| Entry |
|
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| Name |
Chloropyramine hydrochloride;
Avapena (TN) |
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| Formula |
C16H20ClN3. HCl
|
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| Exact mass |
325.1113
|
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| Mol weight |
326.26
|
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| Structure |
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| Simcomp |
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| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
|
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| Remark |
|
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| Efficacy |
Antiallergic, H1 receptor antagonist |
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| Comment |
Phenbenzamine derivative
|
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| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04AA Antihistamines for topical use
D04AA09 Chloropyramine
D07679 Chloropyramine hydrochloride
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AC Substituted ethylene diamines
R06AC03 Chloropyramine
D07679 Chloropyramine hydrochloride
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00384 Chloropyramine
D07679 Chloropyramine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D07679 Chloropyramine hydrochloride
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00384 Chloropyramine
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 21
1 N5x N 23.5900 -18.9700
2 C8x C 23.5900 -20.4400
3 C8x C 24.8500 -21.1400
4 C8x C 26.0400 -20.4400
5 C8x C 26.0400 -18.9700
6 C8y C 24.8500 -18.2700
7 N1c N 24.8500 -16.8700
8 C1b C 23.5900 -16.1700
9 C1b C 26.0400 -16.1700
10 C1b C 27.2300 -16.8700
11 N1c N 28.4200 -16.1700
12 C1a C 29.6100 -16.8700
13 C1a C 28.4200 -14.7700
14 C8y C 22.4000 -16.8700
15 C8x C 21.2100 -16.1700
16 C8x C 20.0200 -16.8700
17 C8y C 20.0200 -18.2700
18 C8x C 21.2100 -18.9700
19 C8x C 22.4000 -18.2700
20 X Cl 18.7600 -19.0400
21 X Cl 32.0600 -19.4600
BOND 21
1 1 2 1
2 2 3 2
3 3 4 1
4 4 5 2
5 5 6 1
6 1 6 2
7 6 7 1
8 7 8 1
9 7 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 11 13 1
14 8 14 1
15 14 15 2
16 15 16 1
17 16 17 2
18 17 18 1
19 18 19 2
20 14 19 1
21 17 20 1
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