KEGG REACTION: R03174

REACTION: R03174

Entry

R03174                      Reaction

Name

(S)-2-methylbutanoyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-(2-methylbutanoyl)transferase

Definition

(S)-2-Methylbutanoyl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine

Equation

C15980 + C15973 <=> C00010 + C15979

Comment

3-methyl-2-oxobutanoate dehydrogenase complexes:3-methyl-2-oxobutanoate dehydrogenase
a part of multi-step reaction (see R04225+R03174+R07618, possibly identical to R03171)
following after R04225

Reaction class

RC00004

C00010_C15980 C15973_C15979

RC02870

C15979_C15980

Enzyme

2.3.1.168

Pathway

rn00280

Valine, leucine and isoleucine degradation

rn00785

Lipoic acid metabolism

rn01100

Metabolic pathways

rn01110

Biosynthesis of secondary metabolites

Brite

Enzymatic reactions [BR:br08201]
2. Transferase reactions
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.168
     R03174  (S)-2-Methylbutanoyl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine

Orthology

K09699

2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168]

LinkDB

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