| Entry |
|
|---|
| Name |
Pipemidic acid (INN);
Nuril (TN) |
|---|
| Formula |
C14H17N5O3
|
|---|
| Exact mass |
303.1331
|
|---|
| Mol weight |
303.32
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antibacterial
DG01550 Quinolone
Metabolizing enzyme inhibitor
DG01634 CYP1A2 inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Antibacterial, Nucleic acid biosynthesis inhibitor |
|---|
| Target |
|
|---|
| Interaction |
CYP inhibition: CYP1A2 [HSA: 1544]
|
|---|
| Structure map |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01M QUINOLONE ANTIBACTERIALS
J01MB Other quinolones
J01MB04 Pipemidic acid
D08379 Pipemidic acid (INN)
Drug groups [BR:br08330]
Antibacterial
DG01550 Quinolone
DG00631 Pipemidic acid
D08379 Pipemidic acid
Metabolizing enzyme inhibitor
DG01634 CYP1A2 inhibitor
DG00631 Pipemidic acid
D08379 Pipemidic acid
Antimicrobials [BR:br08307]
Antibacterials
Nucleic acid synthesis inhibitor
Other quinolone
D08379 Pipemidic acid (INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D08379
Drug groups [BR:br08330]
Antibacterial
DG01550 Quinolone
DG00631 Pipemidic acid
Metabolizing enzyme inhibitor
DG01634 CYP1A2 inhibitor
DG00631 Pipemidic acid
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Nucleic acid synthesis inhibitor
Other quinolone
DG00631 Pipemidic acid
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 22
1 N5x N 22.3300 -16.8700
2 C8y C 22.3300 -18.2700
3 N5x N 23.5200 -18.9700
4 C8x C 23.5200 -16.1700
5 C8y C 24.7800 -16.8700
6 C8y C 24.7800 -18.2700
7 N4y N 25.9700 -18.9700
8 C8x C 27.1600 -18.2700
9 C8y C 27.1600 -16.8700
10 C8y C 25.9700 -16.1700
11 O5x O 25.9700 -14.7700
12 C6a C 28.4200 -16.1700
13 O6a O 29.6100 -16.9400
14 O6a O 28.4200 -14.7700
15 N1y N 21.1400 -18.9700
16 C1b C 25.9700 -20.3700
17 C1a C 24.7100 -21.0700
18 C1x C 19.8800 -18.2700
19 C1x C 18.6900 -18.9700
20 N1x N 18.6900 -20.3700
21 C1x C 19.8800 -21.0700
22 C1x C 21.1400 -20.3700
BOND 24
1 9 12 1
2 12 13 1
3 1 2 1
4 12 14 2
5 2 3 2
6 2 15 1
7 3 6 1
8 7 16 1
9 5 4 1
10 16 17 1
11 5 6 2
12 6 7 1
13 7 8 1
14 8 9 2
15 9 10 1
16 15 18 1
17 18 19 1
18 19 20 1
19 20 21 1
20 21 22 1
21 22 15 1
22 10 5 1
23 4 1 2
24 10 11 2
|
|---|