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KEGG   Bison bison bison (American bison): 104995378
Entry
104995378         CDS       T08726                                 
Symbol
AXL
Name
(RefSeq) tyrosine-protein kinase receptor UFO isoform X1
  KO
K05115  AXL receptor tyrosine kinase [EC:2.7.10.1]
Organism
bbis  Bison bison bison (American bison)
Pathway
bbis01521  EGFR tyrosine kinase inhibitor resistance
bbis04148  Efferocytosis
Brite
KEGG Orthology (KO) [BR:bbis00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    104995378 (AXL)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    104995378 (AXL)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bbis01001]
    104995378 (AXL)
Enzymes [BR:bbis01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     104995378 (AXL)
Protein kinases [BR:bbis01001]
 Receptor tyrosine kinases (RTK)
  AXL family
   104995378 (AXL)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Ig_3 fn3 Ig_2 I-set ig V-set C2-set_2 DUF2627 DUF4381 Pkinase_fungal C1-set Reovirus_L2_6th
Other DBs
NCBI-GeneID: 104995378
NCBI-ProteinID: XP_010847561
UniProt: A0A6P3I753
LinkDB
Position
Unknown
AA seq 887 aa
MGKVLLAWCWALCCWGRVAPKGPQTEVSPFVGSPGNITGARGLMGTLRCELQVQGEPPEV
TWLRDGQVLELADSTQTQVPLGEDGQDDWKVVSQLRISSLQLSDAGWYQCAVVLGEKTFV
SQPGYVGLEGLPYFLEEPEDRTVVANTPFNLSCRAQGPPEPVDLLWLQDAVSLASAMDHS
PQHTLRVPGLNKTASFSCEAHNAKGITTSRTATITVLPQRPHDLHLVSTQPTELEVAWTP
GLSGIYPLTHCILQAVLSDDRVGAWLGEPDPPEEPLTLQASVPPHQLRLGSLHPHTPYHL
RVACVSSQGPSPWTHWLPVETPEGVPLGPPENVSAMRNGSQALVRWQEPRAPLQGTLLGY
RLAYRGQDTPEVLMDVGLKREVTLELRGEGSVPNLTVYVAAYTAAGDGPWSLPVPLEPWR
PGQGQPIHQLVSEPPAPAFSWPWWYVLLGAVVAAACVLILALFLFHRRKKETRYGEVFEP
TVERGELVVRYRVRKSYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVALGKTLGEGEF
GAVMEGQLNQDDSVLKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQG
SEREGFPAPVVILPFMKHGDLHSFLLYSRLGDQPVFLPTQMLVKFMADIASGMEYLSTKR
FIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRVYT
SKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLRQGNRLKQPVDCLDGLYALMSRCWE
LNPRDRPSFAELREDLENTLKALPPAQEPDEILYVNMDEGGGHSEPLGAAGGADPPAQPD
PKDSCSCLTAAEVHPAGRYVLCPSTAPGPILPAERSSPAPPGQEDGA
NT seq 2664 nt   +upstreamnt  +downstreamnt
atgggcaaggtcctgttggcttggtgctgggcgttgtgctgctgggggcgcgtggctccc
aagggcccacagactgaagtgtccccctttgtggggagtccggggaacatcaccggtgcc
cgaggactcatgggcacccttcggtgtgagctccaggttcagggggagccccctgaggtg
acctggcttcgggatggacaggtcctagagctggcagacagcacccagacccaggtgccc
ctgggcgaagacgggcaggatgactggaaagtggtcagccaactcagaatctcgtctctg
cagctctcagatgcgggatggtaccagtgcgccgtggtcctgggagaaaagacctttgtg
tctcagcctggctacgtggggctggaaggcctgccttacttcctggaggagcctgaggac
aggactgtggttgccaacactcccttcaacctgagctgccgggcgcagggacccccagag
cccgtggacctcctctggctccaggatgctgtctccctggcttcagccatggaccacagc
ccccagcacacactccgtgttccaggcctgaacaagactgcttctttctcctgtgaagcc
cacaatgccaaggggatcaccacatcccgcacggccaccatcacagtgctcccccagcgg
ccccacgacctccacttggtttccacccagccgacggaactggaggtggcttggacccca
ggcctgagtggtatctaccccctcacccactgcattctgcaggctgtgctgtcagatgac
agggtgggcgcctggctgggagagccagaccccccagaggagcccctcaccttacaagcg
tccgttcctcctcatcaactacggctgggcagcctccatcctcacaccccttaccacctc
cgggtggcctgtgtcagtagccagggcccctcaccctggacccactggcttcctgtggag
acaccggaaggagtgcccctgggccctcctgagaatgttagcgccatgcggaatgggagt
caagcccttgtgcgttggcaggagccaagggcgccgctgcagggcaccctgttagggtac
cgactggcctatcgaggtcaggatacgcccgaggtgctgatggacgtagggctaaagcga
gaggtgaccctggagctgcgaggggaggggtctgtgcccaacctgacggtgtacgtggca
gcctacaccgccgctggggacggaccctggagcctccctgtgcccctggagccctggcgc
ccaggacaaggacagccaatccaccagctggtgagtgaacccccagcccccgccttctcg
tggccctggtggtatgtactgctgggagcagtggtggccgccgcctgtgtcctcatcctg
gccctgttcctcttccaccggcggaagaaggagacccgttatggagaggtgtttgaacca
accgtggagaggggtgagctggtggtcaggtaccgtgttcgcaagtcctacagtcggagg
accactgaagccaccttgaacagcctcggcatcagcgaagagctgaaggagaaactgcgg
gatgtgatggtggaccggcataaggtggctctggggaagaccctgggagagggagagttc
ggagctgtgatggaaggccagctcaaccaggacgactctgtcctcaaggtggctgtgaag
accatgaagattgccatctgcacaaggtcggagctggaggatttcctgagtgaagccgtc
tgcatgaaggaattcgaccaccccaacgtcatgaggctcattggcgtttgtttccagggt
tctgaacgagaaggcttcccggcgcccgtggtcatcttacccttcatgaaacacggagac
ctacacagtttccttctctattcccggctcggggaccagccagtgttcctgcccacccag
atgctggtgaagttcatggcagatattgccagtggcatggagtatctgagtaccaagaga
ttcatacaccgggacctggctgctaggaattgcatgctgaatgagaacatgtcggtgtgt
gtggctgactttgggctctccaagaagatctacaacggggactactaccgtcagggacgc
atcgccaagatgccggtcaagtggattgccatcgagagcctggcagaccgtgtctatacc
agcaagagcgatgtatggtcctttggggtgacgatgtgggagattgccacgcgagggcaa
accccatatccaggagtggagaacagtgagatttatgactacctgcgccagggaaaccgc
ctgaagcagcccgtggactgtctggacggactgtacgccctgatgtcccggtgctgggag
ctaaacccccgggaccggccgagttttgcagagctgcgggaagacctggagaatacgctg
aaggccctgccccctgctcaggagccagacgaaatcctctatgtcaacatggatgagggt
ggaggtcattctgaaccacttggagctgctggaggagcggaccccccagctcagcctgac
cctaaggattcctgcagctgcctcaccgccgctgaagtccatcctgccggccgctatgtc
ctctgcccttctacagcccctggccccatcctgcctgctgaaaggagctccccagcaccc
ccggggcaggaggacggcgcctga

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