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Teens encounter people, who, after being used as guinea pigs for the experimental testing of a virus can live forever in a post apocalyptic world.

A shy, obsessive comic book fan gets injected with an experimental serum of a lab that is studying how to give humans the abilities of spiders. At first he develops minor abilities such as increased strength, which allows him to fight local criminals and bullies, thus living out his dream of being a superhero, and impressing his attractive next-door neighbor. Things start to get more odd when he is able to shoot webs out of his abdomen. Then he loses control over the force with which he applies his increasingly deadly abilities, as well as his judgment to discern between criminals and jokesters. His dream becomes a nightmare when he starts growing large spider body parts, he's in constant pain, and he develops a nearly insatiable hunger. A detective with a traumatized wife begins investigating when bodies covered in cobwebs and spider venom start piling up.

In Ireland, two carnies abduct a mermaid and decide to take her to America. In their sea route, the seductive and mysterious creature reveals an uncontrollable darker side.

An evil video game comes to life and hunts the group of developers.

When a killer alien creature, who is misunderstood, begins killing specific members of a small town, a school psychologist learns of its link to a young boy's tragic childhood, and his adoptive father's dark secret.