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KEGG   Orcinus orca (killer whale): 101279254
Entry
101279254         CDS       T05247                                 
Symbol
HDAC6
Name
(RefSeq) histone deacetylase 6 isoform X1
  KO
K11407  histone deacetylase 6 [EC:3.5.1.98]
Organism
oor  Orcinus orca (killer whale)
Pathway
oor04613  Neutrophil extracellular trap formation
oor05014  Amyotrophic lateral sclerosis
oor05034  Alcoholism
oor05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:oor00001]
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    101279254 (HDAC6)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    101279254 (HDAC6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    101279254 (HDAC6)
  09165 Substance dependence
   05034 Alcoholism
    101279254 (HDAC6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:oor01009]
    101279254 (HDAC6)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:oor03019]
    101279254 (HDAC6)
   04131 Membrane trafficking [BR:oor04131]
    101279254 (HDAC6)
   03036 Chromosome and associated proteins [BR:oor03036]
    101279254 (HDAC6)
Enzymes [BR:oor01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.98  histone deacetylase
     101279254 (HDAC6)
Protein phosphatases and associated proteins [BR:oor01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     101279254 (HDAC6)
Messenger RNA biogenesis [BR:oor03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Stress granule specific factors
     101279254 (HDAC6)
Membrane trafficking [BR:oor04131]
 Autophagy
  Aggrephagy
   Other aggrephagy associated proteins
    101279254 (HDAC6)
Chromosome and associated proteins [BR:oor03036]
 Eukaryotic type
  Histone modification proteins
   HDACs (histone deacetylases)
    Class II HDACs
     101279254 (HDAC6)
SSDB
Motif
Pfam: Hist_deacetyl zf-UBP zf-UBP_var LysX_preATP_grasp
Other DBs
NCBI-GeneID: 101279254
NCBI-ProteinID: XP_012392960
LinkDB
Position
X:43702288..43721235
AA seq 1149 aa
MTSTGQDSTTTRQRRSRHNPHPPAHDSSVTSVRPQTSKRGVKKGAVLRSSPNLAEVKKKG
RMKKLSQAAEQDLVVGLQGLDLNREARTLSGTGLVFDEQLNEFHCLWDDSFPEGPERLHA
IKEHLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSV
YLHPNSYTCACLASGSVLRLVDAVLRAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVA
ARYAQQKHDIQRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLTASNWST
TGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVSLEFQPQLVLVAAGFDALQGDPKG
EMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRSLAEGVSASLHTLLGDPCPVLEFPG
APCPSAQASISCALEALEPFWEVFVRSAETLEEEDTVEGDDVEEKEAEGPWQPPELPILT
WPVLQARTGLVYDPQMMDHYNLWDNHHPETPQRIKRIMHHLEELGLAGRCLALPARPATD
AELLTCHSAEHVDRLRATEKMKTRELHREGASYDSIYICPSTFTCAQLAAGAACRLVEAV
LAGEVLNGIAVVRPPGHHAERDAACGFCFFNSVAVAARHAQAVSGRALRILIVDWDVHHG
NGTQHIFEEDPSVLYISLHRYDHGAFFPMGDEGASSQIGQAAGTGYTVNVAWNGPRLGDA
DYLVAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGSCQVSPEGYAHLTHLLMGLANGR
IILILEGGYNLTSISESMAACTHSLLGDPPPLLTLLRPPLSGALASISETIQVHRRYWCS
LRVTKVKDKEGPSSSKLITKKAPQAANPLSAKGMTMPEGNILEAGTGKATSATSVKESTP
GQTTSETAVMEFTQDQSSETAMGGAAALNQATSEAATGDATLDQTTSEEAVGGAELIQSP
PASCTDNQTPPASPMQGATTQISPSKLTGNLRTLELDKAQEPPEEEELLGEAAGGQDMNE
SVLMHVTGDHADTDQAMFYAVTPLPWCPHLVAVCPVPEAGLDVTQPCQDCGALQENWVCL
SCYQVYCSRYINAHMLQHHEGSGHPLVLSYADLSTWCYHCQAYVHHKALLAVKNIAHQNK
FGENMLHSH
NT seq 3450 nt   +upstreamnt  +downstreamnt
atgacctccaccggccaggattccaccacaaccagacagcgaaggagtaggcacaatccc
catccccccgcccacgactccagcgtcacctcggtgagaccccagacctcgaagcgaggt
gttaaaaagggtgccgtactccgctccagccccaatctagcggaggtaaagaagaaaggc
agaatgaagaagcttagtcaagcagccgagcaagacctagtcgtggggctgcaagggctg
gatctgaaccgggaggccaggacactgtctggcactggcttggtgttcgatgagcagcta
aatgaattccactgcctctgggatgacagcttccctgaaggccctgagcggctccatgcc
atcaaggagcatctgatccaggagggcctcctggatcgctgtgtgtcctttcaggcccga
tttgccgaaaaggaggagctgatgttggttcacagtctagaatacattgatctgatggag
acgacccagtacatgaatgagggggaactccgtgtcctagcagatacctatgactcagtt
tatctgcatccgaactcatacacctgcgcctgcctggcctcaggctccgtcctcaggctg
gtggatgcagtcctgagggctgagatccggaatggcatggcgatcatcaggcctcctgga
caccatgcccagcacagtctcatggacgggtattgcatgttcaaccacgtggctgtggct
gcccgctatgctcaacagaagcatgacattcagagggtccttatcgtggattgggatgtg
caccacggtcaaggaacacagttcacctttgaccaagaccccagtgtcctctatttctcc
atccaccgctacgagcagggtcggttctggccccaccttacagcctccaactggtccacc
acaggttttggccaaggccagggatacaccatcaatgtgccttggaaccaggtggggatg
cgagatgccgactacatcgccgctttcctgcacgtcctgctgccagtttcccttgagttc
cagccccagctggtcctggtagctgctggatttgatgccctccaaggggaccccaagggc
gagatggccgccactccggcagggttcgcccagctaacccacctgctcatgggtctggca
ggaggcaagctgatcctctcactggagggtggctacaacctccgctccctggctgagggc
gtcagcgcctcgctccacacccttctgggagacccttgccccgtgctggagttccctggc
gccccttgcccgagtgcccaggcgtctatatcctgtgctctggaagcccttgagcccttc
tgggaggtcttcgtgagatcagctgagaccctggaggaggaggacactgtggagggggac
gatgtggaggagaaggaggcggagggaccatggcagccccctgagctcccaatcctgacg
tggccggtgctgcaggctcgcacagggctggtctatgacccacagatgatggatcactac
aacttgtgggacaaccaccaccccgagacgcctcagcgcatcaagcgtatcatgcaccac
ctggaggagttgggtcttgccgggcgctgtctcgccctgcccgcacgtccagccacggac
gctgagctgctcacctgccacagtgctgagcacgtggatcgtctgcgagccacggagaag
atgaagacccgggagctgcaccgcgagggcgccagctatgactccatctacatctgcccc
agcaccttcacctgtgcgcagctggctgctggcgccgcctgccgcctggtggaggctgtg
ctggcaggagaggttttgaatggcattgctgtggtacgtccccccggccaccatgcagag
cgggatgccgcttgcggtttctgcttcttcaactctgtggctgtggctgctcgccatgcc
caggccgtcagtgggcgtgcgctgcggatcctgatcgtggactgggacgtccatcatggt
aatggaactcagcacatatttgaggaggaccccagcgtgctgtacatttctctgcaccgc
tatgatcatggcgccttctttcctatgggggacgagggcgccagcagccagataggtcag
gctgcaggcacgggctacaccgtcaacgtggcctggaatgggccccgcttgggtgacgcc
gactacctggttgcctggcatcgtctggtgcttcccattgcctatgagtttaacccagaa
ctggtgctggtctcagctggctttgatgctgcccggggggacccactgggcagctgccag
gtgtcgcctgagggctatgcccacctcacccacctgctgatgggcctggccaatggccgc
attatccttatcctagagggtggttataacctgacatccatctcggagtccatggccgcc
tgcacccactccctccttggggacccgccacccctgctgaccctgctgcggcccccactg
tcaggggccctggcctcgatctccgagaccatccaagtccatcgcagatactggtgcagt
ttgcgggtcacaaaggtcaaagataaagagggaccctccagttctaagttgatcaccaag
aaggcaccccaggcagccaatcctttgtcagccaaggggatgaccatgccagaagggaac
attctggaggcaggcacagggaaggccacctcagcaacatctgtgaaagagtccactcca
ggccagactacgtcagagacagctgtgatggagttcactcaggaccagtcatcagagaca
gccatgggaggagctgctgcgctgaaccaggccacctcagaggcagccacaggggatgcc
acgctggaccagaccacctcggaggaggctgtggggggagctgagctgatccaaagccct
ccagcctcatgcactgacaatcagactcctccagcgtcacccatgcaaggagccacaacc
cagatatcccccagtaaactgactggaaatctcaggaccttggaactagacaaggcacag
gaacccccagaagaggaggagctactaggagaggcagctggaggtcaggacatgaatgag
tcagtactgatgcatgtcactggagaccatgctgacactgaccaagccatgttttatgct
gtaacaccactgccctggtgtccccatttggtggcagtatgccctgtacctgaagcaggc
ctggatgtgacccaaccttgtcaggactgtggagccctccaggagaactgggtgtgtctg
tcttgctaccaggtctactgcagtcgttacatcaatgcccatatgctccaacaccatgaa
ggctcgggacacccgctggtactcagctacgccgacctgtctacctggtgttaccactgt
caggcctacgttcaccacaaggctctcctagctgtgaagaacatcgcccaccagaacaag
tttggggagaacatgctccactcacactaa

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