The 3rd highest grossing film of 2006, and the highest grossing animated film of 2006.
Originally this film was set for a November 2005 release but was moved to March 2006, due to the events of Hurricane Katrina and due to Robots (2005) being released earlier in that year.
The flashback in the movie was originally going to focus on Manny's conflict with his first family. However, Queen Latifah pitched the idea of the flashback in the film to center more on Ellie's origins.
Made double of what the first film made in the box office.
Animation took a relatively speedy eight months.