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Search Results (2)

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Journal = Reports
Section = Epidemiology/Public Health

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9 pages, 452 KiB  
Article
Clinical and Epidemiological Characteristics of Chikungunya and Dengue Infections in Provincial Hospitals of Davao de Oro, Philippines
by Nestor Arce, Kobporn Boonnak, Lee Thunder Bernasor, Christian Joy Salas, Anastasia Putri, Pyae Linn Aung, Hisham Ahmed Imad, Wirongrong Chierakul, Viravarn Luvira, Benjaluck Phonrat, Weerapong Phumratanaprapin and Prakaykaew Charunwatthana
Reports 2024, 7(4), 112; https://doi.org/10.3390/reports7040112 - 11 Dec 2024
Viewed by 725
Abstract
Background: Mosquito-borne diseases such as dengue and chikungunya are endemic to tropical regions and are common causes of acute febrile illness in both adults and children. The Philippines, home to more than one hundred million residents and visited by several million tourists each [...] Read more.
Background: Mosquito-borne diseases such as dengue and chikungunya are endemic to tropical regions and are common causes of acute febrile illness in both adults and children. The Philippines, home to more than one hundred million residents and visited by several million tourists each year, is one such region where the risk of these diseases is endemic. Objective and Methods: To better understand the detailed situation, we estimated the proportion of these diseases in the community by conducting a prospective observational study in four provincial hospitals of Davao de Oro, Philippines, from February 2019 to February 2020. Sera from 382 study participants were used for laboratory confirmation of dengue or chikungunya by serology. Results: Dengue was diagnosed in 57.1%, chikungunya in 7.07%, and coinfection with both dengue and chikungunya in 7.3%, while the etiology was undetermined in 35.9% of the study participants. Common clinical symptoms included fever, headache, and a rash, which were overlapping symptoms that were clinically indistinguishable at the presentation to the hospital, necessitating laboratory diagnostics. Conclusions: The identification of the presence of chikungunya in Davao de Oro calls for increased awareness, improved diagnostics, and integrated disease control measures to manage outbreaks that can occur in dengue-endemic regions. Full article
(This article belongs to the Section Epidemiology/Public Health)
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<p>The proportions of positive serology for dengue and chikungunya among 382 patients with acute undifferentiated febrile illness.</p> Full article ">
8 pages, 1884 KiB  
Case Report
Prolonged Neurological and Musculoskeletal Symptoms Following Shingrix Vaccination
by Sabrina Hollar, Amna Khalid, Benjamin D. Brooks and Michael Wons
Reports 2024, 7(4), 83; https://doi.org/10.3390/reports7040083 - 9 Oct 2024
Viewed by 1645
Abstract
Background and Clinical Significance: The recombinant zoster vaccine (Shingrix) helps prevent shingles and its complications in adults 50 and older. While minor side effects are common, severe adverse reactions are thought to be rare, and long-term side effects are not well documented. [...] Read more.
Background and Clinical Significance: The recombinant zoster vaccine (Shingrix) helps prevent shingles and its complications in adults 50 and older. While minor side effects are common, severe adverse reactions are thought to be rare, and long-term side effects are not well documented. Case Presentation: A 50-year-old woman with Crohn’s disease developed joint pain, effusion, and neurological symptoms such as numbness and tingling shortly after receiving the first dose of the recombinant zoster vaccine. Symptoms waxed and waned but persisted for over a year despite anti-inflammatories and specialist referrals. Diagnostic imaging and labs were unrevealing. Conclusions: This case of prolonged somatic and neurological symptoms associated temporally with Recombinant zoster vaccine administration reinforces the critical need for thorough pharmacovigilance and investigation of possible long-term adverse vaccine reactions. Provider documentation and reporting of individual experiences can help improve the detection of rare vaccine-related risks, elucidate potential risk factors, and refine safety screening. Diligent monitoring and research into longitudinal vaccine outcomes remain paramount, especially following recent emergency authorizations. Full article
(This article belongs to the Section Epidemiology/Public Health)
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<p>(<b>a</b>) Enlarged, warm, and erythematous injection site on the patient’s left deltoid post vaccination day 2 (<b>b</b>) An alternate angle of the patient’s left deltoid reaction post vaccination.</p> Full article ">Figure 2
<p>(<b>a</b>,<b>b</b>) Depictions of the patient’s swollen knees in a seated position (swelling on left, without swelling on the right); (<b>c</b>,<b>d</b>) a comparison of the patient’s knees when swollen (top picture) vs. without swelling (bottom), with figure (<b>c</b>) depicting swollen knees and figure (<b>d</b>) depicting knees without swelling.</p> Full article ">Figure 2 Cont.
<p>(<b>a</b>,<b>b</b>) Depictions of the patient’s swollen knees in a seated position (swelling on left, without swelling on the right); (<b>c</b>,<b>d</b>) a comparison of the patient’s knees when swollen (top picture) vs. without swelling (bottom), with figure (<b>c</b>) depicting swollen knees and figure (<b>d</b>) depicting knees without swelling.</p> Full article ">
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