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KEGG   Phascolarctos cinereus (koala): 110212016
Entry
110212016         CDS       T05867                                 
Symbol
ACACA
Name
(RefSeq) acetyl-CoA carboxylase 1 isoform X1
  KO
K11262  acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
Organism
pcw  Phascolarctos cinereus (koala)
Pathway
pcw00061  Fatty acid biosynthesis
pcw00620  Pyruvate metabolism
pcw00640  Propanoate metabolism
pcw01100  Metabolic pathways
pcw01212  Fatty acid metabolism
pcw04152  AMPK signaling pathway
pcw04910  Insulin signaling pathway
pcw04922  Glucagon signaling pathway
pcw04936  Alcoholic liver disease
Module
pcw_M00082  Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:pcw00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    110212016 (ACACA)
   00640 Propanoate metabolism
    110212016 (ACACA)
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    110212016 (ACACA)
  09110 Biosynthesis of other secondary metabolites
   00254 Aflatoxin biosynthesis
    110212016 (ACACA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    110212016 (ACACA)
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    110212016 (ACACA)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    110212016 (ACACA)
Enzymes [BR:pcw01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.15  acetyl-CoA carboxytransferase
     110212016 (ACACA)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.14  biotin carboxylase
     110212016 (ACACA)
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.2  acetyl-CoA carboxylase
     110212016 (ACACA)
SSDB
Motif
Pfam: ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_N Biotin_carb_C Biotin_lipoyl ATP-grasp Dala_Dala_lig_C ATP-grasp_3
Other DBs
NCBI-GeneID: 110212016
NCBI-ProteinID: XP_020847432
UniProt: A0A6P5KRG5
LinkDB
Position
Unknown
AA seq 2338 aa
MDEPSPVAKPLELNQRSRFIIGSVSEDNSEDEISSLVKLDLLEEKEGSLSPASVSSDTLS
DLGLPSLQDGLALPMRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEK
VLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPG
GPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWAL
GDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQDLYEKGYVKDVDAGLQA
AEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEV
QILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPVVFEHMEQCAVKLAKMVGYVSA
GTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMY
GVSPWGDVPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGY
FSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLET
ESFQHNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSVSNFLHSLERGQV
LPAHTLLNTVDVELIYEGAKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDG
SSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVLRSPSAGKLIQYIVEDGGHVFAGQCYA
EIEVMKMVMTLISVESGCIHYVKRPGAALDPGCVIAKLQLDNPSKVQQAELHTGSLPKIQ
STALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSNRVKDWVERLMKTLRDPSLPLLELQ
DIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREV
FFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFTLREENKSD
MNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALR
ARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYH
SNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRMSFSSNLNH
YGMAHVASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSPPQSPTFPE
AGHTSLYDEDKAARDEPIHILNVAIKTDCDIEDDRLAAMFRDFTQQNKAALVEHGIRRLT
FLVAQKDFRKQVNCEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRN
FDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGER
LLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRV
LQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPL
HGMLINTPYVTKDLLQSKRFQAQTLGTTYIYDIPEMFRQSLIKLWESMSAQAFLPAPPLP
SDMLTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTLKSPEYPEGRDIIVIGNDITYRI
GSFGPQEDMLFLRASELARAEGIPRIYVAANSGARIGLAEEIRHMFHVAWVDPDDPYKGY
KYLYLTPQDFKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGSGMIAGESS
LAYDEIITISLVTCRAIGIGAYLVRLGQRTIQVENSYLILTGAAALNKVLGREVYTSNNQ
LGGIQIMHNNGVTHSTVCDDFEGVLTVLHWLSYMPKNVRSPVPLLNSKDPIDRIIEFVPT
KAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAV
ETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPLMVFANWRG
FSGGMKDMYDQVLKFGAYIVDGLRECCQPVMVYIPPQAELRGGSWVVIDPTINPRHMEMY
ADRESRGSILEPEGTVEIKFRRKDLVKTMRRVDPVYIRLAERLGTPELSPAERKELESKL
KEREEFLIPIYHQVAVQFADLHDTPGGMQEKGVINDVLDWKTSRTFFYWRLRRLLLEDLV
KKKIHAANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTEEDGFRSVV
DENIKYISRDYILKQIRSLVQANPEVAMDSIIHITQHISPTQRAEVVRILSTMDSPSA
NT seq 7017 nt   +upstreamnt  +downstreamnt
atggatgagccttctcctgtggccaagcctctggagctgaaccagcgctctcgattcata
attggctctgtgtccgaagataactctgaggatgagatcagcagtttggtgaaactggat
ctgctggaagagaaagaaggatctttgtcaccagcttctgtcagctcagatactctctct
gacctgggactcccaagcctacaagatggcttggccttacccatgaggtccagcatgtcc
ggcctacacctggtaaaacaaggccgagaccgaaagaaaatagactcccagagagatttc
actgttgcttctccagcagagtttgttactcgttttgggggaaataaagtgattgaaaag
gttctcattgccaacaatggcattgctgcagtgaaatgcatgagatctatccgtaggtgg
tcttatgagatgtttcgaaatgaacgtgcaatccgatttgttgtcatggtgacgcctgaa
gatcttaaagcgaatgcagagtacattaagatggcagatcactacgtcccagtgcctgga
ggacctaacaacaataactatgcaaatgtggaactaattcttgatattgctaaaaggatc
ccagtacaagcagtatgggctggatggggccatgcttctgaaaaccctaagcttcccgaa
ctcctcttaaagaatggcattgcctttatgggtcctccaagccaagccatgtgggctctg
ggggataagattgcctcttctatagtagctcaaacggcaggtatcccaactcttccctgg
agtggcagtggtcttcgtgtggactggcaagagaatgatttttcaaagcgcattttgaat
gttccccaggatctgtatgagaaaggttatgtgaaggatgtagatgctggattgcaggca
gctgaggaagttggttatccagttatgatcaaggcctcagaaggaggaggagggaaggga
atcagaaaagtgaacaatgcagatgacttccctaacctcttcagacaggttcaggctgaa
gtccctggctcccctatctttgtgatgagactggccaaacagtctcgtcacttggaggtg
cagatcttagcagatcagtatggcaatgcaatctccttgtttggtcgtgactgctctgtg
cagcgaagacatcagaagatcatagaagaggctcctgccactattgcaactccagtggta
tttgagcatatggaacagtgtgctgtgaagcttgccaagatggtaggttatgtcagtgct
gggactgtggagtacctctacagccaggatggcagcttctacttcctggagctgaatccg
cggctgcaggtggagcatccttgtacggagatggtggctgatgtcaaccttccagcggcc
caactccagattgccatgggtattcctctgtacagaattaaagatatccgaatgatgtat
ggggtctcaccctggggagacgtaccaattgattttgaaaactctgctcatgtcccctgc
ccgaggggtcacgtcatcgctgctcggatcactagtgagaatcctgatgagggttttaag
cccagctcaggaacagtccaggagttgaatttccgtagcaataagaatgtctggggctat
ttcagtgttgctgctgctggtggacttcatgaatttgcagattctcagtttggtcactgc
ttctcctggggagaaaaccgagaggaggccatttcaaacatggtggtggctttgaaggag
ctgtctatccggggagacttccggactactgttgagtacctgatcaagctgctggagacg
gagagcttccagcataaccgcatagacacgggctggctagacaggctgatcgctgagaaa
gtacaggcagagcgtcctgataccatgttgggggttgtatgtggggctctacatgtggca
gatgtgagccttcggaacagtgtctccaatttccttcactctttagagaggggtcaggtc
cttcctgctcacacacttctgaacacagttgatgttgagcttatctacgaaggggccaaa
tatgtgctgaaggtgacccggcagtcccctaactcatatgtggtgatcatgaatggctcc
tgtgtggaggtggatgtgcaccgtctgagtgatggaggattacttttgtcttatgatggt
agcagctatacaacatacatgaaggaagaagtggataggtaccgtatcacaattggcaac
aagacctgtgtatttgagaaggagaatgacccatctgtactccgttcaccttctgctgga
aaattgatccagtacattgtggaggatggaggccatgtgtttgctggccagtgctatgct
gagattgaggtaatgaagatggtaatgactttaatatctgttgagtctggttgtatccac
tatgtcaagcggcctggagcagctcttgaccctggttgtgtgattgccaagttgcagctg
gataaccccagtaaggttcagcaggctgagctacatactggaagtttgcccaagatccag
agtacagcactcagaggcgagaagcttcatcgagtcttccattatgtcctggataacctg
gtcaatgtaatgaatggatactgcctcccggaccctttctttagcaacagggtaaaagat
tgggtggagagattgatgaaaaccctcagagacccttccctacctctcctagaattgcag
gacattatgaccagtgtttctggccggataccccccaatgtggagaagtccatcaagaag
gaaatggcccagtatgccagcaatatcacctctgttctttgccagtttcccagccagcag
atcgccaacatcctagacagtcatgcagctacattgaaccggaagtctgaacgagaagtc
ttcttcatgaacactcagagcattgtgcagctggtccagaggtaccgaagtggtatcaga
ggccacatgaaagctgtggtgatggatctgctccgacagtacctgcgagtggagactcag
ttccagaatggtcactatgataagtgtgtcttcaccctccgggaagagaataaaagtgat
atgaacactgtgctgaactatatcttctcccatgctcaagtcaccaagaagaaccttctg
gtcacaatgcttattgatcagttgtgtggccgggatcccaccctcactgatgagctgctg
aatatccttaccgagctgactcagcttagcaaaaccaccaatgctaaagtggcacttcga
gcccggcaggttcttattgcctcccatttaccatcctatgaacttcgacataaccaagta
gaatctattttcctatcggctattgacatgtacggacatcagttttgcattgagaaccta
cagaaacttatcttgtctgaaacatccatttttgatgtcctcccaaacttcttctaccat
agcaaccaagtggtgagaatggcagctctggaggtgtatgtgcggagggcctacattgcc
tatgaactcaacagtgtccaacatcgacaactgaaggacaatacctgtgtggtagagttc
cagttcatgctgcccacatctcacccaaacagaatgtccttctcctccaacctcaaccac
tatggcatggctcacgtagctagtgtcagcgatgtactactggacaactcattcactcca
ccgtgccagaggatgggcgggatggtttctttccggactttcgaagactttgtcagaatt
tttgatgaagtaatgggctgtttctgtgactccccaccccaaagccctacattccctgag
gcgggccacacttcgctgtatgatgaagataaggctgccagggatgaacccattcacatc
ctgaacgtggccatcaagactgactgtgacattgaggatgacagactagcagccatgttt
agagattttactcagcaaaataaagctgctcttgttgagcatggaatccggcggcttact
ttcctggttgcacaaaaggatttcagaaaacaggtcaactgtgaggtggatcaaagattt
catagagagtttcctaaatttttcacattccgagcaagggataagtttgaggaagatcgt
atctatcgtcacttggagcctgccctggctttccagctggagctaaaccgaatgaggaat
tttgacctcactgccattccatgtgccaaccacaagatgcatttataccttggggcagcc
aaagtggaagtgggcactgaagtgacagactatagattctttgtgagggcaatcatcagg
cattctgatctggtcaccaaggaagcctcttttgagtatctgcagaatgagggggaacgt
ctgctcctggaagccatggatgagttggaggttgcttttaacaataccaacgtccgaact
gattgcaaccatatcttcctcaactttgtgcccacggtcatcatggacccatcaaagatt
gaggaatctgtgaggagcatggtgatgcgctatggaagccggctgtggaaactccgagtc
ctccaagcagagttgaaaattaacatccgcttaacaccaactggaaaagcaattcccatc
cgcctcttcttgaccaatgagtctggttattacttggacatcagtctatataaggaagtg
acagactccaggacagcacagatcatgttccaggcatatggagacaaacagggaccactg
catggaatgttgatcaatactccctatgtgaccaaagacctgctacaatccaagaggttc
caagcacaaactttagggacgacatatatttatgatattccagaaatgttccggcagtct
ctgataaaactctgggaatctatgtcagctcaagcattcctgccagccccaccactgcct
tctgatatgctgacttatactgagctggtgttggatgatcaaggtcagctggtgcacatg
aacaggcttccaggaggaaatgagattggcatggtagcctggaaaatgactctgaagagt
cctgagtacccagaaggacgagatatcattgttattggaaatgacatcacctatcgaatt
gggtcctttggacctcaagaagatatgctatttctgagggcttctgagcttgccagggca
gagggtatccctcgcatttatgtggcagctaacagtggagcgagaattggattggcagag
gaaatacgccacatgttccatgtggcgtgggtggatcctgatgatccttacaagggatac
aagtatttatatttgactcctcaagattttaagagggtcagtgccctgaactctgttcac
tgtgagcatgtggaggatgaaggggaatccaggtataagataacagatattattggaaag
gaagaaggacttggggctgagaacctcaggggttctgggatgattgctggagaatcctca
ttggcatatgatgagatcatcaccatcagcctggtaacttgccgggccattggaattgga
gcttatctagtccgattggggcagaggaccatccaggttgagaactcatatttgattctg
accggagctgcagccctcaacaaagtgcttgggcgtgaagtatatacatctaataaccag
ctcggaggcatccagattatgcacaacaatggagtgactcacagtactgtatgtgatgac
tttgaaggggttcttacagtcctacattggctgtcttatatgcccaagaatgtgcgcagt
ccagttcctcttcttaactccaaggatcccatcgatagaatcattgaatttgtccctaca
aaggccccctatgatccccgctggatgctggcaggacgtcctcacccaacccagaaaggt
cagtggctaagtggattctttgactatggttccttctctgagatcatgcagccttgggca
cagacagttgtggttggtagagcccggctaggcggtatacctgtaggagtagttgctgta
gaaaccagaacagtggagctcagtatcccggctgatcccgccaacctggactctgaggcc
aagataattcagcaggcagggcaggtttggtttccagactctgcttttaagacctatcaa
gctatcaaggacttcaaccgggagggacttcccctcatggtctttgccaactggagaggc
ttctctggtggaatgaaagacatgtatgaccaggtcttgaagtttggagcttacatcgtg
gatggtttacgtgaatgctgtcaaccggtgatggtttacatccctccccaagctgagctc
cggggaggatcctgggttgttattgatcccaccattaacccccggcacatggaaatgtat
gctgaccgggaaagcagaggatctattctggagccagaggggacagtagaaatcaaattc
cgcagaaaggatttggtgaaaactatgcgtcgggtggacccagtgtacatccgcctggcc
gagcgattgggcaccccagagctaagcccagctgagcggaaggagttggagagcaaactg
aaggaacgggaagaattcctcattcccatttaccaccaggtagctgtgcagtttgctgac
ttgcatgacacaccgggcgggatgcaggaaaagggtgtcattaatgacgttctagactgg
aaaacatcccgcaccttcttctactggcgcctgaggcggctgctcttggaggacttagtg
aagaagaagatccacgcagccaatccggagctgacagacggccagatccaggccatgctt
aggcgctggtttgtggaggtggagggaacagtgaaggcttatgtctgggacaacaacaag
gacctggtggagtggctggagaagcagctgacagaggaagatggttttcgttcggtggtt
gatgaaaacatcaagtacatttcaagagattacatcctcaagcagatccgcagcttggtg
caggccaaccctgaggttgccatggattctatcatccacataacccaacacatctcacca
actcagcgggcggaagtggttcggattctctccacaatggactctccttcagcgtag

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