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Journal = Reports
Section = Gastroenterology

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6 pages, 2341 KiB  
Case Report
Endoscopic Guided Dilations without Intralesional Corticosteroid Injections: Pediatric Crohn’s Patients Case Series
by Leo Fawaz, Yousif Slim and Peter N. Freswick
Reports 2024, 7(4), 81; https://doi.org/10.3390/reports7040081 - 24 Sep 2024
Viewed by 1053
Abstract
Background and Clinical Significance: The treatment for pediatric Crohn’s disease (CD) has shifted over the years from steroids and immunomodulators to biologics with the goal of histological and clinical remission. Endoscopic balloon dilation (EBD) has been utilized for stricturing disease, even in the [...] Read more.
Background and Clinical Significance: The treatment for pediatric Crohn’s disease (CD) has shifted over the years from steroids and immunomodulators to biologics with the goal of histological and clinical remission. Endoscopic balloon dilation (EBD) has been utilized for stricturing disease, even in the pediatric population. EBD has been shown to be effective and minimally invasive, though historically, has been performed on patients with persistent mucosal inflammation. As such, intralesional corticosteroid (ILC) injections have been traditionally utilized during EBD. However, intralesional corticosteroid efficacy among pediatrics patients in deep endoscopic remission is unknown. Case Presentation: We report four patients that demonstrated at least initial successful dilations without intralesional steroid injections. Conclusions: The use of ILC injections during routine EBDs in pediatric patients should be further explored in randomized control trials. Full article
(This article belongs to the Section Gastroenterology)
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Figure 1

Figure 1
<p>Patient 3 initial stricture of right colon (2020).</p>
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<p>Patient 3 February 2021; 7 mm stricture pre-dilation.</p>
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<p>Patient 3 February 2021; dilation 7–15 mm.</p>
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<p>Patient 3 February 2021; 15 mm stricture post-dilation.</p>
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<p>Patient 3 August 2021; dilation to 20 mm.</p>
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