The Carlton Crew deal with internal affairs, Tony Mokbel builds an empire while Detective Inspector Jim O'Brien finds a way to get eyes and ears on Mokbel. Carl Williams is injured in a dispute with the Morans and swears revenge.
Tony and the Carlton Crew import a huge hash shipment; the Victoria Drug Squad shares intelligence with Australian Federal Police agent Jarrod Ragg in a bid to bring down Mokbel and the Carlton Crew.
When a hitman alleges Tony is involved in murder, Tony decides to skip bail and become Australia's most wanted man. Tony takes a massive gamble when he recruits a pair of cleanskins to run his drug empire while he is on the run.
After skipping bail, Tony hatches a risky plan to flee Australia and start a new life in Greece. With Tony on the run, the fight is on for control of his drug empire. The police face a wall of silence in their search for Fat Tony.
Tony fights sea-sickness as he sails from Perth to Athens to avoid capture by the police. Tony's pregnant girlfriend is followed by police as she travels through Europe to meet him. The police manhunt finally gets a break-through.
Tony has managed to gain a major victory over the police, but he believes that his former mate Carl Williams has betrayed him. Carl's double-dealings with the police don't go to plan after he is brutally murdered by a another inmate.