Brendan Fraser was set to play the role of Dr. Steve/Eddie, but scheduling conflicts with filming the movie Bedazzled (2000) prevented him.
Franny's Mother, played by Joanna Gleason, sings very badly in the movie and is asked numerous times by her daughter not to sing. In fact, Gleason has a very good singing voice and has appeared in several Broadway musicals, including "Into the Woods" for which she won the 1988 Tony Award for Best Actress in a Musical.
Bree Turner, who plays the bride needing comforting by Jennifer Lopez at the beginning of the movie, also opened another wedding movie, as a bridesmaid in the opening title sequence performance in My Best Friend's Wedding (1997). Fan theories claim it was her playing the same character, still unlucky in love.
Jennifer Love Hewitt was developing a separate film with the same premise for her to star in but was forced to cancel the project when this film was released.
Mary's boss, Geri, is married to the best man that Mary fed the toast to in real life.