Trivia

The gas station set was built on location in Morocco. It was so authentic that occasionally someone not involved in the production would stop to buy gas.

The mutants were created by CGI, physical effects or both. Most of the mutants with full deformations were created by prosthetic makeup. But the deformed children who were playing were digitally distorted using tracking dots on their faces. Ruby was a mixture of the two, using the tracking dots for distortion and prosthetic teeth.

Almost all of Ted Levine's actions and lines were improvised.

(at around 3 mins) The photos of mutations that play during the opening credits are not of atomic mutation, but birth defects caused by the use of Agent Orange in Vietnam.

Make-up artist Greg Nicotero was featured as Cyst, the mutant with the halo head-gear.