Search Results (67)

The rapid development of blockchain has significantly promoted research on zero-knowledge proofs (ZKPs), especially zero-knowledge succinct noninteractive arguments of knowledge (zk-SNARK). As is well known, protocol proof and verification time, as well as proof size, are the main obstacles that restrict the implementation of ZKPs in practical applications, so they have become the main concerns of researchers in recent years. This work achieves a new recursive zk-SNARK called GENES, which does not have a trusted setup and is secure under the standard discrete logarithm assumption. GENES is designed from the form of the rank-1 constraint system (R1CS) satisfiability problem. Recursive proof composition is achieved by merging multiple R1CS instances, which transforms the verification of numerous proofs into the verification of a single proof. Moreover, multi-helpers amortize proof commitments in this study, significantly reducing the computational pressure and time cost of proof generation. Compared with previous work, GENES effectively improves the proof time and verification time, but at the cost of larger proof sizes. We provide a blockchain Layer-1 scaling solution leveraging GENES to demonstrate its practicality. Full article

Background: Burns and chronic ulcers may cause severe skin loss, leading to critical health issues like shock, infection, sepsis, and multiple organ failure. Effective healing of full-thickness wounds may be challenging, with traditional methods facing limitations due to tissue shortage, infection, and lack of structural support. Methods: This study explored the combined use of gene transfection and dermal substitutes to improve wound healing. We used the DGTM (genes: DNP63A, GRHL2, TFAP2A, and MYC) factors to transfect adipose-derived stem cells (ADSCs), inducing their differentiation into keratinocytes. These transfected ADSCs were then incorporated into Pelnac^® dermal substitutes to enhance vascularization and cellular proliferation for better healing outcomes. Results: Gene transfer using DGTM factors successfully induced keratinocyte differentiation in ADSCs. The application of these differentiated cells with Pelnac^® dermal substitute to dermal wounds in mice resulted in the formation of skin tissue with a normal epidermal layer and proper collagen organization. This method alleviates the tediousness of the multiple transfection steps in previous protocols and the safety issues caused by using viral transfection reagents directly on the wound. Additionally, the inclusion of dermal substitutes addressed the lack of collagen and elastic fibers, promoting the formation of tissue resembling healthy skin rather than scar tissue. Conclusion: Integrating DGTM factor-transfected ADSCs with dermal substitutes represents a novel strategy for enhancing the healing of full-thickness wounds. Further research and clinical trials are warranted to optimize and validate this innovative approach for broader clinical applications. Full article

In this paper, we introduce the Secured Real-Time Machine Communication Protocol (SRMCP), a novel industrial communication protocol designed to address the increasing demand for security and performance in Industry 4.0 environments. SRMCP integrates post-quantum cryptographic techniques, including the Kyber Key Encapsulation Mechanism (Kyber-KEM) and AES-GCM encryption, to ensure robust protection against both current and future cryptographic threats. We also present an innovative “Port Hopping” mechanism inspired by frequency hopping, enhancing security by distributing communication across multiple channels. Comparative performance analysis was conducted with widely-used protocols such as ModBus and the OPC UA, focusing on key metrics such as connection, reading, and writing times across local and remote networks. Results demonstrate that SRMCP outperforms ModBus in reading and writing operations while offering enhanced security, although it has a higher connection time due to its dual-layer encryption. The OPC UA, while secure, lags significantly in performance, making it less suitable for real-time applications. The findings suggest that SRMCP is a viable solution for secure and efficient machine communication in modern industrial settings, particularly where quantum-safe security is a concern. Full article

Power management (PM) is cumbersome for today’s computing systems. Attainable performance is bounded by the architecture’s computing efficiency and capped in temperature, current, and power. PM is composed of multiple interacting layers. High-level controllers (HLCs) involve application-level policies, operating system agents (OSPMs), and PM governors and interfaces. The application of high-level control decisions is currently delegated to an on-chip power management unit executing tailored PM firmware routines. The complexity of this structure arises from the scale of the interaction, which pervades the whole system architecture. This paper aims to characterize the cost of the communication backbone between high-level OSPM agents and the on-chip power management unit (PMU) in high performance computing (HPC) processors. For this purpose, we target the System Control and Management Interface (SCMI), which is an open standard proposed by Arm. We enhance a fully open-source, end-to-end FPGA-based HW/SW framework to simulate the interaction between a HLC, a HPC system, and a PMU. This includes the application-level PM policies, the drivers of the operating system-directed configuration and power management (OSPM) governor, and the hardware and firmware of the PMU, allowing us to evaluate the impact of the communication backbone on the overall control scheme. With this framework, we first conduct an in-depth latency study of the communication interface across the whole PM hardware (HW) and software (SW) stack. Finally, we studied the impact of latency in terms of the quality of the end-to-end control, showing that the SCMI protocol can sustain reactive power management policies. Full article

In modern Internet-based communication, especially mobile systems, a mobile node (MN) will commonly have more than one possibility for Internet Protocol (IP) connectivity. For example, an MN such as a smartphone may be associated with an IEEE 802.11 network at a site while also connected to a cellular base station for 5G. In such a scenario, the smartphone might only be able to utilise the IEEE 802.11 network, not making use of the cellular connectivity simultaneously. Currently, IP does not allow applications and devices to easily utilise multiple IP connectivity opportunities—multihoming for the MN—without implementing special mechanisms to manage them. We demonstrate how the use of the Identifier Locator Network Protocol (ILNP), realised as an extension to IPv6, can enable mobility with multihoming using a duality mechanism that treats mobility and multihoming as the same logical concept. We present a network layer solution that does not require any modification to transport protocols, can be implemented using existing application programming interfaces (APIs), and can work for any application. We have evaluated our approach using an implementation in Linux and a testbed. The testbed consisted of commercial equipment to demonstrate that our approach can be used over existing network infrastructure requiring only normal unicast routing for IPv6. Full article

The Internet of Things (IoT) has recently received a great deal of research interest due to its broad range of applications. One of the important layers in IoT applications is known as edge computing where resource-constrained devices at the edge form a simple type of network to sense required data. A more powerful edge device is responsible for collecting all sensed data to be transferred to the upper layers. A critical focus is therefore placed on maximum rate of data collection, requiring effective and intelligent solutions to coordinate the channel access of the devices. Medium access control (MAC) protocols take this responsibility as their design mission. Carrier-sense multiple access (CSMA) has been a baseline MAC scheme and many previous traditional networks utilized a CSMA-based solution. The motivation of this paper is to study the performance of a typical network at the edge through the CSMA theme. A practical network is constructed to assess the channel throughput performance via a commercially available radio transceiver. The practical performance observations indicate the suitability of the proposed CSMA-based solution. Full article

The rapid advancement of technology, alongside state-of-the-art techniques is at an all-time high. However, this unprecedented growth of technological prowess also brings forth potential threats, as oftentimes the security encompassing these technologies is imperfect. Particularly within the automobile industry, the recent strides in technology have brought about increased complexity. A notable flaw lies in the CAN-FD protocol, which lacks robust security measures, making it vulnerable to data theft, injection, replay, and flood data attacks. With the rising complexity of in-vehicular networks and the widespread adoption of CAN-FD, the imperative to safeguard the protocol has never been more crucial. This paper aims to provide a comprehensive review of the existing in-vehicle communication protocol, CAN-FD. It explores existing security approaches designed to fortify CAN-FD, demonstrating multiple multi-layer solutions that leverage modern techniques including Physical Unclonable Function (PUF), Elliptical Curve Cryptography (ECC), Ethereum Blockchain, and Smart contracts. The paper highlights existing multi-layer security measures that offer minimal overhead, optimal performance, and robust security. Moreover, it identifies areas where these security measures fall short and discusses ongoing research along with suggestions for implementing software and hardware-level modifications. These proposed changes aim to streamline complexity, reduce overhead while ensuring forward compatibility. In essence, the methods outlined in this study are poised to excel in real-world applications, offering robust protection for the evolving landscape of in-vehicular communication systems. Full article

Opportunistic networks, an evolution of mobile Ad Hoc networks (MANETs), offer decentralized communication without relying on preinstalled infrastructure, enabling nodes to route packets through different mobile nodes dynamically. However, due to the absence of complete paths and rapidly changing connectivity, routing in opportunistic networks presents unique challenges. This paper proposes a novel probabilistic routing model for opportunistic networks, leveraging nodes’ meeting probabilities to route packets towards their destinations. Thismodel dynamically builds routes based on the likelihood of encountering the destination node, considering factors such as the last meeting time and acknowledgment tables to manage network overload. Additionally, an efficient message detection scheme is introduced to alleviate high overhead by selectively deleting messages from buffers during congestion. Furthermore, the proposed model incorporates cross-layer optimization techniques, integrating optimization strategies across multiple protocol layers to maximize energy efficiency, adaptability, and message delivery reliability. Through extensive simulations, the effectiveness of the proposed model is demonstrated, showing improved message delivery probability while maintaining reasonable overhead and latency. This research contributes to the advancement of opportunistic networks, particularly in enhancing connectivity and efficiency for Internet of Things (IoT) applications deployed in challenging environments. Full article

The damping system ensured by the osteochondral (OC) unit is essential to deploy the forces generated within load-bearing joints during locomotion, allowing furthermore low-friction sliding motion between bone segments. The OC unit is a multi-layer structure including articular cartilage, as well as subchondral and trabecular bone. The interplay between the OC tissues is essential in maintaining the joint functionality; altered loading patterns can trigger biological processes that could lead to degenerative joint diseases like osteoarthritis. Currently, no effective treatments are available to avoid degeneration beyond tissues’ recovery capabilities. A thorough comprehension on the mechanical behaviour of the OC unit is essential to (i) soundly elucidate its overall response to intra-articular loads for developing diagnostic tools capable of detecting non-physiological strain levels, (ii) properly evaluate the efficacy of innovative treatments in restoring physiological strain levels, and (iii) optimize regenerative medicine approaches as potential and less-invasive alternatives to arthroplasty when irreversible damage has occurred. Therefore, the leading aim of this review was to provide an overview of the state-of-the-art—up to 2022—about the mechanical behaviour of the OC unit. A systematic search is performed, according to PRISMA standards, by focusing on studies that experimentally assess the human lower-limb joints’ OC tissues. A multi-criteria decision-making method is proposed to quantitatively evaluate eligible studies, in order to highlight only the insights retrieved through sound and robust approaches. This review revealed that studies on human lower limbs are focusing on the knee and articular cartilage, while hip and trabecular bone studies are declining, and the ankle and subchondral bone are poorly investigated. Compression and indentation are the most common experimental techniques studying the mechanical behaviour of the OC tissues, with indentation also being able to provide information at the micro- and nanoscales. While a certain comparability among studies was highlighted, none of the identified testing protocols are currently recognised as standard for any of the OC tissues. The fibril-network-reinforced poro-viscoelastic constitutive model has become common for describing the response of the articular cartilage, while the models describing the mechanical behaviour of mineralised tissues are usually simpler (i.e., linear elastic, elasto-plastic). Most advanced studies have tested and modelled multiple tissues of the same OC unit but have done so individually rather than through integrated approaches. Therefore, efforts should be made in simultaneously evaluating the comprehensive response of the OC unit to intra-articular loads and the interplay between the OC tissues. In this regard, a multidisciplinary approach combining complementary techniques, e.g., full-field imaging, mechanical testing, and computational approaches, should be implemented and validated. Furthermore, the next challenge entails transferring this assessment to a non-invasive approach, allowing its application in vivo, in order to increase its diagnostic and prognostic potential. Full article

The OSI model used to be a common network model for years. In the case of ad hoc networks with dynamic topology and difficult radio communications conditions, gradual departure is happening from the classical kind of OSI network model with a clear delineation of layers (physical, channel, network, transport, application) to the cross-layer approach. The layers of the network model in ad hoc networks strongly influence each other. Thus, the cross-layer approach can improve the performance of an ad hoc network by jointly developing protocols using interaction and collaborative optimization of multiple layers. The existing cross-layer methods classification is too complicated because it is based on the whole manifold of network model layer combinations, regardless of their importance. In this work, we review ad hoc network cross-layer methods, propose a new useful classification of cross-layer methods, and show future research directions in the development of ad hoc network cross-layer methods. The proposed classification can help to simplify the goal-oriented cross-layer protocol development. Full article

The Internet of vehicles (IoV) is an Internet-of-things-based network in the area of transportation. It comprises sensors, network communication, automation control, and data processing and enables connectivity between vehicles and other objects. This study performed main path analysis (MPA) to investigate the trajectory of research regarding the IoV. Studies were extracted from the Web of Science database, and citation networks among these studies were generated. MPA revealed that research in this field has mainly covered media access control, vehicle-to-vehicle channels, device-to-device communications, layers, non-orthogonal multiple access, and sixth-generation communications. Cluster analysis and data mining revealed that the main research topics related to the IoV included wireless channels, communication protocols, vehicular ad hoc networks, security and privacy, resource allocation and optimization, autonomous cruise control, deep learning, and edge computing. By using data mining and statistical analysis, we identified emerging research topics related to the IoV, namely blockchains, deep learning, edge computing, cloud computing, vehicular dynamics, and fifth- and sixth-generation mobile communications. These topics are likely to help drive innovation and the further development of IoV technologies and contribute to smart transportation, smart cities, and other applications. On the basis of the present results, this paper offers several predictions regarding the future of research regarding the IoV. Full article

Quality communication is a major challenges in large-scale and distributed smart grid applications. Several protocols and middleware have been proposed to address communication quality issues in those applications. DDS is a standard data-centric middleware for publish/subscribe communication. It has been proposed for smart grid to address both connectivity and communication quality issues. DDS provides multiple quality of service (QoS) policies to address reliability, latency, and data availability. One of the main challenges in adopting the standard in smart grids is the complexity of adopting and tailoring its QoS policies. This is because those policies are described informally introducing ambiguities, which hinders the precise implementation of DDS. To address this, we formalize the descriptions of DDS QoS policies using the object constraint language (OCL). We also clearly defined the design structural relations among DDS entities and QoS policies. In the process, we analyzed the dependencies among QoS policies and we built clear and concise structural relations. We then proposed feature modeling and a management layer to facilitate QoS tuning and to reduce development and configuration complexity. We implemented the proposed approach in a simulated power consumption domain. The results show that the approach improves the development process. They also show that the approach significantly improves the performance of DDS-enabled applications. Full article

Next-generation Internet-of-Things applications pose challenges for sixth-generation (6G) mobile networks, involving large bandwidth, increased network capabilities, and remarkably low latency. The possibility of using ultra-dense connectivity to address the existing problem was previously well-acknowledged. Therefore, placing base stations (BSs) is economically challenging. Drone-based stations can efficiently address Next-generation Internet-of-Things requirements while accelerating growth and expansion. Due to their versatility, they can also manage brief network development or offer on-demand connectivity in emergency scenarios. On the other hand, identifying a drone stations are a complex procedure due to the limited energy supply and rapid signal quality degradation in air-to-ground links. The proposed method uses a two-layer optimizer based on a pre-trained VGG-19 model to overcome these issues. The non-orthogonal multiple access protocol improves network performance. Initially, it uses a powerful two-layer optimizer that employs a population of micro-swarms. Next, it automatically develops a lightweight deep model with a few VGG-19 convolutional filters. Finally, non-orthogonal multiple access is used to schedule radio and power resources to devices, which improves network performance. We specifically examine how three scenarios execute when various Cuckoo Search, Grey Wolf Optimization, and Particle Swarm Optimization techniques are used. To measure the various methodologies, we also run non-parametric statistical tests, such as the Friedman and Wilcoxon tests. The proposed method also evaluates the accuracy level for network performance of DBSs using number of Devices. The proposed method achieves better performance of 98.44% compared with other methods. Full article

Wearable wireless biomedical sensors have emerged as a rapidly growing research field. For many biomedical signals, multiple sensors distributed about the body without local wired connections are required. However, designing multisite systems at low cost with low latency and high precision time synchronization of acquired data is an unsolved problem. Current solutions use custom wireless protocols or extra hardware for synchronization, forming custom systems with high power consumption that prohibit migration between commercial microcontrollers. We aimed to develop a better solution. We successfully developed a low-latency, Bluetooth low energy (BLE)-based data alignment method, implemented in the BLE application layer, making it transferable between manufacturer devices. The time synchronization method was tested on two commercial BLE platforms by inputting common sinusoidal input signals (over a range of frequencies) to evaluate time alignment performance between two independent peripheral nodes. Our best time synchronization and data alignment method achieved absolute time differences of 69 ± 71 μs for a Texas Instruments (TI) platform and 477 ± 490 μs for a Nordic platform. Their 95th percentile absolute errors were more comparable—under 1.8 ms for each. Our method is transferable between commercial microcontrollers and is sufficient for many biomedical applications. Full article

Wireless wearable sensor systems for biomedical signal acquisition have developed rapidly in recent years. Multiple sensors are often deployed for monitoring common bioelectric signals, such as EEG (electroencephalogram), ECG (electrocardiogram), and EMG (electromyogram). Compared with ZigBee and low-power Wi-Fi, Bluetooth Low Energy (BLE) can be a more suitable wireless protocol for such systems. However, current time synchronization methods for BLE multi-channel systems, via either BLE beacon transmissions or additional hardware, cannot satisfy the requirements of high throughput with low latency, transferability between commercial devices, and low energy consumption. We developed a time synchronization and simple data alignment (SDA) algorithm, which was implemented in the BLE application layer without the need for additional hardware. We further developed a linear interpolation data alignment (LIDA) algorithm to improve upon SDA. We tested our algorithms using sinusoidal input signals at different frequencies (10 to 210 Hz in increments of 20 Hz—frequencies spanning much of the relevant range of EEG, ECG, and EMG signals) on Texas Instruments (TI) CC26XX family devices, with two peripheral nodes communicating with one central node. The analysis was performed offline. The lowest average (±standard deviation) absolute time alignment error between the two peripheral nodes achieved by the SDA algorithm was 384.3 ± 386.5 μs, while that of the LIDA algorithm was 189.9 ± 204.7 μs. For all sinusoidal frequencies tested, the performance of LIDA was always statistically better than that of SDA. These average alignment errors were quite low—well below one sample period for commonly acquired bioelectric signals. Full article