| Entry |
|
|---|
| Name |
Amobarbital sodium (JAN/USP);
Amytal sodium (TN) |
|---|
| Formula |
C11H17N2O3. Na
|
|---|
| Exact mass |
248.1137
|
|---|
| Mol weight |
248.25
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01837 Barbiturate sedative-hypnotics
DG01567 GABA-A receptor agonist
Metabolizing enzyme inducer
DG02853 CYP3A/CYP3A4 inducer
|
|---|
| Remark |
|
|---|
| Efficacy |
Sedative-hypnotic |
|---|
| Comment |
Barbiturates
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07230 | GABA-A receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05C HYPNOTICS AND SEDATIVES
N05CA Barbiturates, plain
N05CA02 Amobarbital
D02252 Amobarbital sodium (JAN/USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01837 Barbiturate sedative-hypnotics
DG00916 Amobarbital
D02252 Amobarbital sodium
DG01567 GABA-A receptor agonist
DG00916 Amobarbital
D02252 Amobarbital sodium
Metabolizing enzyme inducer
DG02853 CYP3A/CYP3A4 inducer
DG00916 Amobarbital
D02252 Amobarbital sodium
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
GABA (ionotropic)
GABR
D02252 Amobarbital sodium (JAN/USP)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D02252
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01837 Barbiturate sedative-hypnotics
DG00916 Amobarbital
DG01567 GABA-A receptor agonist
DG00916 Amobarbital
Metabolizing enzyme inducer
DG02853 CYP3A/CYP3A4 inducer
DG00916 Amobarbital
|
|---|
| Other DBs |
|
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| LinkDB |
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| KCF data |
ATOM 17
1 C1z C 21.8287 -17.3774
2 C5x C 21.8287 -18.7879
3 C5x C 20.6106 -16.6723
4 C1b C 23.3150 -17.3833
5 C1b C 21.8171 -16.0252
6 N1x N 20.6106 -19.4933
7 O5x O 23.0411 -19.4933
8 N2x N 19.3867 -17.3774
9 O5x O 20.6106 -15.2677
10 C1b C 24.0203 -16.3809
11 C1a C 23.0295 -15.3141
12 C2y C 19.3867 -18.7879
13 C1c C 25.4540 -16.3866
14 O1a O 18.1625 -19.4933 #-
15 C1a C 26.1593 -17.6048
16 C1a C 26.1593 -15.1685
17 Z Na 16.0533 -19.5067 #+
BOND 16
1 1 2 1
2 1 3 1
3 1 4 1
4 1 5 1
5 2 6 1
6 2 7 2
7 3 8 1
8 3 9 2
9 4 10 1
10 5 11 1
11 6 12 1
12 10 13 1
13 12 14 1
14 13 15 1
15 13 16 1
16 8 12 2
|
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