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Search Results (266)

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Keywords = point-of-interest recommendation

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28 pages, 360 KiB  
Article
Dietary Habits of Pregnant Women in Spain: The Role of Nutrition Education in Midwife Consultations
by M. Josefa Olloqui-Mundet, Marta Palma-Morales, M. Carmen Cantarell-González, M. Mar Cavia, Sara R. Alonso-Torre, Olga Ocón-Hernández, Celia Rodríguez-Pérez and Celia Carrillo
Nutrients 2025, 17(1), 120; https://doi.org/10.3390/nu17010120 - 30 Dec 2024
Viewed by 433
Abstract
Background & Objectives: Correct nutrition during pregnancy is key to guaranteeing success at this stage of a woman’s life, and nutritional education is the fundamental tool for achieving this. Studies carried out in different countries indicate that pregnant women do not comply with [...] Read more.
Background & Objectives: Correct nutrition during pregnancy is key to guaranteeing success at this stage of a woman’s life, and nutritional education is the fundamental tool for achieving this. Studies carried out in different countries indicate that pregnant women do not comply with dietary and nutritional recommendations. Given the lack of evidence available in Spain and the importance of this knowledge to be able to assess the need for nutritional intervention in this group, the aim of this study focused on the current status of the issue in Spain: the quality of the diet of Spanish pregnant women and its conditioning factors. Methods: Two representative regions of the country were selected, one located in the north of Spain (Burgos) and the other in the south (Granada), and a descriptive, cross-sectional observational study (sample size: 771) was carried out using a questionnaire administered at the University Hospital of Burgos and the Hospital Clínico San Cecilio in Granada, which had previously been subjected to a process of evaluation by expert judgement. Results: Pregnant women presented an adequate diet quality (8.0 ± 2.0), according to the questionnaire used, despite their poor knowledge of food and nutrition (4.9 ± 1.6 out of 10). However, deficiencies were detected in the consumption of very interesting food groups from a nutritional point of view, such as legumes, nuts and fish (just 29.4%, 37.6% and 24.8% of the pregnant women met the recommendations, respectively) and insufficient physical exercise. The eating habits of pregnant women depend on their age, their country of origin, their level of education, their pre-pregnancy BMI, the knowledge acquired during pregnancy and the degree to which they put into practice the advice received from their midwife. Most pregnant women do not change their habits during pregnancy, although there are positive trends in this respect. Conclusion: The quality of the diet of the Spanish pregnant women surveyed, and their level of physical activity, could be improved by enhancing the nutritional education they receive during this stage of life. The role of the dietician in this respect, as part of multidisciplinary teams, should be the basis for future research. Full article
(This article belongs to the Special Issue Food Habits, Nutritional Knowledge, and Nutrition Education)
23 pages, 2328 KiB  
Article
Barriers Affecting Promotion of Active Transportation: A Study on Pedestrian and Bicycle Network Connectivity in Melbourne’s West
by Isaac Oyeyemi Olayode, Hing-Wah Chau and Elmira Jamei
Land 2025, 14(1), 47; https://doi.org/10.3390/land14010047 - 29 Dec 2024
Viewed by 484
Abstract
In the last few decades, the promotion of active transport has been a viable solution recommended by transportation researchers, urban planners, and policymakers to reduce traffic congestion and improve public health in cities. To encourage active transport, it is important for cities to [...] Read more.
In the last few decades, the promotion of active transport has been a viable solution recommended by transportation researchers, urban planners, and policymakers to reduce traffic congestion and improve public health in cities. To encourage active transport, it is important for cities to provide safe and accessible infrastructure for pedestrians and cyclists, as well as incentives for individuals to choose active modes of transportation over private vehicles. In this research, we focused on the suburb of Point Cook, located within the City of Wyndham in Melbourne’s west, owing to its rising human population and private vehicle ownership. The primary aim of this research is to examine the barriers in the interconnectivity of active transport networks for pedestrians and cyclists and to determine the segments of the transportation network that are not accessible to Point Cook residents. Our methodology is enshrined in the use of Social Pinpoint, which is an online interactive survey platform, and ground surveys (face-to-face interviews). In our assessment of the suburb of Point Cook, we utilised the concept of 20-min neighbourhoods to evaluate the accessibility of many important places within an 800-metre walking distance from residents’ homes. Based on our online interactive survey findings, approximately one-third of the individuals engaged in regular walking, with a frequency ranging from once a day to once every two days. One-third of the participants engaged in walking trips once or twice a week, whereas the remaining two-thirds conducted walking trips less frequently than once a week. Almost 89% of the participants expressed varying levels of interest in increasing their walking frequency. The findings showed that improving pedestrian and cycling networks that are easily accessible, well-integrated, inclusive, and safe is a prerequisite for achieving active transport and create neighbourhoods in which everything is accessible within a 20-min walking distance. Full article
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<p>Principles of the 20-min neighbourhood [<a href="#B43-land-14-00047" class="html-bibr">43</a>].</p>
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<p>Boundary of Point Cook within Wyndham municipality. Reprinted with permission from ref [<a href="#B48-land-14-00047" class="html-bibr">48</a>]. Published by MDPI. Copyright© 2024 MDPI Ltd. All rights reserved.</p>
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<p>Major landmarks identified as key destinations within Point Cook based on survey outcomes from the respondents.</p>
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<p>Analysis of how often Point Cook residents take a walking trip.</p>
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<p>Reasons why Point Cook residents do not ride bicycles.</p>
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21 pages, 5557 KiB  
Article
Check-In Heterogeneous Hypergraph and Personalized Preference Transfers for Cross-City POI Recommendation Method
by Ning Wei, Yunfei Li, You Wu, Xiao Chen and Jingfeng Guo
Electronics 2024, 13(24), 4954; https://doi.org/10.3390/electronics13244954 - 16 Dec 2024
Viewed by 404
Abstract
The objective of cross-city recommendation is to suggest points-of-interest (POI) in the target city that may be of interest to users, based on their check-in records from their source city. Although significant progress has been made in studying user preference transfers, there is [...] Read more.
The objective of cross-city recommendation is to suggest points-of-interest (POI) in the target city that may be of interest to users, based on their check-in records from their source city. Although significant progress has been made in studying user preference transfers, there is a lack of research focusing on personalized user preference transfers. Furthermore, the mining of user preferences from the source city is impacted by errors and missing information. To address these challenges, this paper proposes a Check-In Heterogeneous Hypergraph and Personalized Preference Transfers for Cross-City POI Recommendation Method (CHHPPT). Firstly, a check-in heterogeneous hypergraph network is introduced in the user source city preference-mining module. This network, through Heterogeneous Hypergraph Embeddings (HHE), captures user preferences in the source city, thereby mitigating the impact of errors and missing information on user preference. Subsequently, in the user-personalized preference transfer module, a user’s transferable features are obtained through a POI aggregation network. These features are then combined with a meta-network and transfer networks to achieve user-personalized preference transfer. Finally, in the target city point-of-interest recommendation module, a POI-geographical graph is constructed using the geographical information of POI. This graph, in conjunction with category information, yields a joint embedding representation. The final recommendation is achieved by integrating the user-personalized preference transfer embeddings with the target city’s POI embeddings. Extensive experiments conducted on two real-world datasets demonstrate the effectiveness of CHHPPT in cross-city recommendation tasks. Full article
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<p>Tom’s check-in records in his hometown city A and out-of-town city B, as well as his current check-in in city C.</p>
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<p>The illustration of CHHPPT framework (an edge of the same color in a check-in heterogeneous hypergraph is a heterogeneous hyperedge).</p>
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<p>Heterogeneous Hypergraph Embedding.</p>
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<p>Example of second-order similarity.</p>
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<p>Embedding size on model performance.</p>
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<p>Effect of learning rate on model performance.</p>
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<p>Effect of recommendation performance using different loss weights <math display="inline"><semantics> <msub> <mi>λ</mi> <mn>1</mn> </msub> </semantics></math>, <math display="inline"><semantics> <msub> <mi>λ</mi> <mn>2</mn> </msub> </semantics></math>, and <math display="inline"><semantics> <msub> <mi>λ</mi> <mn>3</mn> </msub> </semantics></math>.</p>
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18 pages, 2486 KiB  
Article
The Role of Road Accessibility for Tourists in the Valorization of Archaeological Resources in the Dobrogea Region, Romania
by Vasile-Gabriel Dascălu, Alexandra Grecu, Andreea Karina Gruia, Viorel Mihăilă and Cristian Constantin Drăghici
Sustainability 2024, 16(23), 10576; https://doi.org/10.3390/su162310576 - 3 Dec 2024
Viewed by 615
Abstract
Given that spatial accessibility to tourist resources is crucial for tourism development, this study analyzes the role of the distance between tourists and archaeological sites in the Dobrogea region of Romania. This study highlights the impact of road distance in the valorization of [...] Read more.
Given that spatial accessibility to tourist resources is crucial for tourism development, this study analyzes the role of the distance between tourists and archaeological sites in the Dobrogea region of Romania. This study highlights the impact of road distance in the valorization of the main archaeological sites in the chosen area, the results obtained providing information on the main parameters of archaeological resources in achieving tourism success. These data will be important clues in the future design of plans for the valorization of those archaeological sites not yet valorized from the tourist point of view. Spatial data modeling was performed using specific Geographic Information Systems tools, which allowed us to extract the necessary information. By corroborating the results of the geospatial analysis with the statistical ones, we were able to draw conclusions regarding the tourist behavior in the region and the decision factors of tourists in visiting the ancient or medieval ruins in Dobrogea. Our analysis shows a significant correlation between the road accessibility of archaeological sites and their tourist attractiveness, with a particular influence of their location in relation to the main tourist areas of interest in the region. The study area has a rich history that has left behind a high density of ancient fortresses, citadels, and cities, which are relatively underutilized for tourism. Heritage tourism has thus lagged behind coastal tourism, which attracts the highest number of tourists in the country. A better knowledge of the factors that favor the development of heritage tourism is needed in order to expand the region’s tourist offer. Our recommendations aim to improve the accessibility and attractiveness of these archaeological sites by investing in essential infrastructure, developing sustainable transportation policies and specific tourism facilities, and implementing a regional strategy to enhance and protect them, which will ultimately increase their contribution to local economies. Full article
(This article belongs to the Section Sustainability, Biodiversity and Conservation)
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<p>Location of the study area.</p>
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<p>The spatial relations between the analyzed archeological sites, the number of tourists, and the road network in Dobrogea.</p>
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<p>Adapted Huff’s index explained.</p>
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<p>Tourist arrivals in accommodation units located at most (a) 60 min, (b) 90 min, and (c) 120 min away from the archaeological sites/archaeological museums.</p>
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<p>The correlation between the number of visitors to archaeological sites and the number of arrivals at accommodation units.</p>
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<p>Correlation between PWD measured in time units and PWD measured in km.</p>
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24 pages, 712 KiB  
Review
A Framework for Middle Level Curriculum: A Literature Review to Support the Middle Level Education Research Special Interest Group Research Agenda
by Christopher Weiler, Steven B. Mertens, James Nagle, Stacie Pettit and Amanda Wall
Educ. Sci. 2024, 14(12), 1316; https://doi.org/10.3390/educsci14121316 - 29 Nov 2024
Viewed by 597
Abstract
This research synthesis, highlighting the middle level curriculum, was created as part of a working group within the American Education Research Association (AERA) Middle level Education Research Special Interest Group (MLER SIG) to advance middle level education research. The literature review that informed [...] Read more.
This research synthesis, highlighting the middle level curriculum, was created as part of a working group within the American Education Research Association (AERA) Middle level Education Research Special Interest Group (MLER SIG) to advance middle level education research. The literature review that informed this research synthesis included middle level-focused, peer-reviewed journal articles from 2016 to the present. Synthesis of the literature and iterative analysis led to organizing a middle level curriculum framework to inform middle level researchers, which included five focused areas for inquiry: (a) the curriculum and equity of experience and opportunity; (b) stakeholder power and the curriculum (development, implementation, and accountability); (c) goals and purposes for the curriculum; (d) teacher learning, roles, and enactment related to the curriculum; and (e) young adolescent well-being and experiences with the curriculum. Twenty-six research questions were developed to support new research in middle level curriculum; each question was cross-referenced with the five categories in the middle level curriculum framework to create a robust starting point for research questions. Recommendations for middle level research include (a) the need for more longitudinal research studies focusing on varying aspects of middle level education, (b) the need for more large-scale research studies examining the same context (e.g., school) or multiple contexts (e.g., school districts) over time, and (c) the need for the MLER SIG to initiate and support research studies addressing one or more aspects of this research agenda and include large-scale data collection and potentially external funding. Full article
(This article belongs to the Special Issue Moving Forward: Research to Guide Middle Level Education)
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<p>Stakeholder levels involved in curriculum development and implementation.</p>
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15 pages, 824 KiB  
Article
A Cohort Study Exploring HPV Vaccination Beliefs Among Oral Health Providers: Broadening the Scope of Education and Administration
by Leanne Brechtel, Larry C. Kilgore, Oluwafemifola Oyedeji, Alicia M. Mastronardi, Eric R. Carlson, Nikki B. Zite, Samantha Gregory, Jonathan Boone, Kristopher Kimball, Robert E. Heidel and Jill M. Maples
Vaccines 2024, 12(12), 1331; https://doi.org/10.3390/vaccines12121331 - 27 Nov 2024
Viewed by 484
Abstract
Background/Objectives: There is potential utility and increasing interest in engaging professionals in non-traditional vaccination settings to participate in efforts to reduce human papillomavirus (HPV)-related cancer. This study assessed the impact of a multi-disciplinary HPV educational intervention on oral health care professionals’ perceived role, [...] Read more.
Background/Objectives: There is potential utility and increasing interest in engaging professionals in non-traditional vaccination settings to participate in efforts to reduce human papillomavirus (HPV)-related cancer. This study assessed the impact of a multi-disciplinary HPV educational intervention on oral health care professionals’ perceived role, comfort level, and scope of practice in HPV-related cancer prevention efforts. Methods: The virtual educational intervention was provided by a multi-disciplinary panel of experts. Seventy-three oral health care professionals attended the educational intervention and completed a questionnaire at three time points (pre-session, immediate post-session, and at the 1-month follow-up). Data were analyzed using Friedman’s ANOVA and post-hoc analyses. Results: Respondent’s median belief that it is the role of an oral health professional to recommend the HPV vaccine increased from pre-session (Median = 3.0, IQR = 3.0–4.0) to immediate post-session (median = 4.5, IQR = 4.0–5.0), and this increase was maintained 1 month after the session (median = 4.0, IQR = 4.0–4.5; p < 0.001). Additionally, respondent’s belief that they were up-to-date on the latest guidelines for HPV vaccination also increased from pre-session to immediate post-session (p < 0.05), and this increase was maintained 1 month after the session (pre-session median = 2.0, IQR = 2.0–3.0 vs. 1-month post-session median = 4.0, IQR = 4.0–5.0; p < 0.005). Conclusions: The multi-disciplinary HPV educational intervention was well-received by oral health professionals. Data suggest the intervention had a lasting impact on their beliefs about their role, comfort level, and scope of practice relating to HPV cancer prevention. More research needs to be conducted to better understand how obstetrician-gynecologists, other obstetric care providers, and oral health communities can support each other in promoting HPV-related cancer prevention. Full article
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<p>Study flow diagram.</p>
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<p>Composite knowledge score at baseline, immediate post-intervention, and 1 month post-intervention.</p>
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<p>HPV vaccine recommendation practices at baseline and 1 month post-intervention.</p>
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18 pages, 3261 KiB  
Article
POI Recommendation Scheme Based on User Activity Patterns and Category Similarity
by Jongtae Lim, Seoheui Lee, He Li, Kyoungsoo Bok and Jaesoo Yoo
Appl. Sci. 2024, 14(23), 10997; https://doi.org/10.3390/app142310997 - 26 Nov 2024
Viewed by 574
Abstract
The utilization of location-based social networks to provide point-of-interest (POI) recommendation services has been the subject of extensive research in recent years. Various factors that can enhance the precision of POI recommendations were examined in previous studies. However, the factors of a user, [...] Read more.
The utilization of location-based social networks to provide point-of-interest (POI) recommendation services has been the subject of extensive research in recent years. Various factors that can enhance the precision of POI recommendations were examined in previous studies. However, the factors of a user, including the location and time, were not considered. In this paper, we proposed a POI recommendation scheme in which user activity patterns and the similarity of categories are considered. The proposed scheme is used to organize users based on the activity level and to take into account the characteristics of both the user and location. Furthermore, it provides personalized recommendations by considering the category similarity, time, and location data that were collected from users. We evaluated the performance of the proposed scheme and compared it with that of a currently used scheme. The proposed scheme exhibits precision that is approximately 16% greater than that of the existing scheme. Full article
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<p>Relationship of the considered factors of the existing schemes and the proposed scheme.</p>
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<p>Virtual tracking pattern employing the Voronoi diagram. The Voronoi diagram marked in red represents the diagram corresponding to the time period when the user moved along the path marked in red.</p>
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<p>Overall system configuration for the proposed scheme. SVD: singular value decomposition; POI: point of interest.</p>
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<p>Clustered user groups.</p>
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<p>Extraction of top-category pattern by using highly active users.</p>
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<p>Extraction of top-category pattern for all users.</p>
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<p>Performance evaluation for high-activity groups.</p>
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<p>Performance evaluation for low-activity groups.</p>
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<p>Performance evaluation for high-activity groups.</p>
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<p>Performance evaluation for low-activity groups.</p>
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12 pages, 675 KiB  
Article
Interpretable Embeddings for Next Point-of-Interest Recommendation via Large Language Model Question–Answering
by Jiubing Chen, Haoyu Wang, Jianxin Shang and Chaomurilige
Mathematics 2024, 12(22), 3592; https://doi.org/10.3390/math12223592 - 16 Nov 2024
Viewed by 604
Abstract
Next point-of-interest (POI) recommendation provides users with location suggestions that they may be interested in, allowing them to explore their surroundings. Existing sequence-based or graph-based POI recommendation methods have matured in capturing spatiotemporal information; however, POI recommendation methods based on large language models [...] Read more.
Next point-of-interest (POI) recommendation provides users with location suggestions that they may be interested in, allowing them to explore their surroundings. Existing sequence-based or graph-based POI recommendation methods have matured in capturing spatiotemporal information; however, POI recommendation methods based on large language models (LLMs) focus more on capturing sequential transition relationships. This raises an unexplored challenge: how to leverage LLMs to better capture geographic contextual information. To address this, we propose interpretable embeddings for next point-of-interest recommendation via large language model question–answering, named QA-POI, which transforms the POI recommendation task into obtaining interpretable embeddings via LLM prompts, followed by lightweight MLP fine-tuning. We introduce question–answer embeddings, which are generated by asking LLMs yes/no questions about the user’s trajectory sequence. By asking spatiotemporal questions about the trajectory sequence, we aim to extract as much spatiotemporal information from the LLM as possible. During training, QA-POI iteratively selects the most valuable subset of potential questions from a set of questions to prompt the LLM for the next POI recommendation. It is then fine-tuned for the next POI recommendation task using a lightweight Multi-Layer Perceptron (MLP). Extensive experiments on two datasets demonstrate the effectiveness of our approach. Full article
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<p>An example of a check-in sequence in a trajectory where the selection of candidate POIs is influenced by multiple factors, with geographical factors playing a significant role. Note that the dashed arrows denote the historical trajectory while the dotted ones stand for the potential visit of the next check-in. The numbers denote the order of check-ins.</p>
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<p>It illustrates the architecture of our proposed model. It consists of (1) a prompt template for generating input text modules, (2) a module for learning to answer yes/no question sets, (3) an MLP fine-tuning module, and (4) a prediction module. In particular, (1) is our proposed prompt template that incorporates various comprehensive factors to prompt the LLM to automatically generate questions; (2) continues to input these questions into the LLM to produce representation vectors and trims the question set based on the prediction results; (3) uses an MLP to further fine-tune the model parameters; and (4) the prediction module outputs a top-k set of potential target candidates.</p>
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<p>The performance comparison about the dimension <span class="html-italic">d</span>, the number of question <span class="html-italic">P</span>. The circles and squares denote the scores on Foursquare and Gowalla, respectively.</p>
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32 pages, 10468 KiB  
Article
Tourism Recommendation Algorithm Based on the Mobile Intelligent Connected Vehicle Service Platform
by Xiao Zhou, Rui Li, Fei Teng, Juan Pan and Taiping Zhao
Symmetry 2024, 16(11), 1431; https://doi.org/10.3390/sym16111431 - 28 Oct 2024
Viewed by 1459
Abstract
As to the problems in current tourism recommendation, this paper proposes a tourism recommendation algorithm based on the mobile ICV service platform. Firstly, the ICV service system for the Point of Interest (POI) searching and route recommendation is designed. Secondly, the recommendation service [...] Read more.
As to the problems in current tourism recommendation, this paper proposes a tourism recommendation algorithm based on the mobile ICV service platform. Firstly, the ICV service system for the Point of Interest (POI) searching and route recommendation is designed. Secondly, the recommendation service model is set up from two aspects, namely the tourism POI clustering algorithm and the tourism POI searching and route recommendation algorithm. In the aspect of symmetrical-based matching features, the clustered POIs are matched with the tourists’ interests, and the POIs in the neighborhood of the ICV dynamic locations are searched. Then, a POI recommendation algorithm based on the tourists’ interests is constructed, and the POIs that best match the symmetrical interests of the tourists within the dynamic buffer zones of ICV are confirmed. Based on the recommended POIs, the ICV guidance route algorithm is constructed. The experiment verifies the advantages of the proposed algorithm on the aspect of the POI matching tourists’ interests, algorithm stability, traveling time cost, traveling distance cost and computational complexity. As to the iterative sum and the iterative sum average of the POI matching function values, the proposed algorithm has a performance improvement of at least 20.2% and a stability improvement of at least 20.5% compared to the randomly selected POIs in matching tourists’ interests. As to the cost of the guidance routes, the proposed algorithm reduces the average cost by 19.6% compared to the other suboptimal routes. Compared with the control group algorithms, the proposed algorithm is superior in terms of route cost, with an average cost reduction of 13.8% for the output routes compared to the control group. Also, the proposed algorithm is superior in terms of route cost compared to the control group recommendation algorithms, with an average cost reduction of 11.2%. Full article
(This article belongs to the Special Issue Symmetry in Computing Algorithms and Applications)
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<p>The mobile ICV service platform for the POI searching and route recommendation. Module 1 is the urban tourism object database, Module 2 is the ICV on-board system, Module 3 is the ICV spatial accessibility and buffer zone searching system, Module 4 is the tourist interest data and POI matching module, Module 5 is the ICV terminal station and global ferrying lane.</p>
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<p>The structure and basic logic of the mobile ICV tourism recommendation algorithm model.</p>
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<p>The ICV tourism POI clustering algorithm process based on urban tourism object database. Figure (<b>a</b>) is the research domain. Figure (<b>b</b>) is the ICV on-board system. Figure (<b>c</b>) is the POI storage matrix. Figure (<b>d</b>) is the clustering objective function storage matrix. Figure (<b>e</b>) is the clustering seed points. Figure (<b>f</b>) is the output clusters.</p>
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<p>The ICV spatial accessibility and buffer zone searching algorithm process. Figure (<b>a</b>) shows a ferrying lane for the ICV moving from the starting point <math display="inline"><semantics> <mrow> <mrow> <msub> <mi>S</mi> <mi>t</mi> </msub> </mrow> </mrow> </semantics></math> to the terminal point <math display="inline"><semantics> <mrow> <mrow> <msub> <mi>T</mi> <mrow> <mi>e</mi> <mi>r</mi> </mrow> </msub> </mrow> </mrow> </semantics></math>, in which the yellow circles are the two end points, the blue circles are the end points for the sections, the green circles are the POI distributions. Figure (<b>b</b>) shows the example of the section <math display="inline"><semantics> <mrow> <mrow> <mi>S</mi> <mi>e</mi> <mi>a</mi> <mi>r</mi> <mi>c</mi> <mi>h</mi> <mo stretchy="false">(</mo> <mi>d</mi> <mo stretchy="false">(</mo> <mi>i</mi> <mo stretchy="false">)</mo> <mo>,</mo> <mi>d</mi> <mo stretchy="false">(</mo> <mi>i</mi> <mo>+</mo> <mn>1</mn> <mo stretchy="false">)</mo> <mo stretchy="false">)</mo> <mo stretchy="false">(</mo> <mi>i</mi> <mo stretchy="false">)</mo> </mrow> </mrow> </semantics></math>, in which the ICV-recorded time of the buffer zone searching is <math display="inline"><semantics> <mrow> <mrow> <mi>t</mi> <mn>1</mn> </mrow> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <mrow> <mi>t</mi> <mn>2</mn> </mrow> </mrow> </semantics></math>,…, <math display="inline"><semantics> <mrow> <mrow> <mi>t</mi> <mn>5</mn> </mrow> </mrow> </semantics></math>. Figure (<b>c</b>–<b>g</b>) show the buffer zone searching process at the time <math display="inline"><semantics> <mrow> <mrow> <mi>t</mi> <mn>1</mn> </mrow> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <mrow> <mi>t</mi> <mn>2</mn> </mrow> </mrow> </semantics></math>,…, <math display="inline"><semantics> <mrow> <mrow> <mi>t</mi> <mn>5</mn> </mrow> </mrow> </semantics></math>. In Figure (<b>a</b>), the brown line represents the ICV lane, the orange dots represent the starting point and terminal point of the ICV lane, the blue dots represent the critical nodes in the ICV lane, the green dots represent the POIs. In Figure (<b>b</b>–<b>g</b>), the green dots represent the POIs, the blue dots represent the starting point and terminal point of the ICV lane.</p>
Full article ">Figure 4 Cont.
<p>The ICV spatial accessibility and buffer zone searching algorithm process. Figure (<b>a</b>) shows a ferrying lane for the ICV moving from the starting point <math display="inline"><semantics> <mrow> <mrow> <msub> <mi>S</mi> <mi>t</mi> </msub> </mrow> </mrow> </semantics></math> to the terminal point <math display="inline"><semantics> <mrow> <mrow> <msub> <mi>T</mi> <mrow> <mi>e</mi> <mi>r</mi> </mrow> </msub> </mrow> </mrow> </semantics></math>, in which the yellow circles are the two end points, the blue circles are the end points for the sections, the green circles are the POI distributions. Figure (<b>b</b>) shows the example of the section <math display="inline"><semantics> <mrow> <mrow> <mi>S</mi> <mi>e</mi> <mi>a</mi> <mi>r</mi> <mi>c</mi> <mi>h</mi> <mo stretchy="false">(</mo> <mi>d</mi> <mo stretchy="false">(</mo> <mi>i</mi> <mo stretchy="false">)</mo> <mo>,</mo> <mi>d</mi> <mo stretchy="false">(</mo> <mi>i</mi> <mo>+</mo> <mn>1</mn> <mo stretchy="false">)</mo> <mo stretchy="false">)</mo> <mo stretchy="false">(</mo> <mi>i</mi> <mo stretchy="false">)</mo> </mrow> </mrow> </semantics></math>, in which the ICV-recorded time of the buffer zone searching is <math display="inline"><semantics> <mrow> <mrow> <mi>t</mi> <mn>1</mn> </mrow> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <mrow> <mi>t</mi> <mn>2</mn> </mrow> </mrow> </semantics></math>,…, <math display="inline"><semantics> <mrow> <mrow> <mi>t</mi> <mn>5</mn> </mrow> </mrow> </semantics></math>. Figure (<b>c</b>–<b>g</b>) show the buffer zone searching process at the time <math display="inline"><semantics> <mrow> <mrow> <mi>t</mi> <mn>1</mn> </mrow> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <mrow> <mi>t</mi> <mn>2</mn> </mrow> </mrow> </semantics></math>,…, <math display="inline"><semantics> <mrow> <mrow> <mi>t</mi> <mn>5</mn> </mrow> </mrow> </semantics></math>. In Figure (<b>a</b>), the brown line represents the ICV lane, the orange dots represent the starting point and terminal point of the ICV lane, the blue dots represent the critical nodes in the ICV lane, the green dots represent the POIs. In Figure (<b>b</b>–<b>g</b>), the green dots represent the POIs, the blue dots represent the starting point and terminal point of the ICV lane.</p>
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<p>The POI recommendation algorithm process based on tourists’ interests. Figure (<b>a</b>) is the ICV on-board system. Figure (<b>b</b>) is the expected clusters by tourists. Figure (<b>c</b>) is the cluster sequence matrix. Figure (<b>d</b>) is the output-recommended POIs in each expected cluster.</p>
Full article ">Figure 6
<p>The process to generate the dynamic starting point, the control points and the feasible route sections for the ICV in the time duration <math display="inline"><semantics> <mrow> <mrow> <mo>Δ</mo> <mi>t</mi> </mrow> </mrow> </semantics></math> based on the selected POIs within the section <math display="inline"><semantics> <mrow> <mrow> <mi>S</mi> <mi>e</mi> <mi>a</mi> <mi>r</mi> <mi>c</mi> <mi>h</mi> <mo stretchy="false">(</mo> <mi>d</mi> <mo stretchy="false">(</mo> <mi>i</mi> <mo stretchy="false">)</mo> <mo>,</mo> <mi>d</mi> <mo stretchy="false">(</mo> <mi>i</mi> <mo>+</mo> <mn>1</mn> <mo stretchy="false">)</mo> <mo stretchy="false">)</mo> <mo stretchy="false">(</mo> <mi>i</mi> <mo stretchy="false">)</mo> </mrow> </mrow> </semantics></math>. Figure (<b>a</b>–<b>f</b>) shows the searching for POI at time <math display="inline"><semantics> <mrow> <mrow> <mi>t</mi> <mn>1</mn> </mrow> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <mrow> <mi>t</mi> <mn>2</mn> </mrow> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <mrow> <mi>t</mi> <mn>3</mn> </mrow> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <mrow> <mi>t</mi> <mn>4</mn> </mrow> </mrow> </semantics></math>, <math display="inline"><semantics> <mrow> <mrow> <mi>t</mi> <mn>5</mn> </mrow> </mrow> </semantics></math> and <math display="inline"><semantics> <mrow> <mrow> <mi>t</mi> <mn>6</mn> </mrow> </mrow> </semantics></math>. The green dots represent POIs, the blue dots represent the starting point and terminal point of the ICV lane, the red dots represent the critical nodes in the ICV lane, the black dots represent the other road nodes.</p>
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<p>The process for the ICV guidance route algorithm. Figure (<b>a</b>): the initial status of route searching. Figure (<b>b</b>): the <math display="inline"><semantics> <mrow> <mrow> <msub> <mi>C</mi> <mrow> <mi>o</mi> <mi>n</mi> <mo stretchy="false">(</mo> <mn>1</mn> <mo stretchy="false">)</mo> </mrow> </msub> </mrow> </mrow> </semantics></math> is found and confirmed. Figure (<b>c</b>): the <math display="inline"><semantics> <mrow> <mrow> <msub> <mi>C</mi> <mrow> <mi>o</mi> <mi>n</mi> <mo stretchy="false">(</mo> <mn>3</mn> <mo stretchy="false">)</mo> </mrow> </msub> </mrow> </mrow> </semantics></math> is found and confirmed. Figure (<b>d</b>): the <math display="inline"><semantics> <mrow> <mrow> <msub> <mi>C</mi> <mrow> <mi>o</mi> <mi>n</mi> <mo stretchy="false">(</mo> <mn>4</mn> <mo stretchy="false">)</mo> </mrow> </msub> </mrow> </mrow> </semantics></math> is found and confirmed. Figure (<b>e</b>): the <math display="inline"><semantics> <mrow> <mrow> <mi>P</mi> <mo stretchy="false">(</mo> <mi>i</mi> <mo stretchy="false">)</mo> </mrow> </mrow> </semantics></math> is found and confirmed. Figure (<b>f</b>): the <math display="inline"><semantics> <mrow> <mrow> <msub> <mi>C</mi> <mrow> <mi>o</mi> <mi>n</mi> <mo stretchy="false">(</mo> <mn>5</mn> <mo stretchy="false">)</mo> </mrow> </msub> </mrow> </mrow> </semantics></math> is found and confirmed. Figure (<b>g</b>): the <math display="inline"><semantics> <mrow> <mrow> <msub> <mi>C</mi> <mrow> <mi>o</mi> <mi>n</mi> <mo stretchy="false">(</mo> <mn>8</mn> <mo stretchy="false">)</mo> </mrow> </msub> </mrow> </mrow> </semantics></math> is found and confirmed. Figure (<b>h</b>): the whole route is found and confirmed. The red dot and blue dot represent the starting point and terminal point of the ICV lane, the black dots represent the road nodes, the yellow dot represents the POI, the brown line represents the ICV route.</p>
Full article ">Figure 8
<p>The ICV ferrying lane and the POI distributions in the experimental space. Figure (<b>a</b>) is the distributions of the ferrying lane and the POIs. Figure (<b>b</b>) is the spatial distribution diagram with nodes in the ferrying lanes and different POI categories. The used map is extracted from the Chinese BaiDu Map. All the information in the map is shown by Chinese words. The blue POIs are included in the category “Catering and Shopping”, the red POIs are included in the category “Museum and Historical site”, the green POIs are included in the category “Natural scenery and Park”. The yellow dots represent the starting point and terminal point of the ICV lane. The blue dots and red dot represent the critical nodes of the ICV lane.</p>
Full article ">Figure 9
<p>The clustering objective function value between the seed points and the POIs. Figure (<b>a</b>) shows the <math display="inline"><semantics> <mrow> <mrow> <mi>f</mi> <mo stretchy="false">(</mo> <mi>P</mi> <mo stretchy="false">(</mo> <mi>x</mi> <mo stretchy="false">)</mo> <mo>,</mo> <mi>P</mi> <mo stretchy="false">(</mo> <mi>y</mi> <mo stretchy="false">)</mo> <mo stretchy="false">)</mo> </mrow> </mrow> </semantics></math> values between the seed point <math display="inline"><semantics> <mrow> <mrow> <mi>P</mi> <mo stretchy="false">(</mo> <mn>1</mn> <mo stretchy="false">)</mo> </mrow> </mrow> </semantics></math>: The Jinsha Site and other POIs. Figure (<b>b</b>) shows the <math display="inline"><semantics> <mrow> <mrow> <mi>f</mi> <mo stretchy="false">(</mo> <mi>P</mi> <mo stretchy="false">(</mo> <mi>x</mi> <mo stretchy="false">)</mo> <mo>,</mo> <mi>P</mi> <mo stretchy="false">(</mo> <mi>y</mi> <mo stretchy="false">)</mo> <mo stretchy="false">)</mo> </mrow> </mrow> </semantics></math> values between the seed point <math display="inline"><semantics> <mrow> <mrow> <mi>P</mi> <mo stretchy="false">(</mo> <mn>6</mn> <mo stretchy="false">)</mo> </mrow> </mrow> </semantics></math>: The Tazishan Park and other POIs. Figure (<b>c</b>) shows the <math display="inline"><semantics> <mrow> <mrow> <mi>f</mi> <mo stretchy="false">(</mo> <mi>P</mi> <mo stretchy="false">(</mo> <mi>x</mi> <mo stretchy="false">)</mo> <mo>,</mo> <mi>P</mi> <mo stretchy="false">(</mo> <mi>y</mi> <mo stretchy="false">)</mo> <mo stretchy="false">)</mo> </mrow> </mrow> </semantics></math> values between the seed point <math display="inline"><semantics> <mrow> <mrow> <mi>P</mi> <mo stretchy="false">(</mo> <mn>11</mn> <mo stretchy="false">)</mo> </mrow> </mrow> </semantics></math>: The Jinniu Wanda and other POIs.</p>
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<p>ICV ferrying lane and POI distributions, POI interest matching objective function value distributions and the optimal POI selected at time <math display="inline"><semantics> <mrow> <mrow> <msub> <mi>t</mi> <mi>a</mi> </msub> </mrow> </mrow> </semantics></math> and its relative location point. Figure (<b>a</b>,<b>b</b>) show the distribution of the ICV lane, POIs and nodes of the ICV lane. The used map is extracted from the Chinese BaiDu Map. All the information in the map is shown by Chinese words. In Figure (<b>a</b>,<b>b</b>), the blue POIs are included in the category “Catering and Shopping”, the red POIs are included in the category “Museum and Historical site”, the green POIs are included in the category “Natural scenery and Park”. The yellow dots represent the starting point and terminal point of the ICV lane. The red dots represent the critical nodes of the ICV lane. Figure (<b>c</b>) shows that the POI <math display="inline"><semantics> <mrow> <mrow> <mi>P</mi> <mo stretchy="false">(</mo> <mn>2</mn> <mo stretchy="false">)</mo> </mrow> </mrow> </semantics></math> is found and confirmed. Figure (<b>d</b>) shows that the POI <math display="inline"><semantics> <mrow> <mrow> <mi>P</mi> <mo stretchy="false">(</mo> <mn>3</mn> <mo stretchy="false">)</mo> </mrow> </mrow> </semantics></math> is found and confirmed. Figure (<b>e</b>) shows that the POI <math display="inline"><semantics> <mrow> <mrow> <mi>P</mi> <mo stretchy="false">(</mo> <mn>5</mn> <mo stretchy="false">)</mo> </mrow> </mrow> </semantics></math> is found and confirmed. Figure (<b>f</b>) shows that the POI <math display="inline"><semantics> <mrow> <mrow> <mi>P</mi> <mo stretchy="false">(</mo> <mn>10</mn> <mo stretchy="false">)</mo> </mrow> </mrow> </semantics></math> is found and confirmed. The blue dots are the nodes that have been passed by the ICV.</p>
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<p>The experimental results under the same experimental conditions as Long [<a href="#B28-symmetry-16-01431" class="html-bibr">28</a>]. Figure (<b>a</b>) shows the spatial scenario under the simple conditions; Figure (<b>b</b>) shows the ICV route output by the proposed algorithm under the simple conditions; Figure (<b>c</b>) shows the spatial scenario under the complex conditions, and Figure (<b>d</b>) shows the ICV route output by the proposed algorithm under the complex conditions. The routes are drawn by red dashed lines. In the figures, the black areas represent the obstacles in the space.</p>
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<p>Result comparison between <b>exp.</b> and <b>c.</b> Figure (<b>a</b>) shows the POI matching function values and the “<math display="inline"><semantics> <mrow> <mrow> <mi>Tot</mi> <mo>.</mo> </mrow> </mrow> </semantics></math>” values of <b>exp.</b> Figure (<b>b</b>–<b>d</b>) show the POI matching function values and the “<math display="inline"><semantics> <mrow> <mrow> <mi>Tot</mi> <mo>.</mo> </mrow> </mrow> </semantics></math>” values for <b>c1.</b>, <b>c2.</b> and <b>c3.</b> The red square is marked as “<math display="inline"><semantics> <mrow> <mrow> <mi>Tot</mi> <mo>.</mo> </mrow> </mrow> </semantics></math>” value. Figure (<b>e</b>) shows the POI matching function values and “<math display="inline"><semantics> <mrow> <mrow> <mi>Aver</mi> <mo>.</mo> </mrow> </mrow> </semantics></math>” values in <b>exp.</b> Figures (<b>f</b>–<b>h</b>) show the POI matching function values and “<math display="inline"><semantics> <mrow> <mrow> <mi>Aver</mi> <mo>.</mo> </mrow> </mrow> </semantics></math>” values in <b>c1.</b>, <b>c2.</b> and <b>c3.</b> The green square is marked as“<math display="inline"><semantics> <mrow> <mrow> <mi>Aver</mi> <mo>.</mo> </mrow> </mrow> </semantics></math>”value. Figure (<b>i</b>) shows the “<math display="inline"><semantics> <mrow> <mrow> <mo>Δ</mo> <mi>Tot</mi> <mo>.</mo> </mrow> </mrow> </semantics></math>” between the different groups. Figure (<b>j</b>) shows the “<math display="inline"><semantics> <mrow> <mrow> <mo>Δ</mo> <mi>Aver</mi> <mo>.</mo> </mrow> </mrow> </semantics></math>” between different groups. Figure (<b>k</b>) shows the “<math display="inline"><semantics> <mrow> <mrow> <mi>Var</mi> <mo>.</mo> </mrow> </mrow> </semantics></math>” value in each group and Figure (<b>l</b>) shows the “<math display="inline"><semantics> <mrow> <mrow> <mi>Std</mi> <mo>.</mo> </mrow> </mrow> </semantics></math>” value in each group.</p>
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<p>The comparison of the “<math display="inline"><semantics> <mrow> <mrow> <mi>Tot</mi> <mo>.</mo> </mrow> </mrow> </semantics></math>” and “<math display="inline"><semantics> <mrow> <mrow> <mi>Dis</mi> <mo>.</mo> </mrow> </mrow> </semantics></math>” tour routes in each group. Figure (<b>a</b>) shows the curve of “<math display="inline"><semantics> <mrow> <mrow> <mi>Tot</mi> <mo>.</mo> </mrow> </mrow> </semantics></math>” for the tour routes of each group, Figure (<b>b</b>) shows the curve of “<math display="inline"><semantics> <mrow> <mrow> <mi>Dis</mi> <mo>.</mo> </mrow> </mrow> </semantics></math>” for the tour routes of each group, Figure (<b>c</b>) shows the curve of “<math display="inline"><semantics> <mrow> <mrow> <mo>Δ</mo> <mi>Tot</mi> <mo>.</mo> </mrow> </mrow> </semantics></math>” of the tour between <b>exp.</b> and <b>c1~4.</b> and Figure (<b>d</b>) shows the curve of “<math display="inline"><semantics> <mrow> <mrow> <mo>Δ</mo> <mi>Dis</mi> <mo>.</mo> </mrow> </mrow> </semantics></math>” of the tour between <b>exp.</b> and <b>c1~4.</b></p>
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20 pages, 2643 KiB  
Article
A Tour Recommendation System Considering Implicit and Dynamic Information
by Chieh-Yuan Tsai, Kai-Wen Chuang, Hen-Yi Jen and Hao Huang
Appl. Sci. 2024, 14(20), 9271; https://doi.org/10.3390/app14209271 - 11 Oct 2024
Viewed by 1027
Abstract
Tourism has become one of the world’s largest service industries. Due to the rapid development of social media, more people like self-guided tours than package itineraries planned by travel agencies. Therefore, how to develop itinerary recommendation systems that can provide practical tour suggestions [...] Read more.
Tourism has become one of the world’s largest service industries. Due to the rapid development of social media, more people like self-guided tours than package itineraries planned by travel agencies. Therefore, how to develop itinerary recommendation systems that can provide practical tour suggestions for tourists has become an important research topic. This study proposes a novel tour recommendation system that considers the implicit and dynamic information of Point-of-Interest (POI). Our approach is based on users’ photo information uploaded to social media in various tourist attractions. For each check-in record, we will find the POI closest to the user’s check-in Global Positioning System (GPS) location and consider the POI as the one they want to visit. Instead of using explicit information such as categories to represent POIs, this research uses the implicit feature extracted from the textual descriptions of POIs. Textual description for a POI contains rich and potential information describing the POI’s type, facilities, or activities, which makes it more suitable to represent a POI. In addition, this study considers visiting sequences when evaluating user similarity during clustering so that tourists in each sub-group hold higher behavior similarity. Next, the Non-negative Matrix Factorization (NMF) dynamically derives the staying time for different users, time slots, and POIs. Finally, a personalized itinerary algorithm is developed that considers user preference and dynamic staying time. The system will recommend the itinerary with the highest score and the longest remaining time. A set of experiments indicates that the proposed recommendation system outperforms state-of-the-art next POI recommendation methods regarding four commonly used evaluation metrics. Full article
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<p>The framework of the proposed tour recommendation system.</p>
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<p>The network structure of AE.</p>
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<p>The distribution of user check-in points in the Tokyo area.</p>
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<p>The distribution of length of visiting sequences.</p>
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<p>The silhouette coefficients under different k values.</p>
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<p>(<b>a</b>) The average number of POIs suggested by each method. (<b>b</b>) The average reaming time (in hours) left by each method.</p>
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<p>(<b>a</b>) The performance metrics of MAP@5 and P@5 (<b>b</b>) the performance metrics of NDCG@5 and MRR@5 when the number of clusters is from 2 to 6.</p>
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<p>The MRR@5 of the proposed recommendation system when different weight settings of user preference are applied.</p>
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<p>The average number of recommended POIs for each cluster.</p>
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<p>The average itinerary score for each cluster.</p>
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15 pages, 2032 KiB  
Article
Accuracy of Infrared Thermography in Diagnosing Breast Cancer-Related Lymphedema
by Vanessa Maria da Silva Alves Gomes, Marcos Leal Brioschi, Ana Rafaela Cardozo da Silva, Naiany Tenório, Laura Raynelle Patriota Oliveira, Ana Claúdia Souza da Silva, Juliana Netto Maia and Diego Dantas
J. Clin. Med. 2024, 13(20), 6054; https://doi.org/10.3390/jcm13206054 - 11 Oct 2024
Viewed by 1005
Abstract
Background/Objectives: Infrared thermography (IRT) is an imaging technique used in clinical practice to detect changes in skin temperature caused by several dysfunctions, including breast cancer-related lymphedema (BCRL). Thus, the present study aimed to assess the reproducibility and accuracy of IRT in diagnosing BCRL. [...] Read more.
Background/Objectives: Infrared thermography (IRT) is an imaging technique used in clinical practice to detect changes in skin temperature caused by several dysfunctions, including breast cancer-related lymphedema (BCRL). Thus, the present study aimed to assess the reproducibility and accuracy of IRT in diagnosing BCRL. Methods: This cross-sectional study included participants who underwent a unilateral mastectomy and used indirect volumetry for lymphedema detection. IRT analysis was recorded in four positions, analyzing maximum, mean, and minimum temperatures, as well as the temperature differences between the upper limbs. The analysis encompassed reliability, agreement, accuracy, and the establishment of cut-off points for sensitivity and specificity. A total of 88 upper limbs were included; 176 thermograms were captured, and 1056 regions of interest were analyzed. Results: IRT presented excellent intra- and inter-rater reproducibility and reliability with excellent intraclass correlation coefficient values (0.99 to 1.00). In addition, this assessment reached a sensitivity of 85% and a specificity of 56%; the cut-off point considered a temperature difference of −0.45 °C. Conclusions: IRT was a reliable and reproducible assessment, and the temperature difference between the upper limbs evidenced moderate accuracy. Thus, IRT is recommended as a complementary technique for detecting BCRL. Full article
(This article belongs to the Section Vascular Medicine)
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<p>Representation of the region of interest in different positions for infrared thermography in the diagnosis of breast cancer-related lymphedema. Subfigures show the positions for capturing the infrared thermography images: (<b>A</b>) anterior anatomical position (frontal area of upper limbs); (<b>B</b>) posterior anatomical position (posterior area of upper limbs); (<b>C</b>) anterior position with arms abduction (anterior lateral region); and (<b>D</b>) posterior position with arms abduction (posterior lateral region).</p>
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<p>Flowchart of the screening and data collection process. This flowchart outlines participant selection, delineates inclusion and exclusion criteria, and classifies the participants as upper limbs with lymphedema (ULWL) or upper limbs control (ULC).</p>
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<p>Receiver-operating characteristic curves compare skin temperatures in upper limbs (maximum, mean, and minimum), differentiating between upper limbs with lymphedema and those without lymphedema in all positions.</p>
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<p>Receiver-operating characteristic curves of maximum, mean, and minimum skin temperatures for delta values in each position.</p>
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22 pages, 6791 KiB  
Article
Potential Role of Tarantula Venom Peptides in Targeting Human Death Receptors: A Computational Study
by Janus Isaiah R. Quiambao, Peter Matthew Paul T. Fowler and Lemmuel L. Tayo
Appl. Sci. 2024, 14(19), 8701; https://doi.org/10.3390/app14198701 - 26 Sep 2024
Viewed by 1403
Abstract
Animal venom has been gaining traction as a potential source of therapeutics for various diseases. Spiders encompass a wide variety of venom-producing species, of which tarantulas of the family Theraphosidae are widely known across the globe. Research towards tarantula venom therapeutics has led [...] Read more.
Animal venom has been gaining traction as a potential source of therapeutics for various diseases. Spiders encompass a wide variety of venom-producing species, of which tarantulas of the family Theraphosidae are widely known across the globe. Research towards tarantula venom therapeutics has led to its potential application as antinociceptives. Death receptors are cellular receptors that induce apoptosis—the body’s natural suicide mechanism—to destroy malfunctioning cells. These are particularly of interest in cancer research, as this mechanism is tampered with, resulting in cancer cell proliferation. In this study, the viability of venom toxins from the Theraphosidae family of spiders to induce apoptosis by binding to human death receptors is investigated by carrying out anti-cancer screening, molecular docking, ADMET evaluation, then molecular dynamics and thermodynamic analysis twice, first to ascertain the best receptor–peptide systems per receptor, and secondly to more comprehensively describe binding stability and thermodynamics. Results point to favorable receptor–peptide interactions due to similarities in equilibrium behavior with the death ligand–death receptor systems, along with favorable end-state binding energies and ADMET analysis results. Further inquiry is recommended to assess the real-life efficacy and viability of theraphotoxins as apoptosis therapeutics and further improve on their ability to induce apoptosis. Full article
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<p>Expression of death receptors in different cancer types. Data obtained from the Human Protein Atlas. NPX—Normalized Protein eXpression.</p>
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<p>Methodological flow chart.</p>
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<p>Multiple sequence alignments and similarity scores of the top 20 anti-cancer peptides. (*) indicate that a residue is similar to all peptides. (**) are just two different amino acids that are similar in all sequences tested.</p>
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<p>Violin plots of anti-cancer scores and physicochemical properties.</p>
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<p>Plots for the HADDOCK scores and Z-scores from the molecular docking of the top 10 peptides.</p>
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<p>Docked death receptor and ligand systems. Green, blue, and pink represent chains A, B, and C of the receptor, while yellow represents the ligand. The letter of each docked system correspond to the identity of the peptide that was docked.</p>
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<p>Docked death receptor and ligand systems. Green, blue, and pink represent chains A, B, and C of the receptor, while yellow represents the ligand. The letter of each docked system correspond to the identity of the peptide that was docked.</p>
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<p>100 ns molecular dynamics results for the death receptor 4 and Q system.</p>
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<p>100 ns molecular dynamics results for the death receptor 5 and Q system.</p>
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<p>100 ns molecular dynamics results for the TNFR-1 and A system.</p>
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<p>100 ns molecular dynamics results for the Fas and I system.</p>
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<p>End-state thermodynamics results of the four systems.</p>
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<p>Radar plots of the ADMET characteristics of simulated theraphotoxins. Numerical values in Cytochrome P450 plots correspond to their probability as substrates.</p>
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<p>Radar plots of the ADMET characteristics of simulated theraphotoxins. Numerical values in Cytochrome P450 plots correspond to their probability as substrates.</p>
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20 pages, 5498 KiB  
Article
Numerical Analysis of a Self-Acting Gas Bearing Lubricated with a Low-Boiling-Point Medium Using an Advanced Model Based on the Finite Difference Methods and Universal Computational Fluid Dynamics Software
by Małgorzata Bogulicz, Paweł Bagiński and Grzegorz Żywica
Appl. Sci. 2024, 14(17), 7520; https://doi.org/10.3390/app14177520 - 26 Aug 2024
Viewed by 953
Abstract
Methods for determining the characteristics of self-acting (aerodynamic) gas bearings have been developed for many years, but many researchers and engineers still question how sophisticated a model of such bearings should be to obtain reliable results. This is the subject of this article, [...] Read more.
Methods for determining the characteristics of self-acting (aerodynamic) gas bearings have been developed for many years, but many researchers and engineers still question how sophisticated a model of such bearings should be to obtain reliable results. This is the subject of this article, which presents a numerical analysis of aerodynamic gas bearings using two alternative methods: a specialized program based on the finite difference method, and a universal CFD program using the finite volume method. Gas bearings with a nominal diameter of 49 mm, designed for a 10 kW turbogenerator operating at a rotational speed of 40,000 rpm, are analyzed. The vapor of the low-boiling medium, designated HFE-7100, is used as the bearing lubricant. The calculations focus on determining the position of the bearing journal where the bearing achieved the required load capacity and checking the bearing characteristics beyond the nominal operating point. The most important results obtained by the two independent methods are compared, and recommendations are made for those interested in the numerical analysis of self-acting gas bearings. Full article
(This article belongs to the Special Issue Rotor Dynamics: Research and Applications)
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<p>(<b>a</b>) Geometrical dimensions of the analyzed hybrid bearing supplied obliquely. (<b>b</b>) Coordinate system describing the position of the journal in the bearing.</p>
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<p>Load capacity and journal center position angle vs. dimensionless eccentricity in a gas-dynamic bearing—calculation results from the GAZBEAR program.</p>
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<p>Distribution of gas film thickness in the bearing lubrication gap, with the journal center positioned at a point with a relative eccentricity of 0.16 at an angle of 336°.</p>
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<p>Pressure distribution in the bearing lubrication gap, with the journal center positioned at a point with a relative eccentricity of 0.16 at an angle of 336°.</p>
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<p>Discretized lubrication space domain of a gas bearing.</p>
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<p>Boundary conditions of the flow model for the dynamic bearing with a marked local coordinate system.</p>
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<p>Load capacity maps of the gas-dynamic bearing for given input parameters: (<b>a</b>) in the Y direction; (<b>b</b>) in the X direction.</p>
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<p>Changes in the reaction force of the lubrication film in the gas-dynamic bearing: (<b>a</b>) in the Y direction for selected eccentricities vs. journal position angle; (<b>b</b>) in the Y direction for selected angles vs. relative eccentricity; (<b>c</b>) in the X direction for selected eccentricities vs. journal position angle; (<b>d</b>) in the X direction for selected angles vs. relative eccentricity.</p>
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<p>Pressure distribution in a gas-dynamic bearing: (<b>a</b>) on the journal surface; (<b>b</b>) in the plane of symmetry, in the plane corresponding to ¼ of the bearing length, and on the bearing edge (outlet plane).</p>
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<p>Gas flow in a gas-dynamic bearing: (<b>a</b>) streamlines; (<b>b</b>) vectors indicating the flow directions.</p>
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<p>Aerodynamic lift of the gas-dynamic bearing vs. relative eccentricity, determined using the GAZBEAR and ANSYS CFX programs.</p>
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<p>Pressure distribution on the sleeve surface in a gas-dynamic bearing for a static equilibrium point at a speed of 40,000 rpm: (<b>a</b>) results from the GAZBEAR program; (<b>b</b>) results from the ANSYS CFX software.</p>
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<p>Static equilibrium semicircles of the gas-dynamic bearing calculated using the GAZBEAR and ANSYS CFX programs.</p>
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14 pages, 577 KiB  
Article
Extracting Representations from Multi-View Contextual Graphs via Convolutional Neural Networks for Point-of-Interest Recommendation
by Shaojie Jiang, Wen Feng and Xuefeng Ding
Appl. Sci. 2024, 14(16), 7010; https://doi.org/10.3390/app14167010 - 9 Aug 2024
Cited by 1 | Viewed by 963
Abstract
In recent years, graph-based learning methods have gained significant traction in point-of-interest (POI) recommendation systems due to their strong generalization capabilities. These approaches commonly transform user check-in records into graph-structured data and leverage graph neural networks (GNNs) to model the representations of both [...] Read more.
In recent years, graph-based learning methods have gained significant traction in point-of-interest (POI) recommendation systems due to their strong generalization capabilities. These approaches commonly transform user check-in records into graph-structured data and leverage graph neural networks (GNNs) to model the representations of both POIs and users. Despite their effectiveness, GNNs face inherent limitations in message passing, which can impede the deep extraction of meaningful representations from the graph structure. To mitigate this challenge, we introduce a novel framework, Multi-view Contextual Graphs via Convolutional Neural Networks for Point-of-Interest Recommendation (MCGRec). The MCGRec framework consists of three primary components. Firstly, it employs a personalized PageRank (PPR) sampling technique based on super nodes to transform the graph-structured data into a grid-like feature matrix. This step is crucial as it prepares the data for subsequent processing by convolutional neural networks (CNNs), which are adept at extracting spatial features from grid-like structures. Secondly, a CNN is utilized to extract the representations of POIs from the constructed feature matrix. The usage of CNNs enables the capture of local patterns and hierarchical features within the data, which are essential for accurate POI representation. Lastly, MCGRec incorporates a novel approach for estimating user preferences that integrates both geographical and temporal factors, thereby providing a more comprehensive model of users’ behaviors. To evaluate the effectiveness of our proposed method, we conduct extensive experiments on real-world datasets. Our results demonstrate that MCGRec outperforms state-of-the-art POI recommendation methods, showcasing its superiority in terms of recommendation accuracy. Full article
(This article belongs to the Special Issue Recommender Systems and Their Advanced Application)
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<p>The overall framework of MCGRec.</p>
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<p>Performance of MCGRec with different <span class="html-italic">β</span> on NYC in terms of Precision.</p>
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<p>Performance of MCGRec with different <span class="html-italic">β</span> on NYC in terms of Recall.</p>
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23 pages, 4662 KiB  
Review
Decoding the Developmental Trajectory of Energy Trading in Power Markets through Bibliometric and Visual Analytics
by Yu Sun, Zhiqiang Ma, Xiaomeng Chi, Jiaqi Duan, Mingxing Li and Asad Ullah Khan
Energies 2024, 17(15), 3605; https://doi.org/10.3390/en17153605 - 23 Jul 2024
Cited by 1 | Viewed by 862
Abstract
This research leverages bibliometric methodologies, enhanced by the visual analytics capabilities of CiteSpace, to meticulously examine the evolution and current trends in energy trading within power markets, analyzing 642 scholarly articles from the Web of Science Core Collection spanning from 1996 to 2023. [...] Read more.
This research leverages bibliometric methodologies, enhanced by the visual analytics capabilities of CiteSpace, to meticulously examine the evolution and current trends in energy trading within power markets, analyzing 642 scholarly articles from the Web of Science Core Collection spanning from 1996 to 2023. The study aims to illuminate the prevailing research landscape, growth patterns, and future directions in energy trading dynamics. Key findings include: (1) A noticeable escalation in the volume of publications, especially from 2021 to 2023, indicating a burgeoning interest and rapid evolution in this research area; (2) The author and institutional collaboration networks are in a nascent stage, with a predominantly China-centric international collaboration pattern, including significant partnerships with the United States, Australia, and the United Kingdom; (3) The focal points of research are centered around themes such as “energy management”, “demand-side innovation”, “decentralized energy trading”, and “strategic optimization”, covering areas such as intelligent grid technologies, energy market dynamics, and sustainable energy solutions. The study recommends enhancing collaborative networks, fusing technological and strategic dimensions in research, increasing focus and funding for emerging technologies, and promoting wider international and cross-disciplinary collaborations to enrich the understanding of energy trading dynamics in the context of electricity markets. Full article
(This article belongs to the Section C: Energy Economics and Policy)
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<p>Flowchart of the Research Methodology.</p>
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<p>The number of published papers from 2001 to 2022.</p>
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<p>CiteSpace-based mapping of national (regional) cooperation.</p>
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<p>CiteSpace-based author collaboration mapping.</p>
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<p>CiteSpace-based organizational collaboration mapping.</p>
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<p>CiteSpace-based co-citation mapping of journals.</p>
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<p>CiteSpace-based keyword co-linearity mapping.</p>
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<p>CiteSpace based keyword clustering mapping.</p>
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<p>CiteSpace-based timeline mapping.</p>
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