| Entry |
|
|---|
| Name |
Levofloxacin (INN);
Cravit (TN);
Levaquin (TN) |
|---|
| Formula |
C18H20FN3O4
|
|---|
| Exact mass |
361.1438
|
|---|
| Mol weight |
361.37
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Product (DG00624): | D00588<JP/US> |
|
|---|
| Efficacy |
Antibacterial, Nucleic acid biosynthesis inhibitor |
|---|
| Target |
|
|---|
| Metabolism |
Transporter: SLCO1A2 [HSA: 6579]
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01M QUINOLONE ANTIBACTERIALS
J01MA Fluoroquinolones
J01MA12 Levofloxacin
D08120 Levofloxacin (INN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AE Fluoroquinolones
S01AE05 Levofloxacin
D08120 Levofloxacin (INN)
Drug groups [BR:br08330]
Antibacterial
DG01550 Quinolone
DG01549 Fluoroquinolone
DG00624 Levofloxacin
D08120 Levofloxacin
DG01966 Antitubercular
DG00624 Levofloxacin
D08120 Levofloxacin
Transporter substrate
DG02857 SLCO1A2 substrate
DG00624 Levofloxacin
D08120 Levofloxacin
Antimicrobials [BR:br08307]
Antibacterials
Nucleic acid synthesis inhibitor
Fluoroquinolone
D08120 Levofloxacin (INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug transporters
D08120
Drug groups [BR:br08330]
Antibacterial
DG01550 Quinolone
DG01549 Fluoroquinolone
DG00624 Levofloxacin
DG01966 Antitubercular
DG00624 Levofloxacin
Transporter substrate
DG02857 SLCO1A2 substrate
DG00624 Levofloxacin
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Nucleic acid synthesis inhibitor
Fluoroquinolone
DG00624 Levofloxacin
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 26
1 C8y C 25.4100 -18.2700
2 C8y C 24.2200 -18.9700
3 C8y C 25.4100 -16.8700
4 N4y N 26.6700 -18.9700
5 C8y C 23.0300 -18.2700
6 O2x O 24.2200 -20.3700
7 C8y C 26.6700 -16.1700
8 C8x C 24.2200 -16.1700
9 C8x C 27.8600 -18.2700
10 C1y C 26.6700 -20.3700
11 N1y N 21.7700 -18.9700
12 C8y C 23.0300 -16.8700
13 C1x C 25.4100 -21.0700
14 C8y C 27.8600 -16.8700
15 O5x O 26.6700 -14.7700
16 C1a C 27.8600 -21.0700
17 C1x C 21.7700 -20.3700
18 C1x C 20.5800 -18.2700
19 X F 21.7700 -16.1700
20 C6a C 29.0500 -16.1700
21 C1x C 20.5800 -21.0700
22 C1x C 19.3900 -18.9700
23 O6a O 30.2400 -16.8700
24 O6a O 29.0500 -14.7700
25 N1y N 19.3900 -20.3700
26 C1a C 18.1300 -21.0700
BOND 29
1 25 26 1
2 8 12 2
3 9 14 2
4 10 13 1
5 22 25 1
6 1 2 1
7 1 3 2
8 1 4 1
9 2 5 2
10 2 6 1
11 3 7 1
12 3 8 1
13 4 9 1
14 4 10 1
15 5 11 1
16 5 12 1
17 6 13 1
18 7 14 1
19 7 15 2
20 10 16 1 #Up
21 11 17 1
22 11 18 1
23 12 19 1
24 14 20 1
25 17 21 1
26 18 22 1
27 20 23 1
28 20 24 2
29 21 25 1
|
|---|