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In 2275, a team of bounty hunters tries to stop a conspiracy involving alien DNA. In 2300, bounty hunter Travis Montana searches for his lost son.

Dante agrees to transport Rudolpho's friend Stephen Hamilton and his two daughters Ayla and Cordula. However, Dante is unaware that Hamilton is being blackmailed by the Orchard to spy on him. Meanwhile, Percy befriends the daughters and clashes with Dante over a new addition to the Tulip's security system.

Dante is kidnapped by ruthless Orchard agent Tosca, who believes that Dante's missing son Travis holds the key to The Divinity Cluster and hence needs to probe Dante's mind in order to find him. Meanwhile, Percy has her hands full as she tries to stop an evil version of Caravaggio from blowing up the Tulip.

Colonel E.W. Bramwell gets awakened after spending 50 years in cryogenic slumber. However, Bramwell still believes that Earth is at war with the Raiders. Dante plans to use Bramwell's legendary status with the Raiders as a means to find his son Travis.

Percy gets arrested after she assaults a bounty hunter who's a member of the rival group the Oberen Militia. Oberen Militia leader Rex uses Percy's arrest to blackmail Dante into freeing her brother Goran from a Neried prison.

Dante is reunited with Ike, an old friend who was a rival for Dante's deceased wife Penny's affections. Ike's shady business partner Marco works with the Raiders to locate special seeds that can grow in any climate. Meanwhile, Percy suspects that Lucretia has a hidden agenda.

The crew of the Tulip receive a radio transmission from a religious cult who are planning to commit mass suicide by crashing their ship into the sun. Lucretia winds up falling under the unnatural influence of charismatic cult leader Brother #13.

Dante arrests murderess Dr. Nasreen and her browbeaten teenage son Ajit. Unbeknownst to Dante, Nasreen possesses a device that can control his mind.

Tension and mistrust mounts among the crew members of the Tulip with the addition of Dante's son Travis as a reluctant new member, and Eccleston returns from "the dead" with a dire warning about The Divinity Cluster.

Dante and Lucretia capture Petrakis, a vicious escaped prisoner who has hijacked a luxury yacht. However, the Tulip gets commandeered by a Special Ops squad who are transporting Ire, a young girl with unique powers who might be infected with a deadly virus.

After Rudolpho sells the Tulip to weaselly businessman Max for conversion into a prison ship, Dante must infiltrate Max's organization while fending off the unwanted advances of Max's amorous wife Zelda.

Dante and Lucretia try to capture Novak, a ruthless war criminal who's responsible for sacrificing thousands of innocent people to the Divinity Cluster. Meanwhile, Percy and Caravaggio have their hands full contending with Billy Ray, a blithely malevolent holographic computer virus that's wreaking havoc on board the Tulip.

Percy ignores the warnings of both Dante and Lucretia when she decides to befriend one of a pair of cousins that the crew of the Tulip are transporting to an automated prison on Mercury.

Dante and Lucretia encounter a Raider with a boy who might be Dante's missing son while hunting a pair of con artists on Mars. Meanwhile, back on the Tulip Percy gets trapped in Dante's virtual reality device that simulates his dead wife Penny.

Dante is reunited with McDuff, an old friend who's dying of cancer. Meanwhile, Lucretia's father Darius Scott asks her to capture unstable geneticist Eccleston, who holds the secret to an alien gene known as The Divinity Cluster.

Scientist Harman, a former associate of Darius Scott, becomes one of the most wanted men in the universe after he develops superhuman speed and refuses to talk to anyone but Darius about this. Dante's and Percy's suspicions about Lucretia come to a head when she helps Harman escape from the Tulip.

The Tulip is diverted to search for survivors after an accident at a secret research station on Triton. When the Tulip gets disabled by the station's graviton experiment, Dante stumbles on a time loop that gives him multiple chances to prevent Percy's death from oxygen deprivation.

Darius boards the Tulip to help Lucretia inform Dante about the Divinity Cluster.

Dante, Lucretia, and Percy all find themselves caught in separate Bubble Universes as the result of a graviton experiment on a Triton research station that's gone haywire, and each one of them has to outwit different versions of Five, an insane serial killer who's a prisoner on board the Tulip.

While transporting wily con artist Etienne to prison, the Tulip receives a distress call from Dr. Devon. It turns out that Devon is being pursued by a band of Raiders after freeing his psychically gifted son Ryan from an Orchard research facility.

Darius pulls strings with Rudolpho to have the Tulip transport Andrea Arquette, an artist who's suspected of murder. Percy discovers that the Tulip is being trailed by a cloaked ship that might be over three million years old.

Rudolpho instructs the crew of the Tulip to pick up a murder suspect who turns out to be Lucretia's ex-husband Eric, who has escaped from an Orchard medical facility where he was injected with an experimental antibody that has killed all previous recipients within 48 hours.

The Tulip receives a cryptic message from Percy that leads Dante to the special seeds that are concealed in her quarters. Dante is reunited with his son Travis, who reveals his mother Penny's role in early experiments with The Divinity Cluster.