KEGG T01001: 2521

Homo sapiens (human): 2521

Entry

2521              CDS       T01001

Symbol

FUS, ALS6, ETM4, FUS1, HNRNPP2, POMP75, TLS, altFUS

Name

(RefSeq) FUS RNA binding protein

K13098

RNA-binding protein FUS

Organism

hsa Homo sapiens (human)

Pathway

hsa03015

mRNA surveillance pathway

hsa03040

Spliceosome

hsa05014

Amyotrophic lateral sclerosis

hsa05022

Pathways of neurodegeneration - multiple diseases

hsa05202

Transcriptional misregulation in cancer

Network

nt06464 Amyotrophic lateral sclerosis

Element

N01156

FUS-regulated splicing

N01157

Mutation-caused aberrant FUS to FUS-regulated splicing

Disease

H00058

Amyotrophic lateral sclerosis (ALS)

H01577

Essential tremor

Brite

KEGG Orthology (KO) [BR:hsa00001]
09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    2521 (FUS)
  09122 Translation
   03015 mRNA surveillance pathway
    2521 (FUS)
09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    2521 (FUS)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    2521 (FUS)
   05022 Pathways of neurodegeneration - multiple diseases
    2521 (FUS)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:hsa03041]
    2521 (FUS)
Spliceosome [BR:hsa03041]
Complex A
  Other components
   Complex A specific factors
    2521 (FUS)

SSDB

Motif

Pfam:

RRM_1 Zn_ribbon_RanBP

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Structure

LinkDB

Position

16:31180110..31194871

AA seq 526 aa
MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQ
SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSS
SYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQD
QSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYE
PRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIES
VADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFS
GNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQ
QRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYD
RGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY

NT seq 1581 nt +upstreamnt +downstreamnt
atggcctcaaacgattatacccaacaagcaacccaaagctatggggcctaccccacccag
cccgggcagggctattcccagcagagcagtcagccctacggacagcagagttacagtggt
tatagccagtccacggacacttcaggctatggccagagcagctattcttcttatggccag
agccagaacacaggctatggaactcagtcaactccccagggatatggctcgactggcggc
tatggcagtagccagagctcccaatcgtcttacgggcagcagtcctcctaccctggctat
ggccagcagccagctcccagcagcacctcgggaagttacggtagcagttctcagagcagc
agctatgggcagccccagagtgggagctacagccagcagcctagctatggtggacagcag
caaagctatggacagcagcaaagctataatccccctcagggctatggacagcagaaccag
tacaacagcagcagtggtggtggaggtggaggtggaggtggaggtaactatggccaagat
caatcctccatgagtagtggtggtggcagtggtggcggttatggcaatcaagaccagagt
ggtggaggtggcagcggtggctatggacagcaggaccgtggaggccgcggcaggggtggc
agtggtggcggcggcggcggcggcggtggtggttacaaccgcagcagtggtggctatgaa
cccagaggtcgtggaggtggccgtggaggcagaggtggcatgggcggaagtgaccgtggt
ggcttcaataaatttggtggccctcgggaccaaggatcacgtcatgactccgaacaggat
aattcagacaacaacaccatctttgtgcaaggcctgggtgagaatgttacaattgagtct
gtggctgattacttcaagcagattggtattattaagacaaacaagaaaacgggacagccc
atgattaatttgtacacagacagggaaactggcaagctgaagggagaggcaacggtctct
tttgatgacccaccttcagctaaagcagctattgactggtttgatggtaaagaattctcc
ggaaatcctatcaaggtctcatttgctactcgccgggcagactttaatcggggtggtggc
aatggtcgtggaggccgagggcgaggaggacccatgggccgtggaggctatggaggtggt
ggcagtggtggtggtggccgaggaggatttcccagtggaggtggtggcggtggaggacag
cagcgagctggtgactggaagtgtcctaatcccacctgtgagaatatgaacttctcttgg
aggaatgaatgcaaccagtgtaaggcccctaaaccagatggcccaggagggggaccaggt
ggctctcacatggggggtaactacggggatgatcgtcgtggtggcagaggaggctatgat
cgaggcggctaccggggccgcggcggggaccgtggaggcttccgagggggccggggtggt
ggggacagaggtggctttggccctggcaagatggattccaggggtgagcacagacaggat
cgcagggagaggccgtattaa

DBGET integrated database retrieval system