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KEGG   DRUG: Lidocaine hydrochloride and epinephrine bitartrate
Entry
D04813            Mixture   Drug                                   
Name
Lidocaine hydrochloride and epinephrine bitartrate;
Lidocaine hydrochloride and adrenaline bitartrate;
Ora (TN);
Lidosite (TN)
Product
LIDOCAINE HCI AND EPINEPHRINE (HF Acquisition Co LLC), LIDOCAINE HCI AND EPINEPHRINE (HF Acquisition Co LLC), LIDOCAINE HCI AND EPINEPHRINE WITH EPINEPHRINE (HF Acquisition Co LLC), XYLOCAINE (A-S Medication Solutions), XYLOCAINE (Fresenius Kabi USA), XYLOCAINE (Fresenius Kabi USA), XYLOCAINE (HF Acquisition Co LLC), XYLOCAINE (REMEDYREPACK), XYLOCAINE(R) -MPF (LIDOCAINE HCI AND EPINEPHRINE) (HF Acquisition Co LLC), XYLOCAINE-MPF WITH EPI (HF Acquisition Co LLC)
  Generic
LIDOCAINE (Benco Dental), LIDOCAINE (Benco Dental), LIDOCAINE (Darby Dental Supply), LIDOCAINE (Darby Dental Supply), LIDOCAINE (Henry Schein), LIDOCAINE (Henry Schein), LIDOCAINE (NDC), LIDOCAINE (Patterson Dental), LIDOCAINE (Patterson Dental), LIDOCAINE (Safco Dental Supply), LIDOCAINE (Septodont), LIDOCAINE (Septodont), LIDOCAINE (The Atlanta Dental Supply Company DBA Advanced Dental Products), LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE (IQ Dental), LIGNOSPAN FORTE (Septodont), LIGNOSPAN STANDARD (Septodont), XYLOCAINE (Dentsply Pharmaceutical)
Component
(Lidocaine hydrochloride [DR:D02086] | Lidocaine hydrochloride monohydrate [DR:D08127]), Epinephrine bitartrate [DR:D02149]
Class
Metabolizing enzyme substrate
 DG01892  CYP1A2 substrate
 DG01633  CYP3A/CYP3A4 substrate
  DG02913  CYP3A4 substrate
Remark
Therapeutic category: 2710
Product: D04813<JP/US>
Efficacy
Anesthetic (topical, dental)
Metabolism
Enzyme: CYP1A2 [HSA:1544], CYP3A4 [HSA:1576]
Interaction
Brite
USP drug classification [BR:br08302]
 Anesthetics
  Local Anesthetics
   Epinephrine/ Lidocaine
    D04813  Lidocaine hydrochloride and epinephrine bitartrate
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  27  Dental preparations
   271  Local anesthetics
    2710  Local anesthetics
     D04813  Lidocaine hydrochloride and epinephrine bitartrate
Drug groups [BR:br08330]
 Metabolizing enzyme substrate
  DG01892  CYP1A2 substrate
   D04813  Lidocaine hydrochloride and epinephrine bitartrate
  DG01633  CYP3A/CYP3A4 substrate
   DG02913  CYP3A4 substrate
    D04813  Lidocaine hydrochloride and epinephrine bitartrate
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D04813
Other DBs
PubChem: 17398182
LinkDB

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