Goofs

Right after the spaceship crashes in Laos, the four main characters emerge from a cave and stare into the river. When they decide to jump into the river, Audrey takes her shirt off and leaves her tank top on. She is then wearing the shirt again, only for it to be gone soon thereafter.

Mark's 8th shotgun blast produced no visual blast.

When the missile hits LA and one sees a shock wave and pyroclastic-type wall which level the city. Minutes later the are tall building standing and an unscathed, pristine marina.

Mark places the lit flare, fuse first, into the car's gas tank. The explosion would have been instantaneous.

No police department would store a loaded shotgun under the front desk.

Mark would not have been able to fire the shotgun 9 times without reloading. Shortly thereafter, Trent then fired the weapon without reloading.

Events in this movie are concurrent with that of the first Skyline film. Presumably, both films are set in 2010, though that was never fully established; only assumed. The terror organization ISIS is mentioned in this film, even though ISIS was not considered a global threat in 2010. However, ISIS was founded in 1999 by Jordanian Salafi. The roots of ISIS trace back to 2004, when the organization known as Al Qaeda in Iraq formed. Abu Musab Al-Zarqawi, who was originally part of Osama bin Laden's Al Qaeda Network, founded this militant group.

When the baby went from an infant to a toddler, she has been dressed accordingly before anyone knew she had changed.

At 39:50, Mark is holding the newborn wrapped in his t-shirt and you can clearly see the baby is wearing a diaper.

The main characters are taken aboard the spaceship in Los Angeles. After the ship crashes, they get out and they're in a completely different location: Laos. Yet none of them wonder where they are.

(at the 16 minute mark) Mark, the "seasoned" detective, asks his for a hand gun, then asks for more "clips". No trained detective, or any person knowledgeable about guns, would call magazines for a handgun "clips".