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Search Results (1,364)

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19 pages, 2159 KiB  
Article
Correlation Between Pain Intensity and Trunk Sway in Seated Posture Among Office Workers with Chronic Spinal Pain: A Pilot Field-Based Study
by Eduarda Oliosi, Afonso Caetano Júlio, Luís Silva, Phillip Probst, João Paulo Vilas-Boas, Ana Rita Pinheiro and Hugo Gamboa
Sensors 2025, 25(5), 1583; https://doi.org/10.3390/s25051583 - 5 Mar 2025
Abstract
This pilot study examines the relationship between pain intensity and trunk sitting postural control in 10 office workers with chronic spinal pain, using field-based real-time inertial sensors. Pain intensity was assessed with the Numeric Pain Rating Scale (NPRS) before and after work across [...] Read more.
This pilot study examines the relationship between pain intensity and trunk sitting postural control in 10 office workers with chronic spinal pain, using field-based real-time inertial sensors. Pain intensity was assessed with the Numeric Pain Rating Scale (NPRS) before and after work across three non-consecutive workdays, while postural control was evaluated through estimated center of pressure (COP) displacements. Linear and nonlinear metrics, including sway range, velocity, the Hurst exponent, and sample entropy, were derived from the estimated COP time series. Pearson correlation coefficients (r) and corresponding p-values were used to analyze the relationship between pain intensity and postural control. Significant correlations, though limited to specific metrics, were found (r = −0.860 to 0.855; p < 0.05), suggesting that higher pain intensity may be correlated with reduced postural variability. These findings provide preliminary insights into the potential link between pain intensity and postural control. Understanding trunk posture dynamics could inform the development of targeted ergonomic interventions to reduce musculoskeletal stress and improve sitting comfort in office environments. Full article
(This article belongs to the Special Issue Sensors for Physiological Monitoring and Digital Health)
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<p>Interface for assessing pain location and intensity.</p>
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<p>Illustration of COP sway during seated posture.</p>
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<p>Coordinate system for smartphone-assisted postural analysis.</p>
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11 pages, 626 KiB  
Article
Reactive Balance in Adolescent Idiopathic Scoliosis: A Prospective Motion Analysis Study
by Ria Paradkar, Christina Regan, Kathie Bernhardt, Kenton R. Kaufman, Todd A. Milbrandt and A. Noelle Larson
J. Clin. Med. 2025, 14(5), 1715; https://doi.org/10.3390/jcm14051715 - 4 Mar 2025
Viewed by 86
Abstract
Background/Objectives: Traditional fusion leads to a loss of spine mobility across the fused vertebrae. Vertebral body tethering (VBT) was developed with the goal of increasing flexibility and maintaining some spinal mobility. However, it is not known if the additional mobility leads to [...] Read more.
Background/Objectives: Traditional fusion leads to a loss of spine mobility across the fused vertebrae. Vertebral body tethering (VBT) was developed with the goal of increasing flexibility and maintaining some spinal mobility. However, it is not known if the additional mobility leads to significant functional improvement. This prospective motion analysis study evaluates functional outcomes, specifically gait stability, in pre-operative, post-fusion, and post-VBT patients by using postural perturbations on a treadmill. Methods: Overall, 79 subjects underwent a computer-controlled treadmill study with postural perturbations, which simulated trips and slips. The subjects were harnessed for safety. Overall, 21 subjects were healthy controls, 18 patients were at least one-year post-VBT, 15 patients were at least one-year post-fusion, and 25 were pre-operative scoliosis patients. Subject weight, height, and treadmill acceleration were recorded and used to determine anteroposterior single (ASSTs, PSSTs) and multiple (AMSTs, PMSTs) stepping thresholds to describe the maximum torque a patient could withstand before failing to recover from the simulated trip. Independent t-tests were run to compare groups under the advice of a master statistician with expertise in orthopedic surgery. Results: Pre-operative scoliosis patients had lower PSSTs than healthy controls (uncorrected p = 0.036). No significant differences were observed between pre-operative and post-operative groups for both fusion and VBT. There was no significant difference in ASST, AMST, or PMST between any of the groups. Conclusions: The lower PSST in pre-operative scoliosis patients compared to healthy controls may reflect impaired reactive balance and potentially increased fall risk. Interestingly, there was no significant difference in reactive balance measures between pre-operative and post-operative scoliosis patients or between post-fusion and post-VBT patients. Full article
(This article belongs to the Section Orthopedics)
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<p>Computer-controlled treadmill simulation setup with patient in harness.</p>
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<p>Control vs. pre-op scoliosis posterior single-stepping threshold.</p>
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12 pages, 269 KiB  
Review
Review: Botulinum Toxin for Treatment of Focal Limb Dystonia
by Emma H. Kaplan, Michele Vecchio and David M. Simpson
Toxins 2025, 17(3), 122; https://doi.org/10.3390/toxins17030122 - 4 Mar 2025
Viewed by 51
Abstract
Focal limb dystonias (FLDs) are abnormal postures and muscle contractions in an arm or leg that can occur in the setting of specific activities or without any stimulus. This pathology can have a profound impact on quality of life and potentially limit work [...] Read more.
Focal limb dystonias (FLDs) are abnormal postures and muscle contractions in an arm or leg that can occur in the setting of specific activities or without any stimulus. This pathology can have a profound impact on quality of life and potentially limit work in those whose dystonias are brought on by activities related to their occupations. Botulinum toxin (BoNT) is approved for use in the United States by the Food and Drug Administration for several indications, including cervical dystonia and blepharospasm, but not for FLD. Despite this limitation, BoNT is frequently used clinically for FLD, generally with individualized dosing based on patient need and clinician expertise. Various methods exist for targeting treatment to the specific affected muscles and assessing the benefit of treatment. Small clinical trials have demonstrated the efficacy of BoNT, but larger controlled studies are needed. Full article
20 pages, 6759 KiB  
Article
Structural and Experimental Study of a Multi-Finger Synergistic Adaptive Humanoid Dexterous Hand
by Shengke Cao, Guanjun Bao, Lufeng Pan, Bangchu Yang and Xuanyi Zhou
Biomimetics 2025, 10(3), 155; https://doi.org/10.3390/biomimetics10030155 - 3 Mar 2025
Viewed by 136
Abstract
As the end-effector of a humanoid robot, the dexterous hand plays a crucial role in the process of robot execution. However, due to the complicated and delicate structure of the human hand, it is difficult to replicate human hand functionality, balancing structural complexity, [...] Read more.
As the end-effector of a humanoid robot, the dexterous hand plays a crucial role in the process of robot execution. However, due to the complicated and delicate structure of the human hand, it is difficult to replicate human hand functionality, balancing structural complexity, and cost. To address the problem, the article introduces the design and development of a multi-finger synergistic adaptive humanoid dexterous hand with underactuation flexible articulated fingers and integrated pressure sensors. The proposed hand achieves force feedback control, minimizes actuator use while enabling diverse grasping postures, and demonstrates the capability to handle everyday objects. It combines advanced bionics with innovative design to optimize flexibility, ease of manufacturing, and cost-effectiveness. Full article
(This article belongs to the Special Issue Bionic Wearable Robotics and Intelligent Assistive Technologies)
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<p>Scheme of the underactuated humanoid hand.</p>
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<p>Modules and tendons distribution of the underactuated humanoid hand.</p>
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<p>Exploded view of the finger model.</p>
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<p>Design of moving pulley. (<b>a</b>) Exploded view of the moving pulley model. (<b>b</b>) Top view of assembled moving pulley. (<b>c</b>) Motion trajectory of the pulley in the palm.</p>
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<p>Modeling of the movable pulley.</p>
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<p>The universal relationship between force transmission ratio and tendon angles for movable pulley.</p>
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<p>The relationship between force transmission ratio and symmetrical tendon angles for movable pulley.</p>
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<p>Structure design of the wrist.</p>
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<p>Structure design of the forearm.</p>
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<p>The outline of the circuit.</p>
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<p>Calibration curve and fitting curve of force sensor.</p>
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<p>Geometric diagram of the index finger.</p>
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<p>Static equilibrium diagram of the index finger in a bent state.</p>
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<p>Motion trajectory of index fingertip.</p>
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<p>Test of grasping posture. (<b>a</b>) Orange. (<b>b</b>) Egg. (<b>c</b>) Pen. (<b>d</b>) Tube. (<b>e</b>) Plastic bottle. (<b>f</b>) Spectacle case. (<b>g</b>) Medicine bottle. (<b>h</b>) Adhesive tape. (<b>i</b>) Pen. (<b>j</b>) Ruler. (<b>k</b>) Student card.</p>
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<p>Grasping process. (<b>a</b>) Lifting tennis. (<b>b</b>) Lifting peach. (<b>c</b>) Lifting shell. (<b>d</b>) Lifting card. (<b>e</b>) Lifting sprinkling bottle.</p>
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<p>Test of passive grasping force.</p>
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<p>Test of active grasping force.</p>
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<p>Test of grab–weight Ratio.</p>
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12 pages, 1893 KiB  
Article
The Modified Broström Procedure with Suture-Tape Augmentation for Chronic Lateral Ankle Instability
by Byung-Ki Cho and Sung-Hoo Kim
J. Clin. Med. 2025, 14(5), 1683; https://doi.org/10.3390/jcm14051683 - 2 Mar 2025
Viewed by 146
Abstract
Background/Objectives: As a representative anatomic ankle ligament repair technique, the Broström procedure continues to be modified to reach better clinical outcomes, superior mechanical stability, early rehabilitation, and minimal risk of recurrent instability. This study aimed to evaluate the intermediate-term clinical outcomes after [...] Read more.
Background/Objectives: As a representative anatomic ankle ligament repair technique, the Broström procedure continues to be modified to reach better clinical outcomes, superior mechanical stability, early rehabilitation, and minimal risk of recurrent instability. This study aimed to evaluate the intermediate-term clinical outcomes after the modified Broström procedure (MBP) with suture-tape augmentation for chronic lateral ankle instability. Methods: Ninety-four patients with chronic lateral ankle instability were followed for ≥3 years after MBP augmented with suture tape. The patient-reported clinical outcomes were evaluated with the Foot and Ankle Outcome Score (FAOS) and the Foot and Ankle Ability Measure (FAAM). The changes in mechanical ankle stability were evaluated with physical examination and periodic stress radiography. The changes in static and dynamic postural control ability were assessed with the single-leg stance test and Biodex posturography. Results: FAOS and FAAM scores significantly improved from preoperative means of 52.6 and 54.2 points to 91.8 and 90.5 points at final follow-up, respectively (p < 0.001). Talar tilt angle and anterior talar translation significantly improved from preoperative means of 15.4° and 14.3 mm to 2.7° and 4.5 mm at final follow-up, respectively (p < 0.001). Two patients (2.1%) complained of a recurrence of mechanical and functional instability. One patient (1.1%) showed non-specific inflammation related to a suture tape. Balance retention time significantly improved from a preoperative mean of 3.7 to 6.4 s at final follow-up (p < 0.001), with a non-significant side-to-side difference. The overall stability index significantly improved from a preoperative mean of 3.7 to 1.9 at final follow-up (p < 0.001), with a significant side-to-side difference. Conclusions: The MBP augmented with suture tape appears to be an effective surgical technique for chronic lateral ankle instability. Through anatomic repair of attenuated ankle ligaments and suture-tape augmentation, this modified procedure can provide reliable stability and minimal risk of recurrent instability. In addition, static and dynamic postural control ability may be improved through continuous proprioceptive-oriented rehabilitation following surgery. Full article
(This article belongs to the Special Issue Clinical Advancements in Foot and Ankle Surgery)
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<p>Flowchart diagram of this study.</p>
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<p>(<b>A</b>) Intraoperative photograph showing the attenuated lateral ligamentous tissue in a 34-year-old male patient. (<b>B</b>) Following fixation of two 3.5 mm metallic suture anchors into the lateral malleolus, FiberWire<sup>®</sup> suture tape is secured using a 3.5 mm SwiveLock<sup>®</sup> biocomposite suture anchor.</p>
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<p>Intraoperative photographs showing (<b>A</b>) passage of suture tape outside of the fibular periosteum, (<b>B</b>) imbrication with horizontal mattress suture technique, and (<b>C</b>) repair of the lateral ligaments and capsule.</p>
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<p>(<b>A</b>,<b>B</b>) Intraoperative fluoroscopic images show a proper entry-point of suture tape using temporary guidewire fixation. (<b>C</b>) The repaired lateral ligaments are augmented with suture tape which is fixed into the talar neck using a 4.75 mm SwiveLock<sup>®</sup> biocomposite suture anchor.</p>
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19 pages, 9800 KiB  
Article
Assist-as-Needed Controller of a Rehabilitation Exoskeleton for Upper-Limb Natural Movements
by Shuo Pei, Jiajia Wang, Chenghua Tian, Xibin Li, Bingqi Guo, Junlong Guo and Yufeng Yao
Appl. Sci. 2025, 15(5), 2644; https://doi.org/10.3390/app15052644 - 28 Feb 2025
Viewed by 228
Abstract
Active patient participation in the rehabilitation process after stroke has been shown to accelerate neural remodeling. The control framework of rehabilitation robots should provide appropriate assistive forces to users. An assist-as-needed (AAN) control method is proposed to help users to move upper limbs [...] Read more.
Active patient participation in the rehabilitation process after stroke has been shown to accelerate neural remodeling. The control framework of rehabilitation robots should provide appropriate assistive forces to users. An assist-as-needed (AAN) control method is proposed to help users to move upper limbs in the workspace freely, and to control the exoskeleton to provide assistance. The method is based on zero moment control (ZMC), helping the user achieve robotic traction with minimal interaction force. Based on the posture of the upper arm and forearm, an AAN controller can modify assistive forces at two human–robot-interaction (HRI) points along the direction opposite to gravity. A shoulder motion prediction model is proposed to enable the exoskeleton to mimic the user’s upper limb natural movements. In order to improve the transparency during rehabilitation training, a nonlinear numerical friction model based on the Stribeck friction model is developed. A healthy adult male was recruited to perform various activities of daily living (ADL) tests to assess the effectiveness of the controllers. The experimental results show that the proposed ZMC controller has high HRI transparency and can control the exoskeleton to complete a wide range of upper limb movements, and the maximum interaction force and torque can be captured within −7.76 N and 4.58 Nm, respectively. The AAN controller can provide appropriate assistance in the desired direction, and the exoskeleton maintains kinematic synchronization with the user’s shoulder during shoulder girdle movement. Full article
(This article belongs to the Special Issue Emerging Technologies for Assistive Robotics)
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<p>(<b>a</b>) FREE exoskeleton prototype. (<b>b</b>) FREE simplified model.</p>
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<p>ROM of shoulder ball-and-socket joint of a healthy adult male. The blue area represents the GH workspace.</p>
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<p>Friction torque of J3 at different velocities.</p>
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<p>The scapulohumeral joint and humerus are reduced to vectors, and the direction is described by the spherical coordinate parameter. <math display="inline"><semantics> <msub> <mi mathvariant="bold-italic">φ</mi> <mi>ed</mi> </msub> </semantics></math> and <math display="inline"><semantics> <msub> <mi mathvariant="bold-italic">φ</mi> <mi>pr</mi> </msub> </semantics></math> represent the elevation/depression inclination of the y-axis and the protraction/retraction inclination of the x-axis, respectively, around the scapulohumeral’s fixed coordinate system. <math display="inline"><semantics> <msub> <mi mathvariant="bold-italic">φ</mi> <mi>po</mi> </msub> </semantics></math> and <math display="inline"><semantics> <msub> <mi mathvariant="bold-italic">φ</mi> <mi>az</mi> </msub> </semantics></math> represent the polar and azimuthal humerus angles in the torso coordinate system. <math display="inline"><semantics> <msub> <mi>γ</mi> <mi mathvariant="normal">p</mi> </msub> </semantics></math> represents the angle between the upper arm and <math display="inline"><semantics> <msub> <mi mathvariant="bold-italic">u</mi> <mn>0</mn> </msub> </semantics></math>.</p>
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<p>Architecture of the control system, which consists of a high level, mid level, and low level.</p>
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<p>Torque response of J6. (<b>a</b>) Torque tracking curve. (<b>b</b>) bode diagram of amplitude of torque closed-loop. (<b>c</b>) bode diagram of phase of torque closed-loop.</p>
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<p>Comparison of three friction models. The tested joint was J2.</p>
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<p>Trajectories of the volunteers’ hands in the Cartesian coordinate system in both experimental groups. (<b>a</b>) head touching. (<b>b</b>) cleaning. The orange solid line represents hand trajectory generated by ZMC controller, the blue dashed line represents hand trajectory generated by the AAN controller.</p>
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<p>Human–robot interaction force/torque at the two connection points of the upper limb in the world coordinate system during the head-touching and cleaning tasks. The used controller is indicated at the bottom of each column. The first row represents the upper limb interaction force/torque, and the second row represents the wrist interaction force/torque. (<b>a</b>–<b>d</b>) represents upper limb sensor data during two task under two controller. (<b>e</b>–<b>h</b>) represents upper limb sensor data during two task under two controller.</p>
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<p>Joint angles of J1 and J2 in two tasks. (<b>a</b>) head touching with AAN. (<b>b</b>) cleaning with AAN.</p>
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23 pages, 1202 KiB  
Article
Balance Performance After Mild Traumatic Brain Injury in Children and Adolescents: Instrumented BESS in the Acute Situation and Over Time
by Nils K. T. Schönberg, Johanna Wagner, Korbinian Heinrich, Ida Kandler, Tobias Graf, Rieke Böddeker, Lea Zinke, Nicole Fabri, Julia Wilke, Florian Hoffmann, A. Sebastian Schröder, Anne-Sophie Holler, Alexandra Fröba-Pohl, Oliver Muensterer, Doreen Huppert, Matthias Hösl, Florian Heinen and Michaela V. Bonfert
J. Clin. Med. 2025, 14(5), 1666; https://doi.org/10.3390/jcm14051666 - 28 Feb 2025
Viewed by 287
Abstract
Background: Mild traumatic brain injury (mTBI) in the pediatric population is a significant public health concern, often associated with persistent post-concussion symptoms, including postural instability. Current tools for assessing postural control, such as the Balance Error Scoring System (BESS), lack integration with [...] Read more.
Background: Mild traumatic brain injury (mTBI) in the pediatric population is a significant public health concern, often associated with persistent post-concussion symptoms, including postural instability. Current tools for assessing postural control, such as the Balance Error Scoring System (BESS), lack integration with objective metrics. Incorporating force plate sensors into BESS assessments may enhance diagnostic accuracy and support return-to-play or sports decisions. This study evaluates postural performance in children with mTBI compared to controls using an instrumented BESS and examines recovery trajectories after mTBI. Methods: This prospective, longitudinal study included 31 children with mTBI (12.01 ± 3.28 years, 20 females) and 31 controls (12.31 ± 3.27 years, 18 females). Postural control was assessed using an instrumented BESS protocol during standing on a ground reaction force plate at three timepoints: within 72 h post injury (T1), at two weeks (T2), and three months after trauma (T3). Posturographic parameters derived from the displacement of the center of pressure included the ellipse area, path length, and mean velocity in the anterior–posterior and medio–lateral directions. Symptom burden was monitored using the Post-Concussion Symptom Inventory (PCSI). Results: The BESS total scores did not differ significantly between the groups at any timepoint. A significant reduction in BESS errors over time was observed exclusively in the two-legged stance on a soft surface (p = 0.047). The instrumented BESS revealed higher body swaying in the mTBI group compared to controls, particularly under demanding conditions. Significant between-group differences were most frequently observed in single-leg soft surface (38% of comparisons) and two-legged soft surface stances (29%). In those cases, path length and mean velocity differed between groups, respectively. Ellipse area did not show significant differences across conditions. Conclusions: An instrumented BESS has the potential to enhance the detection of subtle postural deficits in pediatric mTBI patients. Specifically, more demanding conditions with altered sensory-proprioceptive input and path length as an outcome measure should be focused on. This study underscores the need for tailored and age-appropriate objective and quantitative balance assessments to improve diagnostic precision in pediatric mTBI populations. Full article
(This article belongs to the Special Issue Traumatic Brain Injury: Current Treatment and Future Options)
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<p>Study design (figure created using diagrams.net).</p>
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<p>Significant differences between mTBI patients and controls in the posturographic assessment across the three study visits. The analysis of all of the 7 outcome measures under all of the 6 testing conditions resulted in <span class="html-italic">n</span> = 24 significant findings. Green lines mark measures that were higher in the PG than in the CG; the violet color marks measures that were lower in the PG than in the CG. Positions with lowest (blue) and highest (red) body swaying in each group are marked. For detailed data, please refer to <a href="#jcm-14-01666-t003" class="html-table">Table 3</a> (figure created using diagrams.net).</p>
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17 pages, 4431 KiB  
Article
The Development and Validation of a Novel Smartphone Application to Detect Postural Instability
by Shirin R. Hussain and W. Geoffrey Wright
Sensors 2025, 25(5), 1505; https://doi.org/10.3390/s25051505 - 28 Feb 2025
Viewed by 119
Abstract
Traditional assessments of balance and postural control often face challenges related to accessibility, cost, subjectivity, and inter-rater reliability. With advancements in technology, smartphones equipped with inertial measurement units (IMUs) are emerging as a promising tool for assessing postural control, measuring both static and [...] Read more.
Traditional assessments of balance and postural control often face challenges related to accessibility, cost, subjectivity, and inter-rater reliability. With advancements in technology, smartphones equipped with inertial measurement units (IMUs) are emerging as a promising tool for assessing postural control, measuring both static and dynamic motion. This study aimed to develop and validate a novel smartphone application by comparing it with research-grade posturography instruments, including motion capture and force plate systems to establish construct- and criterion-related validity. Twenty-two participants completed the quiet stance under varying visual (eyes open—EO; eyes closed—EC) and surface (Firm vs. Foam) conditions, with data collected from the smartphone, force plate, and motion capture systems. Intraclass correlation coefficients (ICCs) and Pearson correlation coefficients assessed the reliability and validity for all outcome measures (sway area and sway velocity). The results demonstrated reliability, with strong validity between the devices. A repeated-measures ANOVA found no significant differences between the devices. Postural outcomes revealed the significant main effects of both the visual (EO vs. EC) and surface (Firm vs. Foam) conditions. In conclusion, the study demonstrated the validity, sensitivity, and accuracy of the custom-designed smartphone app, offering the potential for bridging the gap between at-home and clinical balance assessments. Full article
(This article belongs to the Collection Sensors for Gait, Human Movement Analysis, and Health Monitoring)
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<p>(<b>a</b>) The smartphone application user interface was controlled remotely by the experimenter. (<b>b</b>) Motion capture markers were placed on the participant’s body in the anterior and posterior positions. The orange dot illustrates the marker located on top of the smartphone device, which was attached at the L5 region. (<b>c</b>) For the greatest sensitivity, the smartphone was oriented horizontally and was secured to the participant using a belted phone holder. Orientation was confirmed using Apple’s preloaded Measure application to confirm the spirit level prior to data collection.</p>
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<p>The order of testing for each participant. Firm surface and eyes open visual conditions were performed first during each data collection session. A total of twelve 30-s trials were administered to each participant.</p>
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<p>Time-series plots illustrating the postural movement data (AP sway) collected using three synchronized instruments from one representative participant tested in trials 1−6.</p>
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<p>Pearson correlation applied across the group mean postural variables: (<b>a</b>) Firm sway area; (<b>b</b>) Firm sway velocity; (<b>c</b>) Foam sway area; (<b>d</b>) Foam sway velocity.</p>
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<p>Bland–Altman plots of the mean of the measurements of the smartphone and each gold-standard instrument (motion capture and force plate) against the difference in the measurement of individual participants for the sway area (left: <b>a</b>,<b>c</b>,<b>e</b>,<b>g</b>) and sway velocity (right: <b>b</b>,<b>d</b>,<b>f</b>,<b>h</b>) for each visual and surface condition.</p>
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<p>Bland–Altman plots of the mean of the measurements of the smartphone and each gold-standard instrument (motion capture and force plate) against the difference in the measurement of individual participants for the sway area (left: <b>a</b>,<b>c</b>,<b>e</b>,<b>g</b>) and sway velocity (right: <b>b</b>,<b>d</b>,<b>f</b>,<b>h</b>) for each visual and surface condition.</p>
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<p>Comparison of synchronously collected data from the smartphone, motion capture, and force plate systems in each visual and surface condition for the postural outcome measures. Note asterisks (*) denotes statistically significant differences between visual and surface conditions.</p>
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<p>Comparison of synchronously collected data from the smartphone, motion capture, and force plate systems in each visual and surface condition for the postural outcome measures. Note asterisks (*) denotes statistically significant differences between visual and surface conditions.</p>
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18 pages, 2269 KiB  
Article
Persistence of Primitive Reflexes as Possible Predictive Factors for Progression, Prevention, and Early Rehabilitation Intervention in Idiopathic Scoliosis
by Liliana Vlădăreanu, Mădălina Gabriela Iliescu, Iulia Tania Andronache and Elena Danteș
Medicina 2025, 61(3), 427; https://doi.org/10.3390/medicina61030427 - 28 Feb 2025
Viewed by 116
Abstract
Background and objectives: Idiopathic scoliosis is a three-dimensional spinal deformity characterized by a lateral curvature exceeding 10 degrees in the frontal plane accompanied by vertebral rotation in the transverse plane. Despite extensive research on genetic and neurological factors, its etiology is uncertain. [...] Read more.
Background and objectives: Idiopathic scoliosis is a three-dimensional spinal deformity characterized by a lateral curvature exceeding 10 degrees in the frontal plane accompanied by vertebral rotation in the transverse plane. Despite extensive research on genetic and neurological factors, its etiology is uncertain. This prospective observational study aims to investigate the relation between the primitive reflexes, specifically, the asymmetric tonic neck reflex (ATNR), symmetric tonic neck reflex (STNR), and spinal Galant reflex (SGR), which play key roles in early motor development and postural control and the severity of idiopathic scoliosis (measured via the Cobb angle and the Nash–Moe rotational quota. Additionally, the study evaluated whether the retention of primitive reflexes correlates with increased progression risk over 12 months of conservative treatment. Materials and Methods: Our study cohort included 162 patients, aged 7–19 years, diagnosed with idiopathic scoliosis, who underwent clinical examination and assessment of retained primitive reflexes using standardized grading systems. Results: A total of 162 patients (95 girls, 67 boys; mean age: 12.73 ± 2.74 years) met the inclusion criteria. In 73.5% of the cases, scoliosis was detected, with the majority occurring in the dorsal region (40.1%). The mean initial Cobb angle was 13.49° ± 7.14°, with no significant change after 12 months of conservative treatment (p = 0.584). Nash–Moe rotation scores were 1 in 52.5% and 2 in 22% of the cases. Retention of the following primitive reflexes were identified at baseline: Moro (19.1%), ATNR (38.3%), STNR (44.4%), and GSR (27.8%). GSR retention significantly correlated with the Cobb angle (p = 0.011; R = 0.233). All the reflex scores decreased significantly after 12 months, but no correlation existed between the retained reflexes and scoliosis progression. Patients with a history of quadrupedal locomotion had significantly lower ATNR (p = 0.002), STNR (p < 0.001), and GSR (p = 0.017) retention. Conclusions: These findings suggest that primitive reflex testing could serve as an early screening tool in scoliosis risk stratification, being a cost-effective, non-invasive instrument for identifying at-risk children before clinically significant deformity develops. Full article
(This article belongs to the Section Sports Medicine and Sports Traumatology)
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<p>Evolution of the retained Moro reflex.</p>
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<p>Evolution of the retained ATNR.</p>
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<p>Retained STNR evolution.</p>
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<p>Retained GSR evolution.</p>
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<p>ROC curve in establishing the cut-off value for the Moro score evolution difference in scoliosis grading improvement.</p>
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<p>Correlation between initial values of the Cobb angle and the retained GSR.</p>
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<p>Correlation between initial values of the Cobb angle and the Moro score evolution difference.</p>
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<p>Correlation between initial values of the Cobb angle and the GSR score evolution difference.</p>
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<p>Comparison of initial values of the ATNR according to the existence of quadrupedal locomotion.</p>
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<p>Comparison of initial values of the STNR according to the existence of quadrupedal locomotion.</p>
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<p>Comparison of initial values of the GSR according to the existence of quadrupedal locomotion.</p>
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21 pages, 1680 KiB  
Article
Sensor-Based Assessment of Mental Fatigue Effects on Postural Stability and Multi-Sensory Integration
by Yao Sun, Yingjie Sun, Jia Zhang and Feng Ran
Sensors 2025, 25(5), 1470; https://doi.org/10.3390/s25051470 - 27 Feb 2025
Viewed by 191
Abstract
Objective: Mental fatigue (MF) induced by prolonged cognitive tasks poses significant risks to postural stability, yet its effects on multi-sensory integration remain poorly understood. Method: This study investigated how MF alters sensory reweighting and postural control in 27 healthy young males. A 45 [...] Read more.
Objective: Mental fatigue (MF) induced by prolonged cognitive tasks poses significant risks to postural stability, yet its effects on multi-sensory integration remain poorly understood. Method: This study investigated how MF alters sensory reweighting and postural control in 27 healthy young males. A 45 min incongruent Stroop task was employed to induce MF, validated via subjective Visual Analog Scale (VAS) scores and psychomotor vigilance tests. Postural stability was assessed under four sensory perturbation conditions (O-H: no interference; C-H: visual occlusion; O-S: proprioceptive perturbation; C-S: combined perturbations) using a Kistler force platform. Center of pressure (COP) signals were analyzed through time-domain metrics, sample entropy (SampEn), and Discrete Wavelet Transform (DWT) to quantify energy distributions across sensory-related frequency bands (visual: 0–0.1 Hz; vestibular: 0.1–0.39 Hz; cerebellar: 0.39–1.56 Hz; proprioceptive: 1.56–6.25 Hz). Results: MF significantly reduced proprioceptive energy contributions (p < 0.05) while increasing vestibular reliance under O-S conditions (p < 0.05). Time-domain metrics showed no significant changes in COP velocity or displacement, but SampEn decreased under closed-eye conditions (p < 0.001), indicating reduced postural adaptability. DWT analysis highlighted MF’s interaction with visual occlusion, altering cerebellar and proprioceptive energy dynamics (p < 0.01). Conclusion: These findings demonstrate that MF disrupts proprioceptive integration, prompting compensatory shifts toward vestibular and cerebellar inputs. The integration of nonlinear entropy and frequency-domain analyses advances methodological frameworks for fatigue research, offering insights into real-time sensor-based fatigue monitoring and balance rehabilitation strategies. This study underscores the hierarchical interplay of sensory systems under cognitive load and provides empirical evidence for optimizing interventions in high-risk occupational and clinical settings. Full article
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<p>Kistler dynamometer.</p>
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<p>Stroop flow diagram.</p>
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<p>Experimental flow chart.</p>
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<p>(<b>a</b>) Response time of PVT. (<b>b</b>) Subjective rating of VAS-MF. (<b>c</b>) Subjective rating of VAS-MOT. (<b>d</b>) Subjective rating of VAS-RPE. Various indicators at different stages of fatigue intervention. Note: Statistical differences in different fatigue stages are represented as * <span class="html-italic">p</span> &lt; 0.05, ** <span class="html-italic">p</span> &lt; 0.01, *** <span class="html-italic">p</span> &lt; 0.001. Pre-intervention fatigue stage is natural state (normal state), denoted as N-MF; immediately after mental fatigue intervention is fatigue state (mental fatigue state), denoted as MF; 20 min post-fatigue intervention is post-fatigue state, denoted as A-MF. ns is not significant.</p>
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<p>(<b>a</b>) Visual input frequency band. (<b>b</b>) Vestibular sensory input frequency band. (<b>c</b>) Cerebellar input frequency band. (<b>d</b>) Proprioceptive input frequency band. Proportion of energy in each sensory input frequency band before and after fatigue intervention. Note: Statistical differences in different fatigue stages are represented as * <span class="html-italic">p</span> &lt; 0.05, ** <span class="html-italic">p</span> &lt; 0.01, *** <span class="html-italic">p</span> &lt; 0.001. ns is not significant.</p>
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<p>(<b>a</b>) Visual input frequency band. (<b>b</b>) Vestibular sensory input frequency band. (<b>c</b>) Cerebellar input frequency band. (<b>d</b>) Proprioceptive input frequency band. Proportion of energy in each sensory input frequency band before and after fatigue intervention. Note: Statistical differences in different fatigue stages are represented as * <span class="html-italic">p</span> &lt; 0.05, ** <span class="html-italic">p</span> &lt; 0.01, *** <span class="html-italic">p</span> &lt; 0.001. ns is not significant.</p>
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19 pages, 858 KiB  
Article
The Impact of RObotic Assisted Rehabilitation on Trunk Control in Patients with Severe Acquired Brain Injury (ROAR-sABI)
by Letizia Castelli, Claudia Loreti, Anna Maria Malizia, Chiara Iacovelli, Sabina Renzi, Luca Fioravanti, Vincenza Amoruso, Ilaria Paolasso, Francesca Di Caro, Luca Padua and Silvia Giovannini
Appl. Sci. 2025, 15(5), 2539; https://doi.org/10.3390/app15052539 - 26 Feb 2025
Viewed by 186
Abstract
Daily activities require balance and control posture. A severe Acquired Brain Injury (sABI) disrupts movement organization, control and execution, affecting trunk control and balance. Trunk control therapy for difficult patients requires known and novel methods. This study analyzes how hunova® robotic platform [...] Read more.
Daily activities require balance and control posture. A severe Acquired Brain Injury (sABI) disrupts movement organization, control and execution, affecting trunk control and balance. Trunk control therapy for difficult patients requires known and novel methods. This study analyzes how hunova® robotic platform therapy affects sABI patients’ sitting balance and trunk control. Twenty-six sABI patients were randomized into the experimental group (HuG) that employed hunova® for trunk control in addition to traditional therapy and the control group (CoG) that received only conventional rehabilitation. Clinical assessments were performed for trunk, balance, cognitive and motor performance, disability, autonomy, quality of life, and fatigue. Both static and dynamic sitting balance and trunk control were assessed with hunova®. HuG and CoG were significant in intragroup analysis. Intergroup comparisons showed substantial differences in trunk control, affected side motor function, autonomy, quality of life, and fatigue. Only patients with HuG improved statistically in the instrumental assessment of trunk control and sitting balance. Between-group analysis showed that a statistically significant difference emerged in COP path and trunk movement. The study found effectiveness and adaptability of hunova® for trunk control rehabilitation, showing improvement in static and dynamic trunk control, motor function, autonomy, quality of life and fatigue in sABI patients. Registration: NCT05280587. Full article
(This article belongs to the Special Issue Emerging Technologies for Assistive Robotics)
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<p>Exercises of static (<b>A</b>,<b>B</b>) and dynamic macroareas (<b>C</b>,<b>D</b>). (<b>A</b>) Trunk reaching; (<b>B</b>) Trunk drawing; (<b>C</b>) Pick the fruit; (<b>D</b>) Elastic ping pong.</p>
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<p>Comparison of results from T0 and T1 between HuG and CoG in trunk control (TIS), motor performance (MI-LL AFF), autonomy (mBI), self-perceived quality of life (EQ-5D_VAS) and fatigue (MFIS). Improved TIS score (<span class="html-italic">p</span> = 0.013), MI-LL AFF score (<span class="html-italic">p</span> = 0.046), mBI score (<span class="html-italic">p</span> = 0.001) and EQ-5D_VAS (<span class="html-italic">p</span> = 0.011) are indicative of improved trunk control, motor performance with affected side, autonomy and quality of life. The decrease in MFIS physical score (<span class="html-italic">p</span> = 0.002) and MFIS total score (<span class="html-italic">p</span> = 0.017) is indicative of the improvement in the level of fatigue, especially motor fatigue.</p>
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20 pages, 2016 KiB  
Article
Exploring Growth-Stage Variations in Home Use of Positioning and Mobility Assistive Technology for Children with GMFCS IV Cerebral Palsy: Parental Insights and Challenges
by Hsin-Yi Kathy Cheng, Shun-Yin Hu, Yan-Ying Ju and Yu-Chun Yu
Bioengineering 2025, 12(3), 241; https://doi.org/10.3390/bioengineering12030241 - 26 Feb 2025
Viewed by 249
Abstract
This study examines how the use of postural and mobility devices evolves in home environments for children with GMFCS IV cerebral palsy, focusing on parents’ perspectives on benefits, outcomes, and challenges. As children grow, changes in muscle strength, motor function, and daily activity [...] Read more.
This study examines how the use of postural and mobility devices evolves in home environments for children with GMFCS IV cerebral palsy, focusing on parents’ perspectives on benefits, outcomes, and challenges. As children grow, changes in muscle strength, motor function, and daily activity demands necessitate adjustments in assistive devices to maintain mobility and postural support. Data from 10 parents, collected through descriptive statistics and qualitative interviews, covered device types, usage patterns, and family impacts across developmental stages from preschool to adulthood. Device needs shift significantly with growth, transitioning from early gait trainers and postural support devices to advanced mobility devices, such as power wheelchairs, which become essential in adulthood. Parents reported positive outcomes, including improved emotional well-being, social participation, and independent mobility, alongside reduced caregiving burdens. However, challenges persist, including financial constraints, frequent device replacements, and limited training for users and caregivers. These insights highlight the need for more adaptable device designs and enhanced family-centered support programs to better assist caregivers in managing device transitions. This study addresses a gap by exploring the real-world outcomes of home-based device use, providing data and parental insights to inform device design, clinical practices, and family-centered support programs. Future research should focus on enhancing device functionality, customization, and accessibility to improve quality of life and promote greater independence for individuals with cerebral palsy. Full article
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<p>Research flowchart.</p>
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<p>Home assistive device usage across four developmental stages: (<b>a</b>) preschool, (<b>b</b>) elementary school, (<b>c</b>) secondary school, and (<b>d</b>) postsecondary education.</p>
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<p>Home assistive device usage across four developmental stages: (<b>a</b>) preschool, (<b>b</b>) elementary school, (<b>c</b>) secondary school, and (<b>d</b>) postsecondary education.</p>
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<p>Heatmap of perceived benefits of assistive devices on functional performance.</p>
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<p>Effect size matrix for feeding and eating. *: statistically significant difference.</p>
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<p>Effect size matrix for joint deformity prevention. *: statistically significant difference.</p>
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<p>Effect size matrix for mobility. *: statistically significant difference.</p>
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<p>Effect size matrix for participation and social adaptation. *: statistically significant difference.</p>
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Review
The Role of Virtual Reality on Parkinson’s Disease Management: A Bibliometric and Content Analysis
by Qiang Wu, Mengli Qiu, Xiaomei Liu, WanJiaAaron He, Ting Yang and Chengsen Jia
Sensors 2025, 25(5), 1432; https://doi.org/10.3390/s25051432 - 26 Feb 2025
Viewed by 251
Abstract
The management of Parkinson’s disease (PD) has increasingly focused on innovative technologies, particularly virtual reality (VR), which has emerged as a significant tool for addressing neurological disorders. This bibliometric analysis summarizes current research trends and hotspots regarding VR applications in PD management. A [...] Read more.
The management of Parkinson’s disease (PD) has increasingly focused on innovative technologies, particularly virtual reality (VR), which has emerged as a significant tool for addressing neurological disorders. This bibliometric analysis summarizes current research trends and hotspots regarding VR applications in PD management. A comprehensive search of the Science Citation Index Expanded (SCIE) within the Web of Science Core Collection (WoSCC) identified 475 publications from 2000 to 2024. Key findings indicate a substantial increase in publication output, especially after 2013, driven by technological advancements and investments from major IT companies. Prominent research institutions and scholars from Australia, Israel, Italy, and Spain have led this field, exploring various VR applications for PD patients. The focus of VR therapy research has evolved from primarily addressing freezing of gait (FOG) to a broader range of functional impairments, including balance, postural control, upper limb motor, and cognitive function. This study provides valuable insights into the evolving landscape of clinical research on VR in PD management, highlighting global trends and potential areas for future investigation and application of VR therapies. Full article
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<p>Flow chart of the bibliometric search and analysis process.</p>
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<p>Trend of publication outputs on VR for PD management. The equation shown in the figure represents the results of the exponential regression for annual publication outputs over the past three decades.</p>
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<p>The top prolific countries and international collaboration network on VR for PD management research. (<b>A</b>) The number of publications, total citations, and citations per paper in the top 12 countries. (<b>B</b>) The cooperative network visualization map of countries.</p>
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<p>The top active institutions and the inter-institutional collaboration network on VR for PD management research. (<b>A</b>) The number of publications, total citations, and citations per paper in the top 14 institutions. (<b>B</b>) The cooperative network visualization map of institutions.</p>
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<p>The top active authors and the collaboration network on VR for PD research. (<b>A</b>) The three-dimensional plots over the authors, their affiliations, and research directions. (<b>B</b>) Collaboration networks between authors. (<b>C</b>) Top 14 authors in terms of number of documents with their productivity over the time.</p>
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<p>The related information of Bradford’s Law applied to the journals in this area.</p>
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<p>Analysis of keywords on VR for PD management field. (<b>A</b>) The main 30 keywords and frequency. (<b>B</b>) The keyword co-occurrence network map. (<b>C</b>) The keyword co-occurrence cluster map. (<b>D</b>) The top 19 keywords with the strongest citation bursts. The red line represents the period during which the keyword experienced a burst.</p>
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11 pages, 981 KiB  
Article
Acute Effects of a Single Whole-Body Vibration Session on Mobility and Postural Control in Community-Dwelling Older Adults: A Randomized Clinical Trial
by Gustavo Christofoletti, Azriel Cancian Nepomuceno de Almeida, Camilly Lorentz, Sidney Afonso Sobrinho, Renata Terra de Oliveira and Suzi Rosa Miziara Barbosa
J. Funct. Morphol. Kinesiol. 2025, 10(1), 75; https://doi.org/10.3390/jfmk10010075 - 24 Feb 2025
Viewed by 123
Abstract
Background: Whole-body vibration is a modality of exercise that uses high-frequency mechanical stimuli to enhance motor functions. Previous studies have demonstrated benefits of whole-body vibration in older adults. However, prolonged use of this modality of exercise may be detrimental to certain conditions. Objectives [...] Read more.
Background: Whole-body vibration is a modality of exercise that uses high-frequency mechanical stimuli to enhance motor functions. Previous studies have demonstrated benefits of whole-body vibration in older adults. However, prolonged use of this modality of exercise may be detrimental to certain conditions. Objectives: to verify the acute effects of a single whole-body vibration session on mobility and postural control in community-dwelling older adults. Methods: In this two-arm, single-blind clinical trial, fifty-two participants were randomly allocated to either the experimental (subject to a single whole-body vibration session with a vibration amplitude of 2 mm and a frequency of 40 Hz) or placebo group. The exercise sessions were conducted using a tri-planar vibration platform. The tri-plane plates were adjusted to vibrate up and down, side to side, and front to back. The assessments included mobility and postural control tests. Repeated-measures analyses of variance were performed to examine the main effect of group (experimental vs. placebo), time (baseline vs. after the intervention), and group × time interaction effect. Significance was set at 5%. Results: Compared with the placebo group, participants who underwent whole-body vibration showed positive outcomes in terms of mobility (p = 0.014, effect size: 0.115). Contrastingly, no significant differences were observed between the groups in terms of postural control (p > 0.05). Conclusions: Benefits of a single whole-body vibration session were observed on mobility. Using whole-body vibration to improve postural control may require additional sessions. Contraindications typical of aging should be taken into account. Full article
(This article belongs to the Special Issue Biomechanics and Neuromuscular Control of Gait and Posture)
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<p>Flow diagram of the study.</p>
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<p>Specific model demonstrating the experimental (<b>a</b>) and the placebo (<b>b</b>) exercises.</p>
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21 pages, 3808 KiB  
Article
Posture Control of Hydraulic Flexible Second-Order Manipulators Based on Adaptive Integral Terminal Variable-Structure Predictive Method
by Jianliang Xu, Zhen Sui and Feng Xu
Sensors 2025, 25(5), 1351; https://doi.org/10.3390/s25051351 - 22 Feb 2025
Viewed by 340
Abstract
As operational scenarios become more complex and task demands intensify, the requirements for the intelligence and automation of manipulators in industry are increasing. This work investigates the challenge of posture tracking control for hydraulic flexible manipulators by proposing a discrete-time integral terminal sliding [...] Read more.
As operational scenarios become more complex and task demands intensify, the requirements for the intelligence and automation of manipulators in industry are increasing. This work investigates the challenge of posture tracking control for hydraulic flexible manipulators by proposing a discrete-time integral terminal sliding mode predictive control (DITSMPC) method. First, the proposed method develops a second-order dynamic model of the manipulator using the Lagrangian dynamic strategy. Second, a discrete-time sliding mode control (SMC) law based on an adaptive switching term is designed to achieve high-precision tracking control of the system. Finally, to weaken the influence of SMC buffeting on the manipulator system, the predictive time domain function is integrated into the proposed SMC law, and the delay estimation of the unknown term in the manipulator system is carried out. The DITSMPC scheme is derived and its convergence is proven. Simulation experiments comparing the DITSMPC scheme with the classical discrete-time SMC method demonstrate that the proposed scheme results in smooth torque changes in each joint of the manipulator, with the integral of torque variations being 5.22×103. The trajectory tracking errors for each joint remain within ±0.0025 rad, all of which are smaller than those of the classical scheme. Full article
(This article belongs to the Special Issue Dynamics and Control System Design for Robot Manipulation)
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<p>Two-joint manipulator.</p>
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<p>DITSMPC for second-order manipulator.</p>
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<p>Two-joint manipulator.</p>
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<p>The difference in the control effect under the three methods (tracking). (<b>a</b>) Joint 1 tracking, (<b>b</b>) Joint 2 tracking.</p>
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<p>The trajectory tracking error of DITSMPC. (<b>a</b>) Joint 1, (<b>b</b>) Joint 2.</p>
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<p>The trajectory tracking error of ADITSMC. (<b>a</b>) Joint 1, (<b>b</b>) Joint 2.</p>
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<p>The trajectory tracking error of DITSMC. (<b>a</b>) Joint 1, (<b>b</b>) Joint 2.</p>
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<p>The control input of DITSMPC. (<b>a</b>) Joint 1, (<b>b</b>) Joint 2.</p>
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<p>The control input of ADITSMC. (<b>a</b>) Joint 1, (<b>b</b>) Joint 2.</p>
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<p>The control input of DITSMC. (<b>a</b>) Joint 1, (<b>b</b>) Joint 2.</p>
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<p>The tracking effect of the DITSMPC method and its error for Joint 1 under complex target trajectory conditions. (<b>a</b>) Tracking situation, (<b>b</b>) error.</p>
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<p>The tracking effect of the DITSMPC method and its error for Joint 2 under complex target trajectory conditions. (<b>a</b>) Tracking situation, (<b>b</b>) error.</p>
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<p>The difference in the control effect under different parameters (tracking). (<b>a</b>) Joint 1 tracking, (<b>b</b>) Joint 2 tracking.</p>
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<p>The difference in the control effect under different parameters (tracking error). (<b>a</b>) Joint 1, (<b>b</b>) Joint 2.</p>
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