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KEGG   DRUG: Drospirenone and estradiol
Entry
D12497            Mixture   Drug                                   
Name
Drospirenone and estradiol;
Angeliq (TN)
Product
ANGELIQ (Bayer HealthCare Pharmaceuticals)
Component
Drospirenone [DR:D03917], (Estradiol [DR:D00105] | Estradiol hemihydrate [DR:D07918])
Class
Metabolizing enzyme substrate
 DG01633  CYP3A/CYP3A4 substrate
  DG02913  CYP3A4 substrate
Remark
Product: D12497<US>
Efficacy
Contraceptive
Comment
Drospirenone is primarily metabolized by CYP3A4.
Metabolism
Enzyme: CYP3A4 [HSA:1576]
Interaction
Brite
USP drug classification [BR:br08302]
 Contraceptives
  Oral Contraceptives Combinations
   Drospirenone/ Estradiol
    D12497  Drospirenone and estradiol
Drug groups [BR:br08330]
 Metabolizing enzyme substrate
  DG01633  CYP3A/CYP3A4 substrate
   DG02913  CYP3A4 substrate
    D12497  Drospirenone and estradiol
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D12497
Other DBs
PubChem: 497620910
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