in pediatric and adolescent populations in the Canary Islands. Methods: This cross-sectional study analyzed 214 posteroanterior radiographs of the left hand and wrist from 80 females and 134 males, aged between 5 and 18 years. The radiographs were independently evaluated by three raters: a Radiologist Specialist (Rater 1), a General Practitioner (Rater 2), and a Medical Student (Rater 3). Intra- and inter-rater reliability were assessed using intraclass correlation coefficients (ICCs). Accuracy was evaluated by comparing estimated bone age with chronological age, stratified by sex and developmental stage. Results: Strong intra-rater reliability was observed across all raters. Raters 1 and 2 demonstrated excellent consistency (ICCs: 0.990–0.996), while Rater 3 exhibited slightly lower yet robust reliability (ICCs: 0.921–0.976). Inter-rater agreement was high between Raters 1 and 2 but decreased with Rater 3, reflecting the influence of experience (ICCs: 0.812–0.912). Bone age was underestimated in preschool children (mean difference: 3.712 mos.; 95% CI: 1.290–6.130; p = 0.199) and school-age males (mean difference: 3.978 mos.; 95% CI: −12.550 to 4.590; p = 0.926), with minimal discrepancies in females. In teenagers, the Tanner–Whitehouse 3 method slightly overestimated bone age (mean difference: −0.360 mos.; 95% CI: −0.770 to −0.954; p = 0.299). Conclusions: In conclusion, the Tanner–Whitehouse 3 method demonstrates overall precision and reliability but requires caution, as it underestimates bone age in preschool children and school-age males, while slightly overestimating it in adolescents. Full article

In general, young people, and adolescents under protective measures, do not have the digital competence and autonomy necessary to successfully interact with public administrations. Children have the right to quality education that promotes listening, participation, equal access and opportunities, especially in the digital age. However, this remains a global challenge that cannot be waived. For this reason, the main objective of this study is to know the impact of the implementation of a Participatory Action Research (PAR) project carried out with young people living in four sheltered housing facilities in four cities in northwestern Spain. The aim of this project is to improve the digital literacy and autonomy of young people in carrying out procedures and formalities with public administrations and bodies, making them participants in their own learning process. The research was carried out using a qualitative methodology. In total, 44 subjects from different groups (30 adolescents and 14 social educators) participated. As results and conclusions, it is worth highlighting that the experience has improved the digital literacy and autonomy of the young people, observing their progress throughout the sessions. Likewise, the teenagers have actively participated in all the sessions, getting involved and learning through content of interest to them. The level of satisfaction has been very high. Full article

In recent years, youth social action has emerged as a novel concept which strives to empower young people, creating an engaged and socially aware youth population. The aim of this narrative review was to summarise, explain, and interpret international research evidence to understand the effectiveness of youth social action interventions implemented with young people between the ages of 8 and 16 years. This study followed the General Framework of Narrative Reviews. Peer-reviewed studies published in the English language that explicitly addressed ‘youth social action’ or ‘social action’ within the title or abstract were identified by means of electronic searches on EBSCOhost (Education Research Complete, MEDLINE and Child Development and Adolescent Studies databases). Search terms included “Social Action” OR “Youth Social Action” AND population (Child* OR Youth OR Adolesc* OR “School Child” OR Juvenile OR Teenag*) AND study design (intervention OR project OR evaluation OR initiative OR program*). Sixteen studies were included after full-text screening, detailing eight individual youth social action interventions. The findings revealed a range of psychosocial, health, and personal development benefits for youth who participated in social action interventions. However, the evidence base was limited by poor methodological reporting and a lack of process evaluations to confirm implementation fidelity. Future research should utilitise stronger research designs, assess both individual and community outcomes, and include follow-up measures to determine the long-term impacts of youth social action projects. Full article

Food insecurity is a growing public health concern, particularly among vulnerable groups such as adolescents, and it has been linked to poor nutritional outcomes and increased risk of chronic diseases. The Mediterranean diet (MedDiet) is recognized for its numerous health benefits, yet few studies have explored the association between food insecurity and adherence to the MedDiet among adolescents, especially in Mediterranean regions. Objective: This study aimed to investigate the association between food insecurity and adherence to the MedDiet in a sample of adolescents from Spain. Methods: Data were acquired from 2021–2022 school years from adolescents aged 12–17 years enrolled in different secondary schools in Valle de Ricote, Region of Murcia, Spain. Food security was assessed via the Spanish Child Food Security Survey Module (CFSSM-S), and adherence to the MedDiet was assessed via the Mediterranean Diet Quality Index for Children and Adolescents (KIDMED). A total of 836 participants were involved, and statistical analyses were conducted via linear regression models adjusted for lifestyle, anthropometric, and sociodemographic covariates. Results: After adjusting for potential confounders, the mean KIDMED score was 7.0 (95% confidence interval [CI] 6.7 to 7.2) in the food-security group, 6.8 (95% CI 6.3 to 7.3) in the low-security group, and 5.9 (95% CI 4.9 to 6.9) in the very-low-security group. Notable differences were observed between participants with food security and their counterparts with very low food security (p = 0.040). Compared with those with food security (57.2%, 95% CI 51.5% to 62.8%), a significantly greater likelihood of having nonoptimal adherence to the MedDiet was identified in adolescents with low food security (61.6%, 95% CI 50.4% to 71.8%) and in those with very low food security (77.4%, 95% CI 54.5% to 90.7%). We identified a significant difference only between adolescents with food security and their peers with very low food security (p = 0.036). Conclusions: The findings suggest that very low food security negatively impacts MedDiet adherence in adolescents. Compared with their food-secure peers, adolescents with very low food security showed significantly poorer diet quality. These results highlight the importance of addressing food insecurity through low-cost, high-nutrition programs aimed at improving healthy eating habits, particularly for children and adolescents living in low-food-security households. Full article

Using micro-structure components in spectacle lenses has enabled myopia progression control in children and teenagers. However, the optical design of these spectacle lenses has never been discussed, leading to a lack of correct understanding of the underlying optical treatment principles. In this work, array-patterned hexagonal lenslets with two powers of opposite signs were proposed to construct a lenslet array-integrated (LARI) spectacle lens developed for an ongoing, randomized, controlled clinical trial and to support the optical approach to myopia control leveraging retinal image blur. We found that the phase modulation induced by the micro-structures of the lenslet array contributes to the increase in RMS wavefront aberrations, leading to image blur, further inspiring the novel array-patterned micro-structure design with high-order phase elements (HOPEs). The optical performance of both LARI and HOPE spectacle lenses was investigated by simulation and experiment. Full article

Background/Objectives: The second highest prevalence of childhood malnutrition in the world is found in Nigeria. Infant and young child feeding practices (IYCF) are crucial predictors of the nutritional status of children. This study evaluated the effects of utilization of the BabyThrive app versus control on IYCF knowledge of Nigerian teenage mothers. Methods: A parallel, randomized controlled trial was conducted with 194 low-income teenage mother–child (0–2 years) dyads in Nigeria. Outcome measures included knowledge concerning food type for an infant, exclusive breastfeeding, complementary feeding, and total IYCF knowledge scores. Results: No significant differences in demographic characteristics or IYCF knowledge were found at baseline. Post-intervention, almost all BabyThrive participants vs. only 36.1% of controls were aware that expressed breast milk is the ideal food for an infant <6 months, when a mother resumes work (p < 0.05). As compared to the BabyThrive group, knowledge of how to maintain breast milk supply (5.2% vs. 83.5%), the duration of safety of breast milk at room temperature (15.4% vs. 85.6%), responsive feeding (58.8% vs. 96.9) and dietary diversity (15.5% vs. 99%) was substantially lower in controls (p < 0.05). Mean knowledge on exclusive breastfeeding (25.17 ± 1.37 vs. 19.87 ± 1.80), complementary feeding (15.68 ± 0.60, vs. 13.51 ± 1.21) and total knowledge scores (46.8 ± 1.79 vs. 38.65 ± 2.71) was higher in the BabyThrive group (p < 0.05). Conclusions: In sum, the BabyThrive app significantly increased maternal IYCF knowledge in comparison with controls. It will be a useful tool to improve maternal IYCF knowledge in resource-limited areas. Full article

SCAPs (Stem Cells from Apical Papilla), derived from the apex of forming wisdom teeth, extracted from teenagers for orthodontic reasons, belong to the MSCs (Mesenchymal Stromal Cells) family. They have multipotent differentiation capabilities and are a potentially powerful model for investigating strategies of clinical cell therapies. Since autophagy—a regulated self-eating process—was proposed to be essential in osteogenesis, we investigated its involvement in the SCAP model. By using a combination of chemical and genetic approaches to inhibit autophagy, we studied early and late events of osteoblastic differentiation. We showed that blocking the formation of autophagosomes with verteporfin did not induce a dramatic alteration in early osteoblastic differentiation monitored by ALP (alkaline phosphatase) activity. However, blocking the autophagy flux with bafilomycin A1 led to ALP repression. Strikingly, the mineralization process was observed with both compounds, with calcium phosphate (CaP) nodules that remained inside cells under bafilomycin A1 treatment and numerous but smaller CaP nodules after verteporfin treatment. In contrast, deletion of Atg5 or Atg7, two genes involved in the formation of autophagosomes and essential to trigger canonical autophagy, indicated that both genes could be involved differently in the mineralization process with a modification of the ALP activity while final mineralization was not altered. Full article

In recent years, self-injury attempts have accounted for 46.2% of emergency room visits by teenagers and young adults. This study aimed to explore the prevalence of non-suicidal self-injury (NSSI) among Korean college students, compare the mean number of NSSI risk factors between those with a history of NSSI and a control group with no history of thoughts or experiences of self-injury, and identify which factors have a greater influence on NSSI. The participants consisted of 403 Korean college students aged 18–29 who were divided into a subject group with a history of NSSI (n = 198) and a comparison group (n = 205) with no history of NSSI. The Functional Assessment of Self-Mutilation (FASM), Childhood Trauma Questionnaire (CTQ-SF), Social Experience Questionnaire (SEQ), Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder 7-item scale (GAD-7), Difficulties in Emotion Regulation Scale—16 item version (DERS-16), Experiences in Close Relationship Questionnaire-Revised (ECR-R), Rosenberg Self-Esteem Scale (RSES), Parents as Social Context Questionnaire-Kids (PSCQ-KA), and Barratt Impulsiveness Scale-11-Revised (BIS-11). The collected data were analyzed using SPSS 25.0. Before a regression analysis, a MANOVA was performed to examine the mean difference between groups of each dependent variable, and a multiple regression analysis was performed to confirm the influence. The mean difference in all risk factors in the subject group compared with the comparison group was found to be statistically significant, with an effect size of 0.8 or greater. As a result of examining the relative influence of each variable on NSSI, emotional dysregulation (t = 2.481, p = 0.014), anxiety (t = −2.109, p = 0.036), and adult attachment (t = 2.004, p = 0.046) were found to significantly influence NSSI (p = 0.05). These findings will serve as fundamental data for screening clients at risk of self-injury in counseling and treatment settings, in addition to providing preventive and therapeutic interventions. Full article

Background/Objectives: Children and teenagers display a distinct metabolic dysfunction-associated steatohepatitis (MASH) phenotype, yet studies of childhood MASH are scarce and validated animal models lacking, limiting the development of treatments. Poor vitamin C (VitC) status may affect MASH progression and often co-occurs with high-fat diets and related metabolic imbalances. As a regulator of DNA methylation, poor VitC status may further contribute to MASH by regulating gene expression This study investigated guinea pigs—a species that, like humans, depends on vitC in the diet—as a model of pediatric MASH, examining the effects of poor VitC status on MASH hallmarks and global DNA methylation levels. Methods: Sixty-two juvenile guinea pigs were exposed to a high-fat diet for 16 weeks. Results: Juvenile guinea pigs exhibited hepatic histopathology representative of pediatric MASH, confirmed by portal inflammation and fibrosis. Consistent with pediatric MASH, juvenile guinea pigs displayed increased lobular and portal inflammation (p < 0.05 and p < 0.0001, respectively) but less steatosis (p < 0.001) compared to adults. Compared to the controls, the guinea pigs deprived in VitC showed lower body weight (p < 0.01), higher expression of hepatic inflammatory genes (p < 0.05), and a lower global hydroxymethylcytosine to methylcytosine ratio in the high-fat groups (p < 0.05). Conclusions: Our study validates guinea pigs as a model of pediatric MASH and suggests that VitC contributes to an altered gene expression signature through the regulation of DNA hydroxymethylation. We postulate that nutritional co-deficiencies in MASH, such as low VitC, may accelerate disease progression and deserve further attention. Full article

Naturally occurring radionuclides are ubiquitous at various levels of concentration, while exposure to ionizing radiation by humans is of global concern. Radiological health risk assessment due to the consumption of natural spring mineral water is critical for ensuring public health and safety. This study aims at investigating the radioactivity concentration levels of natural radionuclides ²²⁶Ra, ²³²Th and ⁴⁰K and the associated radiological health risk in commercial natural spring bottled water in South Africa. A total of 21 of the most-consumed bottled drinking water brands from grocery stores, were analysed using the HPGe gamma detector. The results indicate that the range of radioactivity concentrations is from 1.060 ± 0.067 to 2.571 ± 0.143 BqL⁻¹, with a mean of 1.766 ± 0.399 BqL⁻¹ for ²²⁶Ra; 1.736 ± 0.112 to 7.807 ± 0.099 BqL⁻¹, with a mean of 3.688 ± 1.371 BqL⁻¹ for ²³²Th and 149.000 ± 38.480 to 242.900 ± 59.700 BqL⁻¹ with a mean of 220.229 ± 22.297 BqL⁻¹ for ⁴⁰K. The potential radiological health risks evaluated show mean values for Ra_eq, D_Ab, AEID and AGED as 23.976 ± 0.446 BqL⁻¹, 12.232 ± 1.445 nGyh⁻¹, 0.060 ± 0.007 mSvy⁻¹ and 0.090 ± 0.027 mSvy⁻¹, respectively. The radiation dose based on age group is in the order of infants (≤1 year) > teenagers (12–17 years) > children (1–12 years) > adults (>17 years). The activity concentrations of radionuclides in bottled water are ranked in the order of ⁴⁰K > ²³²Th > ²²⁶Ra, with ²³²Th contributing the highest radiation dose, consistent with findings reported in previous studies. The findings reveal that the activity concentration levels and estimated radiological health risks are within the permissible limits set by UNSCEAR guidelines. Therefore, the consumption of bottled water is radiologically safe. However, the findings also suggest that 12 out of 1000 individuals may suffer cancer fatality, while 6 out of 1 million individuals may experience hereditary effects over their lifetime from the consumption of bottled water. Regular monitoring and stringent regulatory controls are recommended to ensure the radiological safety of bottled drinking water in South Africa. Full article