Tom Cruise admitted to being terrified at the prospect of being in a musical but saw it as a personal challenge to be overcome.
Poison and Def Leppard performed live at the premiere with a Bourbon Room backdrop on the stage. Def Leppard dedicated their song Pour Some Sugar On Me to "our good friend Stacee Jaxx."
Patricia Whitmore (Catherine Zeta-Jones) leads a religious group called Ladies Organization to Stop Evil Rock Singers. The initials spell out the acronym LOSERS.
Kevin Cronin: lead singer of the band REO Speedwagon, singing "We Built This City" with the people supporting The Bourbon Room.
Nuno Bettencourt: guitarist/vocalist for the band Extreme (whose song "More Than Words" is featured in the film), singing "We Built This City" with the supporters of The Bourbon Room.
Sebastian Bach: the former lead singer of Skid Row is in the crowd next to Russell Brand during "We Built This City/We're Not Going To Take It." Skid Row's song "I Remember You" is heard playing in the Tower Records store while Drew and Sherrie are shopping.