| Entry |
|
|---|
| Name |
dl-Methylephedrine hydrochloride (JP18);
Methy-F (TN) |
|---|
| Formula |
C11H17NO. HCl
|
|---|
| Exact mass |
215.1077
|
|---|
| Mol weight |
215.72
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Cardiovascular agent
DG01456 Adrenergic receptor agonist
Unclassified
DG03282 Ephedrine-containing preparation
|
|---|
| Remark |
| Therapeutic category: | 2221 |
| Product (DG01229): | D02109<JP> |
| Product (mixture): | D04313<JP> D04342<JP> D08695<JP> |
|
|---|
| Efficacy |
Antitussive, Bronchodilator, Adrenergic receptor agonist |
|---|
| Comment |
Phenethylamine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
|---|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
22 Respiratory organ agents
222 Antitussives
2221 Ephedrines and Ephedra herbs
D02109 dl-Methylephedrine hydrochloride (JP18)
Classification of Japanese OTC drugs [BR:br08313]
Agents for nervous and sensory systems
01 Cold remedy (oral use)
D02109 dl-Methylephedrine hydrochloride (JP18)
Agents for respiratory organs
26 Antitussives and expectorants
D02109 dl-Methylephedrine hydrochloride (JP18)
Agents for urogenital organs and anus
30 Hemorrhoid drugs for external use
D02109 dl-Methylephedrine hydrochloride (JP18)
Agents for otolaryngologic use
69 Oral medicine for nasal inflammation
D02109 dl-Methylephedrine hydrochloride (JP18)
Risk category of Japanese OTC drugs [BR:br08312]
Designated second-class OTC drugs
Inorganic and organic chemicals
Methylephedrine
D02109 dl-Methylephedrine hydrochloride (JP18)
Second-class OTC drugs
Inorganic and organic chemicals
Methylephedrine
D02109 dl-Methylephedrine hydrochloride (JP18)
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01229 Methylephedrine
D02109 dl-Methylephedrine hydrochloride
Unclassified
DG03282 Ephedrine-containing preparation
D02109 dl-Methylephedrine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D02109 dl-Methylephedrine hydrochloride (JP18) <JP>
ADRA2
D02109 dl-Methylephedrine hydrochloride (JP18) <JP>
ADRB
D02109 dl-Methylephedrine hydrochloride (JP18) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D02109 dl-Methylephedrine hydrochloride
D02109 10% dl-Methylephedrine hydrochloride powder
Narcotics and psychotropics in Japan [br08308.html]
Stimulants by Control Act Article 2 Appended Table and Cabinet Order
D02109
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01229 Methylephedrine
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 14
1 C8x C 27.6287 -17.1735
2 C8x C 27.6287 -18.5731
3 C8x C 28.8416 -19.2728
4 C8x C 30.0545 -18.5731
5 C8y C 30.0545 -17.1735
6 C8x C 28.8416 -16.4738
7 C1c C 31.2674 -16.4738
8 C1c C 32.4804 -17.1735
9 N1c N 33.6933 -16.4738
10 C1a C 34.9062 -17.1735
11 C1a C 32.4804 -18.5731
12 O1a O 31.2674 -15.0743
13 C1a C 33.6933 -15.0743
14 X Cl 39.4336 -16.9402
BOND 13
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 8 11 1
12 7 12 1
13 9 13 1
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